ESR1 gene status correlates with estrogen receptor protein levels measured by ligand binding assay and immunohistochemistry

American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer

2006 • 4,319 citations

American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations for Immunohistochemical Testing of Estrogen and Progesterone Receptors in Breast Cancer

2010 • 3,835 citations

Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials

2011 • 2,756 citations

Estrogen Receptor Status by Immunohistochemistry Is Superior to the Ligand-Binding Assay for Predicting Response to Adjuvant Endocrine Therapy in Breast Cancer

1999 • 1,991 citations

Recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Update

2013 • 1,416 citations

Prognostic and Predictive Value of Centrally Reviewed Expression of Estrogen and Progesterone Receptors in a Randomized Trial Comparing Letrozole and Tamoxifen Adjuvant Therapy for Postmenopausal Early Breast Cancer: BIG 1-98

2007 • 435 citations

Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer

2007 • 369 citations

Estrogen Receptor (ER) mRNA and ER-Related Gene Expression in Breast Cancers That Are 1% to 10% ER-Positive by Immunohistochemistry

2012 • 248 citations

Peptide nucleic acids : protocols and applications

2004 • 220 citations

Steroid Receptors in Breast Cancer

1979 • 213 citations

Re-evaluating Adjuvant Breast Cancer Trials: Assessing Hormone Receptor Status by Immunohistochemical Versus Extraction Assays

2006 • 158 citations

Identification and validation of prognostic markers in breast cancer with the complementary use of array‐CGH and tissue microarrays

2005 • 149 citations

NCCN Task Force Report: Estrogen Receptor and Progesterone Receptor Testing in Breast Cancer by Immunohistochemistry

2009 • 140 citations

Standards for the assessment of estrogen receptors in human breast cancerReport of a workshop on September 29, 1972, at the Antoni van Leeuwenhoek-Huis, Amsterdam

1973 • 130 citations

Value of Epidermal Growth Factor Receptor, HER2, p53, and Steroid Receptors in Predicting the Efficacy of Tamoxifen in High-Risk Postmenopausal Breast Cancer Patients

2001 • 121 citations

Changes in breast cancer biomarkers in the IGF1R/PI3K pathway in recurrent breast cancer after tamoxifen treatment

2011 • 75 citations

Amplification of HER2 and TOP2A and deletion of TOP2A genes in breast cancer investigated by new FISH probes

2004 • 73 citations

Estrogen receptor α gene ESR1 amplification may predict endocrine therapy responsiveness in breast cancer patients

2009 • 70 citations

Gene amplification in ductal carcinoma in situ of the breast

2009 • 68 citations

Immunohistochemistry compared to cytosol assays for determination of estrogen receptor and prediction of the long-term effect of adjuvant tamoxifen

2010 • 58 citations

Short recurrence-free survival associated with high oestrogen receptor levels in the natural history of postmenopausal, primary breast cancer

1993 • 58 citations

Amplification of ESR1 may predict resistance to adjuvant tamoxifen in postmenopausal patients with hormone receptor positive breast cancer

2010 • 58 citations

ESR1 Is Co-Expressed with Closely Adjacent Uncharacterised Genes Spanning a Breast Cancer Susceptibility Locus at 6q25.1

2011 • 58 citations

Gene amplification ofESR1in breast cancers—fact or fiction? A fluorescencein situhybridization and multiplex ligation‐dependent probe amplification study

2011 • 50 citations

Simultaneous detection of TOP2A and HER2 gene amplification by multiplex ligation-dependent probe amplification in breast cancer

2009 • 43 citations

ESR1 amplification is rare in breast cancer and is associated with high grade and high proliferation: a multiplex ligation-dependent probe amplification study

2011 • 37 citations

Estrogen Receptor analyses in the Danish Breast Cancer Cooperative Group. History, methods, prognosis and clinical implications

2008 • 36 citations

An ER activity profile including ER, PR, Bcl-2 and IGF-IR may have potential as selection criterion for letrozole or tamoxifen treatment of patients with advanced breast cancer

2009 • 27 citations

Prognostic and predictive role of ESR1 status for postmenopausal patients with endocrine-responsive early breast cancer in the Danish cohort of the BIG 1-98 trial

2011 • 23 citations

Monoallelic amplification of estrogen receptor-alpha expression in breast cancer.

2000 • 21 citations

ESR1 Amplification is Rare in Breast Cancer and is Associated with High Grade and High Proliferation: A Multiplex Ligation-Dependent Probe Amplification Study

2010 • 19 citations

Lack of independent prognostic and predictive value of centromere 17 copy number changes in breast cancer patients with known HER2 and TOP2A status

2011 • 18 citations

Immunohistochemical assessment of oestrogen and progesterone receptors: correlations with the DCC method and clinical outcome in primary breast cancer patients

2000 • 8 citations