Early loss of the retinoblastoma gene is associated with impaired growth inhibitory innervation during melanotroph carcinogenesis in Rb+/- mice.

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

Mutation and Cancer: Statistical Study of Retinoblastoma

1971 • 7,335 citations

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

1983 • 1,952 citations

Identification and localization of synaptophysin, an integral membrane glycoprotein of Mr 38,000 characteristic of presynaptic vesicles

1985 • 1,425 citations

The mouse; its reproduction and development

1968 • 1,290 citations

Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis

1992 • 1,285 citations

Protein p38: an integral membrane protein specific for small vesicles of neurons and neuroendocrine cells.

1986 • 671 citations

Cooperative tumorigenic effects of germline mutations in Rb and p53

1994 • 374 citations

Extensive contribution of Rb-deficient cells to adult chimeric mice with limited histopathological consequences.

1994 • 289 citations

Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation.

1994 • 286 citations

Heterozygous Rb-1 delta 20/+mice are predisposed to tumors of the pituitary gland with a nearly complete penetrance.

1994 • 260 citations

Developmental rescue of an embryonic-lethal mutation in the retinoblastoma gene in chimeric mice.

1994 • 253 citations

Induction of apoptosis in catecholaminergic PC12 cells by L-DOPA. Implications for the treatment of Parkinson's disease.

1995 • 241 citations

Dopamine induces apoptosis-like cell death in cultured chick sympathetic neurons — A possible novel pathogenetic mechanism in Parkinson's disease

1994 • 222 citations

The induction of multiple cell cycle events precedes target-related neuronal death

1995 • 214 citations

Anterior pituitary development: Short tales from dwarf mice

1992 • 208 citations

The Retinoblastoma Protein: More than a Tumor Suppressor

1994 • 205 citations

Histological Evaluation of the Dopaminergic Regulation of Proopiomelandcortin Gene Expression in the Intermediate Lobe of the Rat Pituitary, Involving in Situ Hybridization and [3H]Thymidine Uptake Measurement*

1987 • 95 citations

Expression of the retinoblastoma protein is regulated in normal human tissues.

1994 • 86 citations

Equine Cushing’s Disease: Differential Regulation of β-Endorphin Processing in Tumors of the Intermediate Pituitary*

1988 • 81 citations

Cell type and differentiation dependent heterogeneity in retinoblastoma protein expression in SCID mouse fetuses.

1992 • 76 citations

Clathrin Binding and Assembly Activities of Expressed Domains of the Synapse-specific Clathrin Assembly Protein AP-3

1995 • 68 citations

Effects of heterozygosity for the Rb-1t19neo allele in the mouse.

1995 • 64 citations

Early Postnatal Development of Pituitary Intermediate Lobe Control in the Rat by Dopamine Neurons

1984 • 58 citations

Neurotrophins and their receptors in the rat pituitary gland: regulation of BDNF and trk B mRNA levels by adrenal hormones

1994 • 58 citations

Induction of apoptosis in murine ACTH‐secreting pituitary adenoma cells by bromocriptine

1994 • 55 citations

Characterization of a novel synapse-specific protein. I. Developmental expression and cellular localization of the F1-20 protein and mRNA

1992 • 44 citations

Melanotropins as Growth Factors^a

1993 • 42 citations

Inhibition of growth of human small cell lung cancer by bromocriptine

1995 • 41 citations

Leu-enkephalin-like immunoreactivity in proliferative lesions of the human adrenal medulla and extra-adrenal paraganglia

1983 • 40 citations

The onset of dopaminergic innervation during ontogeny decreases melanotrope proliferation in the intermediate lobe of the rat pituitary

1992 • 40 citations

Ontogenesis of proopiomelanocortin gene expression and regulation in the rat pituitary intermediate lobe

1990 • 38 citations

Quantitative effects of the retinoblastoma gene on mouse development and tissue-specific tumorigenesis.

1993 • 26 citations

Nerve growth factor-like activity in the rat pituitary intermediate lobe

1988 • 24 citations

EFFECTS OF PIMOZIDE AND BROMOCRIPTINE ON THE PROLIFERATION OF RAT PITUITARY PARS INTERMEDIA CELLS

1977 • 23 citations

α‐Melanocyte stimulating hormone promotes neurite outgrowth in chromaffin cells

1988 • 19 citations

Rat model of the human “Triton” tumor: direct genetic evidence for the myogenic differentiation capacity of schwannoma cells using the mutant neu gene as a cell lineage marker

1991 • 17 citations

Two new monoclonal antibodies provide immunohistochemical evidence for the unique biochemical similarity of the mouse globus pallidus, entopeduncular nucleus and substantia nigra pars reticulata

1990 • 17 citations

Induction of apoptosis in rat somatotrophin-secreting pituitary adenoma cells by bromocriptine.

1993 • 15 citations

Evidence for a Possible Dopaminergic Control of Pituitary Alpha-MSH during Ontogenesis in Mice

1981 • 12 citations

Susceptibility to tumors induced in mice by ethylnitrosourea is independent of retinoblastoma gene dosage.

1994 • 11 citations

Development of malignant fibrous histiocytoma induced by 7,12-dimethylbenz[a]anthracene in the rat: characterization of early atypical cells

1993 • 11 citations

Proliferative activity of cells of the intermediate lobe of the rat pituitary during the postnatal period

1992 • 11 citations

Ontogeny of proopiomelanocortin (POMC) gene expression in the intermediate lobe of the rat pituitary gland

1990 • 8 citations

The Potential of Melanotropins in the Treatment of Nervous System Diseases

1993 • 7 citations

Morphofunctional Aspects of Melanotrophic Cells Developing In Situ and In Vitro^a

1993 • 6 citations