Obese gene expression: reduction by fasting and stimulation by insulin and glucose in lean mice, and persistent elevation in acquired (diet-induced) and genetic (yellow agouti) obesity.

Positional cloning of the mouse obese gene and its human homologue

1994 • 12,975 citations

Weight-Reducing Effects of the Plasma Protein Encoded by the obese Gene

1995 • 4,457 citations

Effects of the obese Gene Product on Body Weight Regulation in ob / ob Mice

1995 • 4,057 citations

Recombinant Mouse OB Protein: Evidence for a Peripheral Signal Linking Adiposity and Central Neural Networks

1995 • 3,302 citations

Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor

1994 • 1,055 citations

Effects of parabiosis of obese with diabetes and normal mice

1973 • 728 citations

Consensus Conference Statement

2005 • 507 citations

Increased expression in adipocytes of ob RNA in mice with lesions of the hypothalamus and with mutations at the db locus.

1995 • 466 citations

Evidence against either a premature stop codon or the absence of obese gene mRNA in human obesity.

1995 • 367 citations

Obesity, diabetes, and neoplasia in yellow A ^vy /‐ mice: ectopic expression of the agouti gene

1994 • 306 citations

Methods in investigative and diagnostic endocrinology

1975 • 242 citations

Transcriptional control of metabolic regulation genes by carbohydrates

1994 • 191 citations

Use of Tritiated Water for Measurement of 24-Hour Milk Intake in Suckling Lean and Genetically Obese (ob/ob) Mice

1979 • 52 citations

Enhanced sensitivity of pancreatic islets from preobese 2-week-old ob/ob mice to neurohormonal stimulation of insulin secretion.

1995 • 41 citations

Detection of messenger RNA and low-abundance heteronuclear RNA with single-stranded DNA probes produced by amplified primer extension labeling.

1993 • 27 citations

Insulin and glucose suppress hepatic glycogenolysis by distinct enzymatic mechanisms

1993 • 24 citations