Surfactant Protein-B Deficiency

Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology.

1994 • 866 citations

Pulmonary Surfactant Therapy

1993 • 659 citations

Targeted disruption of the surfactant protein B gene disrupts surfactant homeostasis, causing respiratory failure in newborn mice.

1995 • 639 citations

Deficiency of Pulmonary Surfactant Protein B in Congenital Alveolar Proteinosis

1993 • 630 citations

A mutation in the surfactant protein B gene responsible for fatal neonatal respiratory disease in multiple kindreds.

1994 • 561 citations

Surfactant and the Adult Respiratory Distress Syndrome

1993 • 554 citations

Function and regulation of expression of pulmonary surfactant-associated proteins

1991 • 418 citations

Hyaline membrane disease

1956 • 413 citations

Altered surfactant function and structure in SP-A gene targeted mice.

1996 • 408 citations

Mice deficient for the IL-3/GM-CSF/IL-5 βc receptor exhibit lung pathology and impaired immune response, while βIL3 receptor-deficient mice are normal

1995 • 313 citations

Hematopoietic and lung abnormalities in mice with a null mutation of the common beta subunit of the receptors for granulocyte-macrophage colony-stimulating factor and interleukins 3 and 5.

1995 • 311 citations

Pulmonary surfactant proteins

1994 • 239 citations

Hyaline Membrane Disease

1974 • 228 citations

Pulmonary surfactant and its apoproteins.

1990 • 199 citations

Human surfactant protein B: structure, function, regulation, and genetic disease

1995 • 192 citations

Lung transplantation for treatment of infants with surfactant protein B deficiency

1997 • 180 citations

Update on the Clinical Diagnosis, Management, and Pathogenesis of Pulmonary Alveolar Proteinosis (Phospholipidosis)

1984 • 157 citations

Ontogeny of Surfactant Proteins A and B in Human Amniotic Fluid as Indices of Fetal Lung Maturity

1991 • 155 citations

Partial Deficiency of Surfactant Protein B in an Infant With Chronic Lung Disease

1995 • 152 citations

Structure and Organization of the Gene Encoding Human Pulmonary Surfactant Proteolipid SP-B

1989 • 139 citations

Molecular and phenotypic variability in the congenital alveolar proteinosis syndrome associated with inherited surfactant protein B deficiency

1994 • 134 citations

Surfactant protein B deficiency: Antenatal diagnosis and prospective treatment with surfactant replacement

1994 • 131 citations

Ultrastructure of lung in surfactant protein B deficiency.

1994 • 117 citations

Localization, synthesis, and processing of surfactant protein SP-C in rat lung analyzed by epitope-specific antipeptide antibodies.

1994 • 115 citations

Expression of pulmonary surfactant protein D in rat gastric mucosa.

1995 • 97 citations

Experimental Neonatal Respiratory Failure Induced by a Monoclonal Antibody to the Hydrophobic Surfactant-Associated Protein SP-B

1991 • 90 citations

The Use of Synthetic Peptides in the Formation of Biophysically and Biologically Active Pulmonary Surfactants

1991 • 81 citations

Primary structure differences of human surfactant-associated proteins isolated from normal and proteinosis lung

1992 • 74 citations

In VitroandIn VivoTransfer and Expression of Human Surfactant SP-A- and SP-B-Associated Protein cDNAs Mediated by Replication-Deficient, Recombinant Adenoviral Vectors

1995 • 68 citations

Pulmonary alveolar proteinosis: experience with eight pediatric cases and a review.

1996 • 68 citations

Adenovirus-Mediated Gene Transfer to the Respiratory Tract of Fetal SheepIn Utero

1995 • 67 citations

Posttranslational processing of surfactant protein C in rat type II cells

1995 • 64 citations

Pathophysiology and Treatment of Surfactant Protein-B Deficiency

1995 • 61 citations

Adenoviral-mediated gene transfer of human surfactant protein B to respiratory epithelial cells.

1994 • 54 citations

Activity of pulmonary surfactant after blocking the associated proteins SP-A and SP-B

1991 • 51 citations

Adenovirus-mediated gene transfer to human fetal lung ex vivo

1995 • 15 citations

SURFACTANT PROTEIN (SP) B DEFICIENCY IN NEONATES WITH SEVERE RESPIRATORY FAILURE. • 2044

1996 • 5 citations

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