Cyclophilin A and FKBP12 Interact with YY1 and Alter Its Transcriptional Activity

Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells.

1982 • 8,069 citations

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1991 • 4,043 citations

The mechanism of action of cyclosporin A and FK506

1992 • 2,127 citations

CAT constructions with multiple unique restriction sites for the functional analysis of eukaryotic promoters and regulatory elements

1987 • 1,792 citations

Cyclophilin: A Specific Cytosolic Binding Protein for Cyclosporin A

1984 • 1,670 citations

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

1991 • 1,479 citations

The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit.

1993 • 1,459 citations

Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor

1978 • 1,284 citations

Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin

1989 • 1,087 citations

Nuclear association of a T-cell transcription factor blocked by FK-506 and cyclosporin A

1991 • 1,054 citations

Transcriptional repression by YY1, a human GLI-Krüippel-related protein, and relief of repression by adenovirus E1A protein

1991 • 1,023 citations

Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B

1993 • 802 citations

The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun

1993 • 769 citations

Specific incorporation of cyclophilin A into HIV-1 virions

1994 • 736 citations

Cyclosporin A Specifically Inhibits Function of Nuclear Proteins Involved in T Cell Activation

1989 • 679 citations

Cyclosporin A, FK-506, and Rapamycin: Pharmacologic Probes of Lymphocyte Signal Transduction

1992 • 675 citations

Transcription activation by the adenovirus E1a protein

1989 • 667 citations

Functional association of cyclophilin A with HIV-1 virions

1994 • 632 citations

A vector for expressing GAL4(1–147) fusions tn mammalian cells

1989 • 558 citations

Regulation of the Yeast HO Gene

1985 • 526 citations

YY1 is an initiator sequence-binding protein that directs and activates transcription in vitro

1991 • 465 citations

FK506 and cyclosporin, molecular probes for studying intracellular signal transduction

1993 • 389 citations

Cloning of an Intrinsic Human TFIID Subunit That Interacts with Multiple Transcriptional Activators

1995 • 385 citations

Isolation of a candidate repressor/activator, NF-E1 (YY-1, delta), that binds to the immunoglobulin kappa 3' enhancer and the immunoglobulin heavy-chain mu E1 site.

1991 • 357 citations

Calcineurin acts in synergy with PMA to inactivate I kappa B/MAD3, an inhibitor of NF-kappa B.

1994 • 334 citations

Specific Interaction of Type I Receptors of the TGF-β Family with the Immunophilin FKBP-12

1994 • 321 citations

Evidence for physical interaction between the zinc-finger transcription factors YY1 and Sp1.

1993 • 310 citations

Delta, a transcription factor that binds to downstream elements in several polymerase II promoters, is a functionally versatile zinc finger protein.

1991 • 303 citations

NF-ATp, a T lymphocyte DNA-binding protein that is a target for calcineurin and immunosuppressive drugs.

1993 • 293 citations

Interaction between transcription factors Spl and YY1

1993 • 282 citations

Cyclosporin A, the cyclophilin class of peptidylprolyl isomerases, and blockade of T cell signal transduction.

1992 • 276 citations

TATA-binding protein-independent initiation: YY1, TFIIB, and RNA polymerase II direct basal transcription on supercoiled template DNA

1994 • 275 citations

Inhibition of Transcriptional Regulator Yin-Yang-1 by Association with c-Myc

1993 • 273 citations

Cyclosporin A, FK506 and rapamycin: more than just immunosuppression

1993 • 259 citations

Cloning of a negative transcription factor that binds to the upstream conserved region of Moloney murine leukemia virus.

1992 • 251 citations

DNA bending and orientation-dependent function of YY1 in the c-fos promoter.

1993 • 233 citations

Yin-yang 1 activates the c-myc promoter.

1993 • 187 citations

Phylogenetic footprinting reveals a nuclear protein which binds to silencer sequences in the human gamma and epsilon globin genes.

1992 • 183 citations

Increased mRNA expression of a laminin-binding protein in human colon carcinoma: complete sequence of a full-length cDNA encoding the protein.

1988 • 179 citations

Functional antagonism between YY1 and the serum response factor.

1992 • 168 citations

Identification of a negative regulatory domain in the human papillomavirus type 18 promoter: interaction with the transcriptional repressor YY1.

1992 • 142 citations

The nuclear factor YY1 participates in repression of the beta-casein gene promoter in mammary epithelial cells and is counteracted by mammary gland factor during lactogenic hormone induction.

1994 • 141 citations

The transcription factor YY1 binds to negative regulatory elements in the human cytomegalovirus major immediate early enhancer/promoter and mediates repression in nonpermissive cells

1994 • 140 citations

Binding of the ubiquitous nuclear transcription factor YY1 to a cis regulatory sequence in the human LINE-1 transposable element

1993 • 137 citations

The 25-kDa FK506-binding protein is localized in the nucleus and associates with casein kinase II and nucleolin.

1993 • 124 citations

Human transcription factor YY1 represses human immunodeficiency virus type 1 transcription and virion production

1994 • 123 citations

Complementary DNA encoding the human T-cell FK506-binding protein, a peptidylprolyl cis-trans isomerase distinct from cyclophilin.

1990 • 120 citations

YY1 represses rat serum amyloid A1 gene transcription and is antagonized by NF-kappa B during acute-phase response.

1994 • 116 citations

Bifunctional transcriptional properties of YY1 in regulating muscle actin and c-myc gene expression during myogenesis.

1994 • 115 citations

Nucleotide sequence of a cDNA coding for mouse cyclophilin

1990 • 111 citations

Relief of YY1-induced transcriptional repression by protein-protein interaction with the nucleolar phosphoprotein B23.

1994 • 110 citations

Two FKBP-related proteins are associated with progesterone receptor complexes.

1993 • 106 citations

A chimeric mammalian transactivator based on the lac repressor that is regulated by temperature and isopropyl beta-D-thiogalactopyranoside.

1991 • 98 citations

Adenovirus E1A proteins interact with the cellular YY1 transcription factor

1995 • 96 citations

Identification of a transcriptional initiator element in the cytochrome c oxidase subunit Vb promoter which binds to transcription factors NF-E1 (YY-1, delta) and Sp1.

1993 • 92 citations

YY1 represses beta-casein gene expression by preventing the formation of a lactation-associated complex.

1994 • 84 citations

Protein-DNA interactions in the epsilon-globin gene silencer.

1993 • 76 citations

Negative regulation of the BZLF1 promoter of Epstein-Barr virus

1991 • 74 citations

LINE-1: a human transposable element

1993 • 69 citations

Characterization of a silencer regulatory element in the human interferon-gamma promoter.

1994 • 62 citations

The Intracisternal A-Particle Upstream Element Interacts with Transcription Factor YY1 To Activate Transcription: Pleiotropic Effects of YY1 on Distinct DNA Promoter Elements

1993 • 62 citations

FK‐506–A Novel Immunosuppressant

1993 • 50 citations

The transcriptional regulator YY1 binds to the 5'-terminal region of B19 parvovirus and regulates P6 promoter activity

1994 • 38 citations

Immunosuppressants: Tools to investigate the physiological role of cytokines

1993 • 35 citations

Discovery of FK‐506 and Update

1993 • 35 citations

YY1 is involved in the regulation of the bi-directional promoter of the Surf-1 and Surf-2 genes

1994 • 30 citations

Nuclear protein-binding sites in a transcriptional control region of the rabbit alpha-globin gene.

1993 • 27 citations

cDNA encoding murine FK506-binding protein (FKBP): nucleotide and deduced amino acid sequences

1991 • 27 citations

Cyclosporin binding proteins

1993 • 26 citations

In vitro effects of cyclosporin A (CSA) on human hemopoietic cell lines

1982 • 19 citations

Molecular mode of action of cyclosporin and FK506in human thymocytes

1992 • 13 citations

Structural and Functional Features of the Peptidyl Prolyl Cis‐Trans Isomerase, Cyclophilin

1991 • 10 citations