Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase.

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

Deletion of a DNA Polymerase β Gene Segment in T Cells Using Cell Type-Specific Gene Targeting

1994 • 1,396 citations

Site-specific DNA recombination in mammalian cells by the Cre recombinase of bacteriophage P1.

1988 • 1,180 citations

GERM-LINE TRANSFORMATION OF MICE

1986 • 1,165 citations

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

1993 • 984 citations

Two distinct enhancers with different cell specificities coexist in the regulatory region of polyoma

1984 • 891 citations

Targeted oncogene activation by site-specific recombination in transgenic mice.

1992 • 687 citations

Tissue- and site-specific DNA recombination in transgenic mice.

1992 • 651 citations

Targeted insertion of exogenous DNA into the eukaryotic genome by the Cre recombinase.

1990 • 253 citations

Transgenes as probes for active chromosomal domains in mouse development

1988 • 251 citations

A beta-galactosidase hybrid protein targeted to nuclei as a marker for developmental studies.

1987 • 232 citations

An Improved CAT Assay for Promoter Analysis in Either Transgenic Mice or Tissue Culture Cells

1992 • 162 citations