Activation of molecular oxygen by flavins and flavoproteins.

Flavins and Flavoproteins

1984 • 692 citations

Mechanisms of flavoprotein‐catalyzed reactions

1989 • 554 citations

The production of superoxide anion radicals in the reaction of reduced flavins and flavoproteins with molecular oxygen

1969 • 419 citations

Chemiluminescence of organic peroxides. Conversion of ground-state reactants to excited-state products by the chemically initiated electron-exchange luminescence mechanism

1979 • 384 citations

The Reactivity of Flavoproteins with Sulfite

1969 • 342 citations

Flavin-oxygen derivatives involved in hydroxylation by p-hydroxybenzoate hydroxylase.

1976 • 330 citations

Active-site probes of flavoproteins

1980 • 294 citations

Direct demonstration of superoxide anion production during the oxidation of reduced flavin and of its catalytic decomposition by erythrocuprein

1969 • 223 citations

Mechanistic studies on cyclohexanone oxygenase

1982 • 207 citations

The oxidative half-reaction of liver microsomal FAD-containing monooxygenase.

1981 • 202 citations

New flavins for old: artificial flavins as active site probes of flavoproteins

1986 • 197 citations

Spectral Properties of an Oxygenated Luciferase—Flavin Intermediate Isolated by Low-Temperature Chromatography

1973 • 194 citations

The oxidation of reduced flavin mononucleotide by molecular oxygen

1962 • 185 citations

Flavins and Flavoproteins 1993

1994 • 182 citations

Mechanism of Action of the Flavoenzyme Lactate Oxidase

1972 • 175 citations

Reaction of 3O2 with dihydroflavins. 1. N3,5-Dimethyl-1,5-dihydrolumiflavin and 1,5-dihydroisoalloxazines

1977 • 145 citations

Catalytic function of tyrosine residues in para-hydroxybenzoate hydroxylase as determined by the study of site-directed mutants.

1991 • 140 citations

The reductive half-reaction of liver microsomal FAD-containing monooxygenase.

1981 • 132 citations

Oxygen‐Flavin Chemistry

1984 • 115 citations

Flavins and Flavoproteins

2014 • 112 citations

Oxidation of amines by a 4a-hydroperoxyflavin

1980 • 108 citations

Monooxygen donation potential of 4a-hydroperoxyflavins as compared with those of a percarboxylic acid and other hydroperoxides. Monooxygen donation to olefin, tertiary amine, alkyl sulfide, and iodide ion

1983 • 105 citations

Cyclohexanone oxygenase: stereochemistry, enantioselectivity, and regioselectivity of an enzyme-catalyzed Baeyer-Villiger reaction

1983 • 104 citations

The Active Site of Spinach Glycolate Oxidase

1989 • 102 citations

Reactions of the 4a-hydroperoxide of liver microsomal flavin-containing monooxygenase with nucleophilic and electrophilic substrates.

1986 • 87 citations

On the Role of Pyridoxal 5'-Phosphate in Phosphorylase. III. Physicochemical Properties and Reconstitution of Apophosphorylase b^*

1966 • 85 citations

Identifications of the true carbon-13 nuclear magnetic resonance spectrum of the stable intermediate II in bacterial luciferase

1986 • 78 citations

The chemistry of a 1,5-diblocked flavin. 2. Proton and electron transfer steps in the reaction of dihydroflavins with oxygen

1983 • 76 citations

p-Hydroxybenzoate Hydroxylase from Pseudomonas fluorescens

1972 • 71 citations

Mechanism of bacterial bioluminescence: 4a,5-Dihydroflavin analogs as models for luciferase hydroperoxide intermediates and the effect of substituents at the 8-position of flavin on luciferase kinetics

1993 • 68 citations

On the reaction mechanism of phenol hydroxylase. New information obtained by correlation of fluorescence and absorbance stopped flow studies.

1993 • 67 citations

Substitution of Arg214 at the substrate‐binding site of p, ‐hydroxybenzoate hydroxylase from Pseudomonas fluorescens

1992 • 67 citations

The Mechanism of Action of the Flavoprotein Melilotate Hydroxylase

1973 • 64 citations

Effect of substrate and pH on the oxidative half-reaction of phenol hydroxylase.

1985 • 57 citations

Changes in the Catalytic Properties of p-Hydroxybenzoate Hydroxylase Caused by the Mutation Asn300Asp

1994 • 44 citations

Intermediates in flavoprotein catalyzed hydroxylations

1974 • 38 citations

pH dependence of the reoxidation of p-hydroxybenzoate hydroxylase 2,4-dihydroxybenzoate complex.

1984 • 35 citations

Interpretation of the spectra observed during oxidation of p-hydroxybenzoate hydroxylase reconstituted with modified flavins

1991 • 34 citations

Crystal Structures of Mutant Pseudomonas aeruginosa p-Hydroxybenzoate Hydroxylases: The Tyr201Phe, Tyr385Phe, and Asn300Asp Variants

1994 • 33 citations

Absorption spectra of radicals of substrates for p-hydroxybenzoate hydroxylase following electrophilic attack of the .OH radical in the 3 position.

1987 • 32 citations

Oxidation Kinetics of 1, 5-Dihydroflavin by Oxygen in Non-aqueous Solvent

1977 • 23 citations

Absorption spectra of radical forms of 2,4-dihydroxybenzoic acid, a substrate for p-hydroxybenzoate hydroxylase

1991 • 21 citations

Absorption spectra of the hydroxycyclohexadienyl radicals of substrates for phenol hydroxylase.

1990 • 15 citations