Allele loss and mutation screen at the Peutz-Jeghers (LKB1) locus (19p13.3) in sporadic ovarian tumours

A serine/threonine kinase gene defective in Peutz–Jeghers syndrome

1998 • 1,588 citations

The Sensitivity of Single-Strand Conformation Polymorphism Analysis for the Detection of Single Base Substitutions

1993 • 692 citations

Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis

1997 • 487 citations

Peutz-Jeghers syndrome.

1997 • 325 citations

Allelotype of human ovarian cancer.

1991 • 257 citations

Sensitivity of single-strand conformation polymorphism and heteroduplex method for mutation detection in the cystic fibrosis gene

1994 • 190 citations

Mutations and impaired function of LKB1 in familial and non-familial Peutz-Jeghers syndrome and a sporadic testicular cancer

1999 • 159 citations

Inherited disorders associated with colorectal cancer.

1989 • 104 citations

Somatic Mutations in the Peutz-Jegners (LKB1/STKII) Gene in Sporadic Malignant Melanomas

1999 • 100 citations

Allelic imbalance at theLKB1 (STK11) locus in tumours from patients with Peutz-Jeghers' syndrome provides evidence for a hamartoma-(adenoma)-carcinoma sequence

1999 • 98 citations

Frequent somatic mutations in serine/threonine kinase 11/Peutz-Jeghers syndrome gene in left-sided colon cancer.

1998 • 89 citations

Comparative sensitivity of alternative single-strand conformation polymorphism (SSCP) methods.

1994 • 87 citations

Polymerase chain reaction allelotyping of human ovarian cancer

1994 • 87 citations

Genetic Pathways of Colorectal Carcinogenesis Rarely Involve thePTEN and LKB1 Genes Outside the Inherited Hamartoma Syndromes

1998 • 79 citations

Genetic Changes in Ovarian Cancer

1995 • 60 citations

Frequent deletion of chromosome 19 and a rare rearrangement of 19p13.3 involving the insulin receptor gene in human ovarian cancer.

1995 • 24 citations