Substrate Behavior of Plasminogen Activator Inhibitor-1 Is Not Associated with a Lack of Insertion of the Reactive Site Loop

Protein Inhibitors of Proteinases

1980 • 2,220 citations

Increased Plasma Levels of a Rapid Inhibitor of Tissue Plasminogen Activator in Young Survivors of Myocardial Infarction

1985 • 1,364 citations

Human α1-proteinase inhibitor

1984 • 773 citations

Endothelial cells produce a latent inhibitor of plasminogen activators that can be activated by denaturants.

1985 • 555 citations

Purification of an inhibitor of plasminogen activator (antiactivator) synthesized by endothelial cells.

1984 • 455 citations

Crystal structure of ovalbumin as a model for the reactive centre of serpins

1990 • 394 citations

Endothelial plasminogen activator inhibitor (PAI): a new member of the Serpin gene family.

1986 • 343 citations

Structural transition of α₁‐antitrypsin by a peptide sequentially similar to β‐strand s4A

1990 • 197 citations

The Inhibition Mechanism of Serpins

1995 • 176 citations

Crystal structure of cleaved human α1-antichymotrypsin at 2.7 å resolution and its comparison with other serpins

1991 • 166 citations

Substrate properties of C1 inhibitor Ma (alanine 434—-glutamic acid). Genetic and structural evidence suggesting that the P12-region contains critical determinants of serine protease inhibitor/substrate status

1991 • 147 citations

Identification of a conformationally distinct form of plasminogen activator inhibitor-1, acting as a noninhibitory substrate for tissue-type plasminogen activator.

1992 • 142 citations

The Tumor Suppressor Maspin Does Not Undergo the Stressed to Relaxed Transition or Inhibit Trypsin-like Serine Proteases.

1995 • 135 citations

The mechanism of the reaction between human plasminogen-activator inhibitor 1 and tissue plasminogen activator

1990 • 112 citations

Peptide-mediated inactivation of recombinant and platelet plasminogen activator inhibitor-1 in vitro.

1995 • 100 citations

Interconversions between active, inert and substrate forms of denatured/refolded type-1 plasminogen activator inhibitor

1993 • 92 citations

A substrate‐like form of plasminogen‐activator‐inhibitor type 1

1992 • 90 citations

Purification and Characterization of Active and Stable Recombinant Plasminogen‐Activator Inhibitor Accumulated at High Levels in Escherichia coli

1994 • 68 citations

The structural basis for neutrophil inactivation of C1̅ inhibitor

1989 • 62 citations

Conversion of plasminogen activator inhibitor-1 from inhibitor to substrate by point mutations in the reactive-site loop.

1994 • 58 citations

Pathophysiology of fibrinolysis

1994 • 50 citations

Proteolytically cleaved mutant antithrombin‐Hamilton has high stability to denaturation characteristic of wild type inhibitor serpins

1994 • 16 citations

The latent tendencies of PAI-1

1992 • 12 citations