The noninvasive assessment of myocardial viability

The stunned myocardium: prolonged, postischemic ventricular dysfunction.

1982 • 2,825 citations

Reversibility of Cardiac Wall-Motion Abnormalities Predicted by Positron Tomography

1986 • 1,306 citations

The hibernating myocardium

1989 • 1,256 citations

Results of coronary artery surgery in patients with poor left ventricular function (CASS).

1983 • 824 citations

Enhanced Detection of Ischemic but Viable Myocardium by the Reinjection of Thallium after Stress-Redistribution Imaging

1990 • 801 citations

Reversible ischemic left ventricular dysfunction: Evidence for the “hibernating myocardium”

1986 • 733 citations

Identification of viable myocardium by echocardiography during dobutamine infusion in patients with myocardial infarction after thrombolytic therapy: Comparison with positron emission tomography

1990 • 728 citations

A Randomized Trial of Coronary Artery Bypass Surgery

1985 • 689 citations

A perspective on the three large multicenter randomized clinical trials of coronary bypass surgery for chronic stable angina.

1985 • 589 citations

Identification of viable myocardium in patients with chronic coronary artery disease and left ventricular dysfunction. Comparison of thallium scintigraphy with reinjection and PET imaging with 18F-fluorodeoxyglucose.

1991 • 583 citations

Eleven-Year Survival in the Veterans Administration Randomized Trial of Coronary Bypass Surgery for Stable Angina

1984 • 573 citations

Quantitative planar rest-redistribution 201Tl imaging in detection of myocardial viability and prediction of improvement in left ventricular function after coronary bypass surgery in patients with severely depressed left ventricular function.

1993 • 521 citations

Uptake and retention of hexakis (2-methoxyisobutyl isonitrile) technetium(I) in cultured chick myocardial cells. Mitochondrial and plasma membrane potential dependence.

1990 • 463 citations

Ten-year follow-up of survival and myocardial infarction in the randomized Coronary Artery Surgery Study.

1990 • 458 citations

Late reversibility of tomographic myocardial thallium-201 defects: An accurate marker of myocardial viability

1988 • 406 citations

Positron emission tomography using fluorine-18 deoxyglucose in evaluation of coronary artery bypass grafting

1989 • 390 citations

Myocardial kinetics of technetium-99m-hexakis-2-methoxy-2-methylpropyl-isonitrile.

1988 • 388 citations

Nitroglycerin to Unmask Reversible Asynergy Correlation with Post Coronary Bypass Ventriculography

1974 • 323 citations

Feasibility of tomographic 99mTc-hexakis-2-methoxy-2-methylpropyl-isonitrile imaging for the assessment of myocardial area at risk and the effect of treatment in acute myocardial infarction.

1989 • 323 citations

Prospective assessment of regional myocardial perfusion before and after coronary revascularization surgery by Quantitative Thallium-201 scintigraphy

1983 • 301 citations

Regional perfusion, glucose metabolism, and wall motion in patients with chronic electrocardiographic Q wave infarctions: evidence for persistence of viable tissue in some infarct regions by positron emission tomography.

1986 • 287 citations

The extraction of thallium-201 by the myocardium.

1977 • 278 citations

Positron emission tomography detects tissue metabolic activity in myocardial segments with persistent thallium perfusion defects

1987 • 260 citations

Quantification of area at risk during coronary occlusion and degree of myocardial salvage after reperfusion with technetium-99m methoxyisobutyl isonitrile.

1990 • 250 citations

Immediate improvement of dysfunctional myocardial segments after coronary revascularization: Detection by intraoperative transesophageal echocardiography

1984 • 226 citations

Redistribution of thallium at rest in patients with stable and unstable angina and the effect of coronary artery bypass surgery.

1979 • 218 citations

Serial quantitative planar technetium-99m isonitrile imaging in acute myocardial infarction: Efficacy for noninvasive assessment of thrombolytic therapy

1989 • 212 citations

Postextrasystolic Potentiation as a Predictor of Potential Myocardial Viability: Preoperative Analyses Compared With Studies After Coronary Bypass Surgery

1977 • 198 citations

The persistent defect on exercise thallium imaging and its fate after myocardial revascularization: Does it represent scar or ischemia?

1985 • 194 citations

Rest and redistribution thallium-201 myocardial scintigraphy to predict improvement in left ventricular function after coronary arterial bypass grafting

1983 • 193 citations

Late results of surgical and medical therapy for patients with coronary artery disease and depressed left ventricular function

1985 • 192 citations

Are the kinetics of technetium-99m methoxyisobutyl isonitrile affected by cell metabolism and viability?

1990 • 188 citations

Altered myocardial states

1989 • 187 citations

Augmentation of Left Ventricular Contraction Pattern in Coronary Artery Disease by an Inotropic Catecholamine

1974 • 184 citations

Value of thallium-201 reinjection after delayed SPECT imaging for predicting reversible ischemia after coronary artery bypass grafting

1990 • 183 citations

Transient defects of resting thallium scans in patients with coronary artery disease.

1979 • 178 citations

Improved regional ventricular function after successful surgical revascularization

1984 • 176 citations

Preoperative Prediction of Reversible Myocardial Asynergy by Postexercise Radionuclide Ventriculography

1982 • 168 citations

Use of thallium-201 redistribution scintigraphy in the preoperative differentiation of reversible and nonreversible myocardial asynergy.

1981 • 156 citations

Effect of ischemia and postischemic dysfunction on myocardial uptake of technetium-99m-labeled methoxyisobutyl isonitrile and thallium-201

1989 • 154 citations

Comparison of thallium redistribution with rest “reinjection” imaging for the detection of viable myocardium

1990 • 148 citations

Regional perfusion, glucose metabolism, and wall motion in patients with chronic electrocardiographic Q wave infarctions: evidence for persistence of viable tissue in some infarct regions by positron emission tomography.

1986 • 148 citations

Myocardial thallium-201 kinetics in normal and ischemic myocardium.

1981 • 147 citations

The clinical role of metabolic imaging of the heart by positron emission tomography.

1991 • 136 citations

Incomplete redistribution in delayed thallium-201 single photon emission computed tomographic (SPECT) images: An overestimation of myocardial scarring

1988 • 132 citations

The frequency of late reversibility in SPECT thallium-201 stress-redistribution studies

1990 • 119 citations

Relation of left ventricular perfusion and wall motion with metabolic activity in persistent defects on thallium-201 tomography in healed myocardial infarction

1988 • 117 citations

Single photon emission computed tomography with technetium-99m hexakis 2-methoxyisobutyl isonitrile in acute myocardial infarction before and after thrombolytic treatment: Assessment of salvaged myocardium and prediction of late functional recovery

1990 • 116 citations

Myocardial kinetics of Tc-MIBI in canine myocardium after dipyridamole.

1990 • 112 citations

Technetium-99m isonitrile myocardial uptake at rest. II. Relation to clinical markers of potential viability

1989 • 96 citations

Metabolic evidence of viable myocardium in regions with reduced wall thickness and absent wall thickening in patients with chronic ischemic left ventricular dysfunction

1992 • 95 citations

Physiological basis of myocardial perfusion imaging with the technetium 99m agents

1991 • 94 citations

Survival following coronary artery bypass grafting in patients with severe angina pectoris (CASS)

1985 • 91 citations

Thallium 201 kinetics in stunned myocardium characterized by severe postischemic systolic dysfunction.

1990 • 78 citations

Differential uptake and apparent 201Tl washout after thallium reinjection. Options regarding early redistribution imaging before reinjection or late redistribution imaging after reinjection.

1992 • 78 citations

Segmental wall motion abnormalities in the absence of clinically documented myocardial infarction: Clinical significance and evidence of hibernating myocardium

1991 • 76 citations

Divergent kinetics of 201Tl and 99mTc-SESTAMIBI in cultured chick ventricular myocytes during ATP depletion.

1992 • 75 citations

Selection of angina-free patients with severe left ventricular dysfunction for myocardial revascularization

1980 • 73 citations

The effect of coronary artery bypass grafting on left ventricular systolic function at rest: Evidence for preoperative subclinical myocardial ischemia

1988 • 72 citations

Effect of coronary occlusion and myocardial viability on myocardial activity of technetium-99m-sestamibi.

1991 • 65 citations

Reversible segmental left ventricular dysfunction after coronary angioplasty.

1990 • 62 citations

F-18 deoxyglucose and stress N-13 ammonia positron emission tomography in anterior wall healed myocardial infarction

1988 • 59 citations

Improved long-term survival following myocardial revascularization in patients with severe left ventricular dysfunction

1981 • 53 citations

Relation of immediate and delayed thallium-201 distribution to localization of iodine-125 antimyosin antibody in acute experimental myocardial infarction

1983 • 52 citations

Can the extent of coronary artery disease be predicted from thallium-201 myocardial images?

1979 • 51 citations

Resting thallium-201 myocardial perfusion patterns in patients with severe left ventricular dysfunction: Differences between patients with primary cardiomyopathy, chronic coronary artery disease, or acute myocardial infarction

1986 • 41 citations

Frequency of late reversibility in stress-redistribution thallium-201 SPECT using an early reinjection protocol

1991 • 30 citations

Myocardial hibernation and “embalmment”

1990 • 29 citations

Detection of myocardial viability in stunned or hibernating myocardium by delayed emptying on radionuclide ventriculography

1991 • 11 citations

Improved survival with coronary bypass surgery in patients with three-vessel coronary disease and abnormal left ventricular function

1987 • 10 citations

Recovery of severe ischemic ventricular dysfunction after coronary artery bypass grafting

1988 • 8 citations

The significance of the abnormal rest Thallium-201 myocardial image in coronary artery disease

1979 • 5 citations

Detection of myocardial viability with positron emission tomography in a patient with ischemic cardiomyopathy.

1991 • 1 citations