Harry M. Vars Research Award: A New Model to Determine in Vivo the Relationship Between Amino Acid Transmembrane Transport and Protein Kinetics in Muscle

Protein turnover in mammalian tissues and in the whole body

1978 • 1,237 citations

Role of amino acid transport and countertransport in nutrition and metabolism.

1990 • 1,101 citations

Branched-Chain Amino Acid Metabolism

1999 • 754 citations

Leucine. A possible regulator of protein turnover in muscle.

1975 • 746 citations

Intracellular free amino acid concentration in human muscle tissue.

1974 • 733 citations

Effect of physiologic hyperinsulinemia on skeletal muscle protein synthesis and breakdown in man.

1987 • 519 citations

The regulation of amino acid transport in animal cells

1978 • 467 citations

The regulation of neutral amino acid transport in mammalian cells

1983 • 459 citations

Effect of insulin and plasma amino acid concentrations on leucine metabolism in man. Role of substrate availability on estimates of whole body protein synthesis.

1987 • 349 citations

The Formation of Glutamine and Alanine in Skeletal Muscle

1974 • 291 citations

Oxidation of leucine by rat skeletal muscle

1972 • 256 citations

Measurement of the rate of protein synthesis and compartmentation of heart phenylalanine

1978 • 246 citations

Oxidation of amino acids by diaphragms from fed and fasted rats

1972 • 232 citations

Tracers in metabolic research: radioisotope and stable isotope/mass spectrometry methods.

1984 • 218 citations

CHARACTERISTICS OF A GLUTAMINE CARRIER IN SKELETAL MUSCLE HAVE IMPORTANT CONSEQUENCES FOR NITROGEN LOSS IN INJURY, INFECTION, AND CHRONIC DISEASE

1986 • 206 citations

Relationship between glutamine concentration and protein synthesis in rat skeletal muscle

1988 • 206 citations

Differential effects of hyperinsulinemia and hyperaminoacidemia on leucine-carbon metabolism in vivo. Evidence for distinct mechanisms in regulation of net amino acid deposition.

1987 • 197 citations

Interorgan amino acid nutrition

1982 • 193 citations

Measurements of half-life of rat cardiac myosin heavy chain with leucyl-tRNA used as precursor pool.

1977 • 167 citations

Plasma reciprocal pool specific activity predicts that of intracellular free leucine for protein synthesis

1989 • 122 citations

An isotopic method for measurement of muscle protein synthesis and degradation in vivo

1987 • 120 citations

Characteristics of L‐glutamine transport in perfused rat skeletal muscle.

1987 • 115 citations

Direct determination of leucine metabolism and protein breakdown in humans using L‐[1‐¹³C, ¹⁵N]‐leucine and the forearm model

1985 • 83 citations

Characteristics of acidic, basic and neutral amino acid transport in the perfused rat hindlimb.

1989 • 83 citations

Effects of acute systemic hyperinsulinemia on forearm muscle proteolysis in healthy man.

1991 • 81 citations

The determination of lactate turnover in vivo with 3H- and 14C-labelled lactate. The significance of sites of tracer administration and sampling

1981 • 80 citations

Equilibration of leucine between the plasma compartment and leucyl-tRNA in the heart, and turnover of cardiac myosin heavy chain

1981 • 78 citations

The movement of amino acids between blood and skeletal muscle in the rat

1973 • 70 citations

Sample site selection for tracer studies applying a unidirectional circulatory approach

1987 • 63 citations

Branched-chain Amino Acid Nitrogen Transfer to Alanine In Vivo in Dogs

1980 • 61 citations

Computer analysis reveals changes in renal Na+-glucose cotransporter in diabetic rats

1989 • 56 citations

Cardiovascular effects associated with antidiuretic activity of vasopressin after blockade of its vasoconstrictor action in dehydrated dogs.

1986 • 46 citations

Amino acid exchange between plasma and erythrocytes in vivo in humans

1989 • 42 citations

Isolation of labelled aminoacyl transfer RNA from muscle Studies of the entry of labelled amino acids into acyl transfer RNA linkage in situ and its control by insulin

1969 • 37 citations

Neutral amino acid transport into rat skeletal muscle: Competition, adaptive regulation, and effects of insulin

1991 • 24 citations

The influx of amino acids into the heart of the rat.

1978 • 23 citations

Acute ischemia-reperfusion injury in the canine hindlimb.

1989 • 14 citations