In situ dephosphorylation of tau by protein phosphatase 2A and 2B in fetal rat primary cultured neurons

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1991 • 4,043 citations

Tau proteins of alzheimer paired helical filaments: Abnormal phosphorylation of all six brain isoforms

1992 • 1,058 citations

Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain.

1989 • 989 citations

Modulation of the dynamic instability of tubulin assembly by the microtubule-associated protein tau.

1992 • 936 citations

Purification of tau, a microtubule-associated protein that induces assembly of microtubules from purified tubulin

1977 • 878 citations

Tau protein and the neurofibrillary pathology of Alzheimer's disease

1993 • 710 citations

Protein phosphatases come of age

1989 • 616 citations

Developmentally regulated expression of specific tau sequences

1989 • 589 citations

Mitogen activated protein (MAP) kinase transforms tau protein into an Alzheimer-like state.

1992 • 563 citations

Biopsy-derived adult human brain tau is phosphorylated at many of the same sites as Alzheimer's disease paired helical filament tau

1994 • 561 citations

Proline-directed and Non-proline-directed Phosphorylation of PHF-tau

1995 • 549 citations

Protein Serine/Threonine Phosphatases—New Avenues for Cell Regulation

1994 • 424 citations

Phosphorylation determines two distinct species of tau in the central nervous system

1987 • 405 citations

Tau proteins: the molecular structure and mode of binding on microtubules.

1988 • 363 citations

A novel pool of protein phosphatase 2A is associated with microtubules and is regulated during the cell cycle.

1995 • 305 citations

Brain proline-directed protein kinase phosphorylates tau on sites that are abnormally phosphorylated in tau associated with Alzheimer's paired helical filaments.

1993 • 289 citations

p42 map kinase phosphorylation sites in microtubule‐associated protein tau are dephosphorylated by protein phosphatase 2A₁ Implications for Alzheimer's disease

1992 • 273 citations

Dephosphorylation of Alzheimer Paired Helical Filaments by Protein Phosphatase-2A and −2B

1995 • 264 citations

Tau protein kinase I converts normal tau protein into A68-like component of paired helical filaments.

1992 • 246 citations

A cdc2‐related kinase PSSALRE/cdk5 is homologous with the 30 kDa subunit of tau protein kinase II, a proline‐directed protein kinase associated with microtubule

1993 • 235 citations

Phosphorylation sites on tau by tau protein kinase I, a bovine derived kinase generating an epitope of paired helical filaments

1992 • 146 citations

Alzheimer's Disease Abnormally Phosphorylated τ Is Dephosphorylated by Protein Phosphatase‐2B (Calcineurin)

1994 • 142 citations

The phosphorylation state of tau in the developing rat brain is regulated by phosphoprotein phosphatases.

1994 • 138 citations

Tau as a marker for Alzheimer's disease

1993 • 127 citations

The disordered neuronal cytoskeleton in Alzheimer's disease

1992 • 124 citations

A serine/threonine proline kinase activity is included in the tau protein kinase fraction forming a paired helical filament epitope

1991 • 109 citations

Microtubule stabilization by assembly‐promoting microtubule‐associated proteins: A repeat performance

1992 • 101 citations

Modulation of the phosphorylation state of tau in situ: the roles of calcium and cyclic AMP

1995 • 78 citations

Tau protein: An update on structure and function

1990 • 78 citations

Dephosphorylation of r Factor by Protein Phosphatase 2A in Synaptosomal Cytosol Fractions, and Inhibition by Aluminum

1990 • 72 citations

Evidence for cdk5 as a Major Activity Phosphorylating Tau Protein in Porcine Brain Extract1

1995 • 68 citations

Dephosphorylation of abnormal sites of tau factor by protein phosphatases and its implication for Alzheimer's disease

1995 • 27 citations

Improved protective groups for phosphate of o-phosphoserine useful for the solid-phase peptide synthesis

1991 • 25 citations