Synthetic CD4 Peptide Derivatives That Inhibit HIV Infection and Cytopathicity

The Pharmacological Basis of Therapeutics

1976 • 8,675 citations

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1984 • 3,530 citations

T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

1984 • 2,441 citations

The T4 gene encodes the AIDS virus receptor and is expressed in the immune system and the brain

1986 • 2,020 citations

The differentiation and function of human T lymphocytes

1980 • 1,548 citations

Separation of functional subsets of human T cells by a monoclonal antibody.

1979 • 1,062 citations

Binding of HTLV-III/LAV to T4 ⁺ T Cells by a Complex of the 110K Viral Protein and the T4 Molecule

1986 • 988 citations

Functional Regions of the Envelope Glycoprotein of Human Immunodeficiency Virus Type 1

1987 • 883 citations

Evolutionary conservation of surface molecules that distinguish T lymphocyte helper/inducer and cytotoxic/suppressor subpopulations in mouse and man

1981 • 871 citations

Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptor

1987 • 827 citations

Role of the HTLV-III/LAV envelope in syncytium formation and cytopathicity

1986 • 804 citations

The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family

1985 • 669 citations

Clonal analysis of human cytotoxic T lymphocytes: T4+ and T8+ effector T cells recognize products of different major histocompatibility complex regions.

1982 • 600 citations

Induction of CD4-dependent cell fusion by the HTLV-III/LAV envelope glycoprotein

1986 • 593 citations

soluble form of CD4 (T4) protein inhibits AIDS virus infection

1988 • 530 citations

AIDS Retrovirus Induced Cytopathology: Giant Cell Formation and Involvement of CD4 antigen

1986 • 516 citations

Blocking of HIV-1 Infectivity by a Soluble, Secreted Form of the CD4 Antigen

1987 • 485 citations

HIV infection is blocked in vitro by recombinant soluble CD4

1988 • 446 citations

A soluble CD4 protein selectively inhibits HIV replication and syncytium formation

1988 • 425 citations

Soluble CD4 molecules neutralize human immunodeficiency virus type 1

1988 • 403 citations

Epitopes of the CD4 Antigen and HIV Infection

1986 • 379 citations

Antibodies to membrane structures that distinguish suppressor/cytotoxic and helper T lymphocyte subpopulations block the mixed leukocyte reaction in man.

1981 • 304 citations

Simple, Rapid, Quantitative, Syncytium-Forming Microassay for the Detection of Human Immunodeficiency Virus Neutralizing Antibody

1987 • 269 citations

Acid stability of several benzylic protecting groups used in solid-phase peptide synthesis. Rearrangement of O-benzyltyrosine to 3-benzyltyrosine

1973 • 269 citations

Seroepidemiologic survey of captive old‐world primates for antibodies to human and simian retroviruses, and isolation of a lentivirus from sooty mangabeys (Cercocebus atys)

1986 • 233 citations

Cloning of HTLV-4 and its relation to simian and human immunodeficiency viruses

1987 • 167 citations

Role of envelope glycoprotein carbohydrate in human immunodeficiency virus (HIV) infectivity and virus-induced cell fusion.

1986 • 140 citations

Specificity of OKT4+ cytotoxic T lymphocyte clones.

1982 • 136 citations

Methods of Protein Microcharacterization

1986 • 126 citations

A soluble recombinant polypeptide comprising the amino-terminal half of the extracellular region of the CD4 molecule contains an active binding site for human immunodeficiency virus.

1988 • 120 citations

HIV infection of primate lymphocytes and conservation of the CD4 receptor

1987 • 107 citations

In vitro growth characteristics of simian T-lymphotropic virus type III.

1985 • 104 citations

Possible involvement of the T4 molecule in T cell recognition of class II HLA antigens: evidence from studies of proliferative responses to SB antigens.

1983 • 69 citations

Blocking of human T lymphocyte functions by anti-Leu-2 and anti-Leu-3 antibodies: differential inhibition of proliferation and suppression.

1983 • 55 citations

Peptide studies using a fast atom bombardment high field mass spectrometer and data system. 4. Disulfide-containing peptides

1985 • 46 citations

Partial primary structure of the T4 antigens of mouse and sheep: assignment of intrachain disulfide bonds.

1986 • 44 citations

The receptor concept in evolution

1977 • 35 citations

Core formation and Earth's late accretionary history (reply)

1986 • 2 citations