Barbiturate reduction of calcium-dependent action potentials: Correlation with anesthetic action

The membrane actions of anesthetics and tranquilizers.

1972 • 2,194 citations

The Pharmacological Basis for Therapeutics

1981 • 1,896 citations

Spontaneous subthreshold activity at motor nerve endings

1952 • 1,820 citations

Co‐operative action of calcium ions in transmitter release at the neuromuscular junction

1967 • 1,326 citations

A study of synaptic transmission in the absence of nerve impulses

1967 • 888 citations

Pharmacological studies on presynaptic inhibition

1963 • 765 citations

Hypnotics and sedatives

1981 • 712 citations

Tetrodotoxin‐resistant electric activity in presynaptic terminals

1969 • 613 citations

Mouse spinal cord in cell culture. I. Morphology and intrinsic neuronal electrophysiologic properties

1977 • 510 citations

Presynaptic inhibition in the vertebrate central nervous system

2006 • 474 citations

Effect of barbiturates on ‘quantal’ synaptic transmission in spinal motoneurones

1969 • 429 citations

Drug blockade of open end‐plate channels.

1976 • 352 citations

Amino acid pharmacology of mammalian central neurones grown in tissue culture.

1978 • 270 citations

The effects of anaesthetics on synaptic excitation and inhibition in the olfactory bulb

1972 • 231 citations

Barbiturate enhancement of GABA-mediated inhibition and activation of chloride ion conductance: correlation with anticonvulsant and anesthetic actions

1981 • 198 citations

On the mechanism of barbiturate anaesthesia

1972 • 190 citations

Pentobarbital selectively enhances GABA-mediated post-synaptic inhibition in tissue cultured mouse spinal neurons

1976 • 177 citations

Different Actions of Anticonvulsant and Anesthetic Barbiturates Revealed by Use of Cultured Mammalian Neurons

1978 • 175 citations

Barbiturate inhibition of calcium uptake by depolarized nerve terminals in vitro.

1975 • 163 citations

Enhancement of GABA-mediated postsynaptic inhibition in cultured mammalian spinal cord neurons: A common mode of anticonvulsant action

1979 • 159 citations

Effects of two benzodiazepines, phenobarbitone, and baclofen on synaptic transmission in the cat cuneate nucleus

1976 • 155 citations

Pentobarbital: action on frog motoneurons

1975 • 153 citations

Presynaptic action of barbiturates in the frog spinal cord.

1975 • 117 citations

ELECTRICAL INVESTIGATION OF THE MONOSYNAPTIC PATHWAY THROUGH THE SPINAL CORD

1947 • 116 citations

Effects of ethanol and pentobarbital on release of acetylcholine from cerebral cortex slices.

1967 • 114 citations

Barbiturates Block Sodium and Potassium Conductance Increases in Voltage-Clamped Lobster Axons

1968 • 110 citations

SITE OF ACTION OF THIAMYLAL SODIUM ON THE MONOSYNAPTIC SPINAL REFLEX PATHWAY IN CATS

1964 • 109 citations

Anticonvulsant and anesthetic barbiturates

1979 • 104 citations

A STUDY OF THE EFFECTS OF ANAESTHESIA AND ASPHYXIA ON THE MONO-SYNAPTIC PATHWAY THROUGH THE SPINAL CORD

1947 • 102 citations

EFFECTS OF CENTRAL DEPRESSANT DRUGS UPON ACETYLCHOLINE RELEASE

1964 • 92 citations

Pentobarbital depression of stimulus-secretion coupling in brain— Selective inhibition of depolarization-induced calcium-dependent release

1977 • 87 citations

The mechanism of the blockade of synaptic transmission in the mammalian spinal cord by diethyl ether and by thiopental.

1963 • 80 citations

Effects of procaine, pentobarbital and halothane on synaptic transmission in the central nervous system.

1969 • 74 citations

Barbiturates block calcium uptake by stimulated and potassium-depolarized rat sympathetic ganglia.

1976 • 68 citations

The effect of barbiturates on [3H]GABA transport in rat cerebral cortex slices

1974 • 67 citations

Acute and chronic effects of barbiturates on depolarization-induced calcium influx into rat synaptosomes

1980 • 67 citations

Acute and chronic effects of barbiturates on depolarization-induced calcium influx into synaptosomes from rat brain regions.

1980 • 66 citations

Physiological and morphological identification of hypothalamic magnocellular neuroendocrine cells in goldfish preoptic nucleus*

1974 • 61 citations

Effects of ether and thiopental on spinal presynaptic terminals.

1963 • 51 citations

The active form of pentobarbital in squid giant axons.

1971 • 49 citations

Action of pentobarbital on sympathetic ganglion cells

1978 • 46 citations

Effects of pentobarbital on the regulation of acetylcholine content and release in different regions of rat brain

1977 • 45 citations

Presynaptic Action of Central Depressant Drugs: Inhibition of Depolarization–Secretion Coupling

1972 • 44 citations

Inhibition by pentobarbital of the acetylcholine release from the postganglionic parasympathetic neuron of the heart.

1979 • 37 citations

K–STIMULATED ACETYLCHOLINE RELEASE: INHIBITION BY SEVERAL BARBITURATES AND CHLORAL HYDRATE BUT NOT BY ETHANOL, CHLORDIAZEPOXIDE OR 11‐OH‐Δ⁹‐TETRAHYDROCANNABINOL

1979 • 36 citations

Effects of pentobarbital and Ca2+ on the resting and k+-stimulated release of several endogenous neurotransmitters from rat midbrain slices

1980 • 36 citations

Pentobarbital and synaptic high-affinity receptive sites for gamma-aminobutyric acid

1976 • 35 citations

Effect of barbiturates on release of endogenous amino acids from rat cortex slices

1979 • 34 citations

Antiepileptic drug distribution in cerebral cortex, Ammon's horn, and amygdala in man

1980 • 33 citations

Effects of acute and chronic barbiturate administration on synaptosomal calcium accumulation.

1979 • 33 citations

Differential Selectivity of Several Barbiturates on Experimental Seizures and Neurotoxicity in the Mouse

1979 • 30 citations

THE MECHANISM OF THE BLOCKADE OF SYNAPTIC TRANSMISSION IN THE MAMMALIAN SPINAL CORD BY DIETHYL ETHER AND BY THIOPENTAL

1964 • 30 citations

The effects of anaesthetic and convulsant barbiturates on the efflux of [3H]d-aspartate from brain minislices

1980 • 28 citations

Calcium-dependent action potentials in mouse spinal cord neurons in cell culture

1981 • 23 citations

The mode of action of phenobarbital on the excitable membrane of the node of Ranvier

1979 • 19 citations

Effects of barbiturates on inhibitory and excitatory responses to applied neurotransmitters in Aplysia.

1980 • 18 citations

Proceedings: The actions of halothane and pentobarbitone on the sensitivity of neurones in the guinea-pig prepiriform cortex to iontophoretically applied L-glutamate.

1974 • 16 citations

Inhibition of ?-aminobutyric acid release from rat cerebral cortex slices by barbiturate anesthesia

1978 • 13 citations

Pentobarbital: Differential effects on the depolarization-induced release of excitatory and inhibitory amino acids from cerebral cortex slices

1980 • 12 citations