c-Abl Activation Regulates Induction of the SEK1/Stress-activated Protein Kinase Pathway in the Cellular Response to 1-β-D-Arabinofuranosylcytosine

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

1994 • 3,219 citations

The stress-activated protein kinase subfamily of c-Jun kinases

1994 • 2,616 citations

Phosphorylation of c-jun mediated by MAP kinases

1991 • 1,495 citations

Neonatal lethality and lymphopenia in mice with a homozygous disruption of the c-abl proto-oncogene

1991 • 1,317 citations

The jun proto-oncogene is positively autoregulated by its product, Jun/AP-1

1988 • 1,256 citations

Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun

1994 • 978 citations

Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

1995 • 929 citations

Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1

1994 • 706 citations

Activation of the c-Abl tyrosine kinase in the stress response to DMA-damaging agents

1995 • 486 citations

A C-terminal protein-binding domain in the retinoblastoma protein regulates nuclear c-Abl tyrosine kinase in the cell cycle

1993 • 402 citations

c-Abl kinase regulates the protein binding activity of c-Crk.

1994 • 362 citations

Correlation of cytotoxicity with incorporation of ara-C into DNA.

1980 • 362 citations

The Mechanism of Action of Inhibitors of DNA Synthesis

1977 • 330 citations

Abl protein-tyrosine kinase selects the Crk adapter as a substrate using SH3-binding sites.

1994 • 313 citations

Activation of tyrosinase kinase and microfilament-binding functions of c-abl by bcr sequences in bcr/abl fusion proteins.

1991 • 286 citations

The nuclear tyrosine kinase c-abl negatively regulates cell growth

1994 • 277 citations

Dose schedule and antitumor studies of arabinosyl cytosine (NSC 63878).

1969 • 216 citations

Tyrosine phosphorylation of mammalian RNA polymerase II carboxyl-terminal domain.

1993 • 206 citations

Lethality of human myeloblasts correlates with the incorporation of arabinofuranosylcytosine into DNA.

1981 • 203 citations

Cell Cycle—Regulated Binding of c-Abl Tyrosine Kinase to DNA

1992 • 202 citations

Abl tyrosine kinase in signal transduction and cell-cycle regulation

1993 • 177 citations

Mutagenic analysis of the roles of SH2 and SH3 domains in regulation of the Abl tyrosine kinase.

1994 • 175 citations

Differential Phosphorylation of c-Abl in Cell Cycle Determined by cdc 2 Kinase and Phosphatase Activity

1990 • 157 citations

Src homology 2 domain as a specificity determinant in the c-Abl-mediated tyrosine phosphorylation of the RNA polymerase II carboxyl-terminal repeated domain.

1995 • 114 citations

Effects of 1-beta-D-arabinofuranosylcytosine incorporation on elongation of specific DNA sequences by DNA polymerase beta.

1988 • 108 citations

Effects of 1-beta-D-arabinofuranosylcytosine incorporation on eukaryotic DNA template function.

1984 • 104 citations

Activation of Src-like p56/p53lyn tyrosine kinase by ionizing radiation.

1994 • 95 citations

Sequence-specific effects of ara-5-aza-CTP and ara-CTP on DNA synthesis by purified human DNA polymerases in vitro: visualization of chain elongation on a defined template.

1987 • 75 citations

Ionizing Radiation Stimulates a Grb2-mediated Association of the Stress-activated Protein Kinase with Phosphatidylinositol 3-Kinase

1995 • 74 citations

Activation of the AP-1 transcription factor by arabinofuranosylcytosine in myeloid leukemia cells

1992 • 48 citations

Transcriptional regulation of c-jun gene expression by arabinofuranosylcytosine in human myeloid leukemia cells.

1990 • 48 citations

Replication intermediates formed during initiation of DNA synthesis in methotrexate-resistant CHOC 400 cells are enriched for sequences derived from a specific, amplified restriction fragment

1986 • 45 citations

Cell cycle arrest by tyrosine kinase Abl involves altered early mitogenic response.

1995 • 32 citations

Activation of serine/threonine protein kinases and early growth response 1 gene expression by tumor necrosis factor in human myeloid leukemia cells.

1995 • 23 citations

Activation of the early growth response 1 gene and nuclear pp90rsk in human myeloid leukemia cells by 1-(.beta.-D-arabinofuranosyl)cytosine

1993 • 19 citations