A Proficient Enzyme

The Kinetic Basis of Molecular Biology

1954 • 535 citations

Determination of kinetic constants for peptidyl prolyl cis-trans isomerases by an improved spectrophotometric assay

1991 • 506 citations

Purification and Properties of the Phosphotriesterase from Pseudomonas diminuta

1989 • 492 citations

The Catalytic Mechanism of Carbonic Anhydrase. Hydrogen-Isotope Effects on the Kinetic Parameters of the Human C Isoenzyme

1975 • 418 citations

TRANSITION STATE ANALOG INHIBITORS AND ENZYME CATALYSIS

1976 • 415 citations

Nmr studies of the rates of proline cis–trans isomerization in oligopeptides

1981 • 368 citations

Application of the Theory of Diffusion-controlled Reactions to Enzyme Kinetics

1958 • 348 citations

Transition-state stabilization and enzymic catalysis. Kinetic and molecular orbital studies of the rearrangement of chorismate to prephenate

1973 • 198 citations

Kinetic and magnetic resonance studies of effects of genetic substitution of a calcium-liganding amino acid in staphylococcal nuclease

1986 • 122 citations

The Kinetics and Rapid Thermochemistry of Carbonic Acid

1941 • 120 citations

Staphylococcal nuclease reviewed: A prototypic study in contemporary enzymology. I isolation; physical and enzymatic properties

1978 • 119 citations

Specificity and kinetics of triose phosphate isomerase from chicken muscle

1972 • 109 citations

Solvolysis of adenine nucleosides. I. Effects of sugars and adenine substituents on acid solvolyses

1972 • 109 citations

Mechanism of decarboxylation of 1,3-dimethylorotic acid. A model for orotidine 5'-phosphate decarboxylase

1976 • 104 citations

On the origin of the lactate dehydrogenase induced rate effect

1984 • 103 citations

Inhibition of orotidine-5'-phosphate decarboxylase by 1-(5'-phospho-.beta.-D-ribofuranosyl)barbituric acid, 6-azauridine 5'-phosphate, and uridine 5'-phosphate

1980 • 97 citations

The Kinetics of Some Carboxypeptidase A and Acetylcarboxypeptidase A Catalyzed Hydrolyses^*

1966 • 94 citations

Transition state stabilization by deaminases: Rates of nonenzymatic hydrolysis of adenosine and cytidine

1987 • 89 citations

Energetics of 3-oxo-.DELTA.5-steroid isomerase: source of the catalytic power of the enzyme

1991 • 86 citations

Uncatalyzed rates of enolization of dihydroxyacetone phosphate and of glyceraldehyde 3-phosphate in neutral aqueous solution. Quantitative assessment of the effectiveness of an enzyme catalyst

1975 • 73 citations

660. The reactions of organic phosphates. Part III. The hydrolysis of dimethyl phosphate

1960 • 63 citations

Selection of catalytic antibodies for a biosynthetic reaction from a combinatorial cDNA library by complementation of an auxotrophic Escherichia coli: antibodies for orotate decarboxylation.

1994 • 57 citations

.alpha.-Deuterium isotope effects and transition-state structure in an intramolecular model system for methyl-transfer enzymes

1979 • 56 citations

Investigation of the enzymic mechanism of yeast orotidine-5'-monophosphate decarboxylase using carbon-13 kinetic isotope effects

1991 • 55 citations

Orotidine-5'-monophosphate decarboxylase catalysis: kinetic isotope effects and the state of hybridization of a bound transition-state analog

1990 • 54 citations

The catalytic site of AMP nucleosidase. Substrate specificity and pH effects with AMP and formycin 5'-PO4.

1979 • 52 citations

A unique catalytic and inhibitor-binding role for Lys93 of yeast orotidylate decarboxylase

1992 • 52 citations

Determination of the microscopic rate constants for the base catalyzed conjugation of 5-androstene-3,17-dione

1989 • 43 citations

Spectrophotometric studies of nucleic acid derivatives and related compounds as a function of pH

1957 • 42 citations

Purification and characterization of yeast orotidine 5'-monophosphate decarboxylase overexpressed from plasmid PGU2

1991 • 30 citations

Adenosine deaminase from deoxycoformycin-sensitive and -resistant rat hepatoma cells. Purification and characterization.

1982 • 16 citations