Long‐term depletion of cd8⁺ t cells in vivo in the rat: no observed role for cd8⁺ (cytotoxic/suppressor) cells in the immunoregulation of experimental allergic encephalomyelitis

Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo

1984 • 884 citations

Production of prostaglandin E and an interleukin-1 like factor by cultured astrocytes and C6 glioma cells.

1982 • 754 citations

Two subsets of rat T lymphocytes defined with monoclonal antibodies

1980 • 678 citations

T-cell clones specific for myelin basic protein induce chronic relapsing paralysis and demyelination

1985 • 522 citations

Vaccination against autoimmune encephalomyelitis with T-lymphocite line cells reactive against myelin basic protein

1981 • 520 citations

Loss of Suppressor T Cells in Active Multiple Sclerosis

1980 • 446 citations

The localization of populations of lymphocytes defined by monoclonal antibodies in rat lymphoid tissues.

1981 • 389 citations

Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-beta gene family.

1987 • 387 citations

Heterogeneity of Natural Killer Cells

1984 • 368 citations

Regulation of Cellular and Humoral Immune Responses by T-cell Subclasses

1977 • 368 citations

Authentic T helper CD4 (W3/25) antigen on rat peritoneal macrophages.

1985 • 353 citations

Functions of Rat T‐Lymphocyte Subsets Isolated by Means of Monoclonal Antibodies

1983 • 330 citations

Adoptive transfer of myelin basic protein-sensitized T cells produces chronic relapsing demyelinating disease in mice

1984 • 311 citations

Production of Immunoglobulin Isotypes by Ly-1 ⁺ B Cells in Viable Motheaten and Normal Mice

1986 • 290 citations

T-lymphocyte heterogeneity in the rat: separation of functional subpopulations using a monoclonal antibody.

1978 • 288 citations

Experimental autoimmune encephalomyelitis (EAE) mediated by T cell lines: process of selection of lines and characterization of the cells.

1982 • 261 citations

Experimental allergic encephalomyelitis in the absence of a classical delayed-type hypersensitivity reaction. Severe paralytic disease correlates with the presence of interleukin 2 receptor-positive cells infiltrating the central nervous system.

1987 • 182 citations

Peptide and nucleotide sequences of rat CD4 (W3/25) antigen: evidence for derivation from a structure with four immunoglobulin-related domains.

1987 • 157 citations

Prevention of diabetes in BioBreeding/Worcester rats with monoclonal antibodies that recognize T lymphocytes or natural killer cells.

1986 • 156 citations

SUPPRESSION OF ALLERGIC ENCEPHALOMYELITIS IN RATS BY MEANS OF ANTIBRAIN SERUM

1963 • 145 citations

An Analysis of Effector T Cell Generation and Function in Mice Exposed to Influenza A or Sendai Viruses

1981 • 137 citations

Experimental Allergic Encephalomyelitis in the Lewis Rat: Studies on the Mechanism of Recovery from Disease and Acquired Resistance to Reinduction

1979 • 134 citations

Purification of human C3b inactivator by monoclonal-antibody affinity chromatography

1982 • 122 citations

Selective loss of a subset of T helper cells in active multiple sclerosis.

1985 • 120 citations

Organ-Resident, Nonlymphoid Cells Suppress Proliferation of Autoimmune T-Helper Lymphocytes

1987 • 118 citations

Induction of IgE-secreting cells and IgE isotype-specific suppressor T cells in the respiratory lymph nodes of rats in response to antigen inhalation

1985 • 109 citations

Regulation of experimental allergic encephalomyelitis. II. Appearance of suppressor cells during the remission phase of the disease.

1980 • 101 citations

In Vivo Treatment of Rats with Monoclonal Anti‐T‐Cell Antibodies

1985 • 97 citations

The distribution of interleukin-2 receptor bearing lymphocytes in multiple sclerosis: evidence for a key role of activated lymphocytes.

1985 • 97 citations

Autoregulation of autoantibody synthesis in mercuric chloride nephritis in the Brown Norway rat I. A role for T suppressor cells

1984 • 80 citations

Suppressor T cells prevent experimental autoimmune encephalomyelitis in mice.

1977 • 80 citations

CD5-positive B cells in rheumatoid arthritis and chronic lymphocytic leukemia

1987 • 79 citations

MRC OX-52: a rat T-cell antigen.

1986 • 73 citations

Regulation of paralytic experimental allergic encephalomyelitis in rats: susceptibility to active and passive disease reinduction.

1981 • 69 citations

Defective suppressor cell function mediated by T8+ cell lines from patients with progressive multiple sclerosis.

1986 • 59 citations

Striking similarities between antigen receptor J pieces and sequence in the second chain of the murine CD8 antigen

1986 • 57 citations

HgCl₂ induces nonspecific immunosuppression in Lewis rats

1987 • 54 citations

Studies of experimental allergic encephalomyelitis by using encephalitogenic T cell lines and clones in euthymic and athymic mice.

1986 • 53 citations

Characterization of suppressor cells involved in regulation of experimental allergic encephalomyelitis

1976 • 46 citations

The mechanism of inhibition of experimental allergic encephalomyelitis in the rat by monoclonal antibody against CD4

1986 • 46 citations

Expression of apolipoprotein E by mouse brain astrocytes and its modulation by interferon-γ

1987 • 43 citations

Immunoregulation of passively induced allergic encephalomyelitis.

1986 • 36 citations

Suppressor T-lymphocytes in the spinal cord of Lewis rats recovered from acute experimental allergic encephalomyelitis

1984 • 35 citations

Regulation of self tolerance in experimental allergic encephalomyelitis. I. Differences between lymph node and spleen suppressor cells.

1978 • 30 citations

Regulation of Self Tolerance in Experimental Allergic Encephalomyelitis

1978 • 26 citations

Immunocytochemical identification and quantitation of mononuclear cells in the meninges during the development of chronic relapsing experimental allergic encephalomyelitis (CREAE) in the guinea pig

1986 • 25 citations

Immunosuppression of experimental allergic encephalomyelitis. III. In vitro evidence for induction of suppressor T lymphocytes in draining lymph node cells of animals immunized with myelin basic protein complexed to lipopolysaccharides.

1982 • 19 citations

Redistribution of LYT-bearing T cells in acute murine experimental allergic encephalomyelitis: selective migration of Lyt-1 cells to the central nervous system is associated with a transient depletion of Lyt-1 cells in peripheral blood

1985 • 16 citations

Leukocyte surface antigens in patients with multiple sclerosis

1984 • 16 citations

Immunosuppression with Monoclonal Antibodies — Rules for Effective Serotherapy

1985 • 13 citations

Redistribution of Lyt-bearing T cells in acute murine experimental allergic encephalomyelitis: selective migration of Lyt-1 cells to the central nervous system is associated with a transient depletion of Lyt-1 cells in peripheral blood.

1984 • 10 citations

SOME RECENT ADVANCES IN THE CLINICAL ASPECTS OF MULTIPLE SCLEROSIS

1980 • 4 citations