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The pathophysiology of severe falciparum malaria

Data up to Jan 2025

Published1986
Citations64
References131

Total Citations Per Year

Abstract

References (131)

A physiological approach to hepatic drug clearance

1975 • 1,855 citations

Human cerebral malaria. A quantitative ultrastructural analysis of parasitized erythrocyte sequestration.

1985 • 839 citations

The release and fate of vaso‐active hormones in the circulation

1969 • 639 citations

The Significance of Iron in Infection

1981 • 603 citations

Intravascular activation of complement and acute lung injury. Dependency on neutrophils and toxic oxygen metabolites.

1982 • 554 citations

Dexamethasone Proves Deleterious in Cerebral Malaria

1982 • 479 citations

FORMATION AND ABSORPTION OF CEREBROSPINAL FLUID IN MAN

1968 • 471 citations

Prevention by granulocyte depletion of increased vascular permeability of sheep lung following endotoxemia.

1981 • 426 citations

Severe Hypoglycemia and Hyperinsulinemia in Falciparum Malaria

1983 • 415 citations

Malaria infection of the placenta in The Gambia, West Africa; its incidence and relationship to stillbirth, birthweight and placental weight

1983 • 412 citations

Thrombospondin binds falciparum malaria parasitized erythrocytes and may mediate cytoadherence

1985 • 364 citations

Plasmodium Falciparum Malaria

1971 • 356 citations

The structural and functional properties of thrombospondin

1986 • 333 citations

Malaria in African Infants and Children in Southern Nigeria

1952 • 304 citations

Plasmodium falciparum Maturation Abolishes Physiologic Red Cell Deformability

1984 • 303 citations

The Anaemia of P. falciparum Malaria

1980 • 297 citations

The structural and functional properties of thrombospondin

1986 • 261 citations

Placental pathologic changes in malaria. A histologic and ultrastructural study.

1982 • 252 citations

"ACCELERATED STARVATION" AND THE SKIPPED BREAKFAST IN LATE NORMAL PREGNANCY

1982 • 247 citations

Liver blood flow. I. Intrinsic and nervous control of liver blood flow.

1981 • 241 citations

Steroids and Brain Edema

1972 • 235 citations

RELATION OF RENAL IMPAIRMENT AND HAEMORRHAGIC DIATHESIS TO ENDOTOXAEMIA IN FULMINANT HEPATIC FAILURE

1974 • 213 citations

The Medical Times and Gazette

2024 • 213 citations

Plasma Insulin in Normal Late Pregnancy

1963 • 208 citations

QUININE AND SEVERE FALCIPARUM MALARIA IN LATE PREGNANCY

1985 • 204 citations

Monoclonal antibody OKM5 inhibits the in vitro binding of Plasmodium falciparum-infected erythrocytes to monocytes, endothelial, and C32 melanoma cells.

1985 • 193 citations

Pathological Processes in Malaria and Blackwater Fever.

1948 • 185 citations

Liver blood flow

1981 • 182 citations

Knob-positive and knob-negative Plasmodium falciparum differ in expression of a strain-specific malarial antigen on the surface of infected erythrocytes.

1984 • 178 citations

DOES ENDOTOXIN CAUSE BOTH THE DISEASE AND PARASITE DEATH IN ACUTE MALARIA AND BABESIOSIS?

1978 • 165 citations

Immune-mediated thrombocytopenia of malaria.

1983 • 161 citations

The Pathology of Acute Falciparum Malaria

1946 • 152 citations

Lack of Clinical Usefulness of the Limulus Test in the Diagnosis of Endotoxemia

1975 • 152 citations

PATHOPHYSIOLOGICAL AND PROGNOSTIC SIGNIFICANCE OF CEREBROSPINAL-FLUID LACTATE IN CEREBRAL MALARIA

1985 • 146 citations

Depletion of Coagulation Factors in Drug-Resistant Plasmodium Falciparum Malaria

1967 • 139 citations

The human materno-foetal relationship in malaria. II. Histological, ultrastructural and immunopathological studies of the placenta

1980 • 134 citations

Acute Renal Failure Due to Nephrotoxins

1970 • 129 citations

Alteration in the rheologic properties of plasmodium knowlesi-infected red cells. A possible mechanism for capillary obstruction

1971 • 128 citations

Mechanisms of Thrombocytopenia in Malignant Tertian Malaria

1973 • 125 citations

DO PATIENTS WITH CEREBRAL MALARIA HAVE CEREBRAL OEDEMA? A Computed Tomography Study

1983 • 122 citations

Cerebral Malaria

1978 • 116 citations

The Pathogenesis of Mammalian Malaria

1972 • 111 citations

Renal disease in acute Plasmodium falciparum infection in man

1979 • 108 citations

Acute Pulmonary Insufficiency in Falciparum Malaria: Summary of 12 Cases with Evidence of Disseminated Intravascular Coagulation

1974 • 106 citations

IgM antibodies to red cells and autoimmune anemia in patients with malaria *

1973 • 106 citations

Retinal Hemorrhage, A Common Sign of Prognostic Significance in Cerebral Malaria *

1983 • 105 citations

Plasmodial pigmentation of placenta and outcome of pregnancy in West African mothers.

1983 • 104 citations

Plasmodium Falciparum Malaria

1982 • 104 citations

Acute Pulmonary Edema in falciparum Malaria

1968 • 97 citations

Function of the Blood-Cerebrospinal Fluid Barrier in Human Cerebral Malaria: Rejection of the Permeability Hypothesis

1986 • 97 citations

Hypoglycaemia and antimalarial drugs: quinidine and release of insulin.

1986 • 95 citations

Low birth-weight and malarial infection of the placenta.

1968 • 95 citations

Malaria-induced thrombocytopenia

1981 • 92 citations

In vitro and in vivo stimulation of rat neutrophils and alveolar macrophages by immune complexes. Production of O-2 and H2O2.

1983 • 88 citations

Ultrastructure of the Lung in Falciparum Malaria

1985 • 88 citations

The sequestration of Plasmodium falciparum infected erythrocytes in the placenta

1979 • 85 citations

Membrane-Associated Electron-Dense Material of the Asexual Stages of Plasmodium falciparum: Evidence for Movement from the Intracellular Parasite to the Erythrocyte Membrane

1986 • 84 citations

INTRAVASCULAR COAGULATION IN FALCIPARUM MALARIA

1972 • 82 citations

Cryoglobulins, circulating immune complexes, and complement activation in cerebral malaria

1981 • 81 citations

Malaria and Prematurity in the Western Region of Nigeria

1958 • 79 citations

The Nephrotic Syndrome Secondary to Acute Glomerulonephritis During Falciparum Malaria

1967 • 76 citations

COMPLEMENT CHANGES AND DISSEMINATED INTRAVASCULAR COAGULATION IN PLASMODIUM FALCIPARUM MALARIA

1975 • 75 citations

Complement activation in children with acute malaria.

1974 • 71 citations

FIBRIN-DEGRADATION PRODUCTS IN CEREBRAL MALARIA

1972 • 70 citations

The influence of malarial infection of the placenta on the incidence of prematurity.

1956 • 69 citations

Acute Renal Insufficiency Due to Falciparum Malaria

1972 • 68 citations

125I-LABELLED FIBRINOGEN IN CEREBRAL MALARIA

1966 • 67 citations

Recent studies on factors involved in malarial anemia.

1966 • 67 citations

The placenta in malaria with special reference to reticulo-endothelial immunity

1938 • 62 citations

Albumin Exchange Between Plasma and Cerebrospinal Fluid

1967 • 58 citations

Malabsorption in Plasmodium Falciparum Malaria *

1972 • 58 citations

Relationship of alterations in splenic clearance function and microcirculation to host defense in acute rodent malaria.

1981 • 58 citations

Direct antiglobulin reactions in Gambian children with P. falciparum malaria. III. Expression of IgG subclass determinants and genetic markers and association with anaemia.

1980 • 57 citations

Disseminated intravascular coagulation with fatal haemorrhage in cerebral malaria.

1970 • 55 citations

The direct antiglobulin test in P. falciparum malaria

1982 • 55 citations

OLIGURIA IN BLACKWATER FEVER

1944 • 54 citations

Renal Failure in Malaria: A Pathophysiologic Study

1977 • 53 citations

The Circulation in Malaria

1964 • 53 citations

Cerebral Malaria in the Gold Coast African Four Autopsy Reports

1954 • 52 citations

Pulmonary damage associated with falciparum malaria; a report of ten cases

1985 • 52 citations

Malaria Infection as it Occurs in Late Pregnancy; Its Relationship to Labour and Early Infancy

1925 • 51 citations

Electron microscopy of knobs in Plasmodium falciparum-infected erythrocytes.

1983 • 50 citations

Recent Studies on Factors Involved in Malarial Anemia

1966 • 47 citations

Electron Microscopy of Knobs in Plasmodium falciparum-Infected Erythrocytes

1983 • 43 citations

Pathophysiology of Malaria

1969 • 42 citations

Endotoxin in human and murine malaria

1980 • 42 citations

A new look at nonparasitized red cells of malaria-infected monkeys

1982 • 42 citations

Histopathologic Changes and Small-Bowel Absorption in Falciparum Malaria *

1969 • 41 citations

Acute Renal Failure in Plasmodium falciparum Malaria

1968 • 40 citations

THE DIAGNOSTIC VALUE OF THE PLACENTAL BLOOD FILM IN ÆSTIVO-AUTUMNAL MALARIA

1915 • 39 citations

Malaria‐Induced Immune Thrombocytopenia

1984 • 38 citations

A CONTRIBUTION TO THE MICROSCOPICAL HISTOLOGY OF MALARIA,

1917 • 37 citations

Studies on Malignant Malaria in Macedonia

1920 • 37 citations

EFFECTIVENESS OF SMS 201-995, A SYNTHETIC, LONG-ACTING SOMATOSTATIN ANALOGUE, IN TREATMENT OF QUININE-INDUCED HYPERINSULINAEMIA

1986 • 36 citations

Factors contributing to the development of cerebral malaria. II. Endotoxin.

1985 • 35 citations

Serum Biochemical Changes in Malarial Infections in Men, Chimpanzees and Mice

1966 • 31 citations

An Investigation on Fatal Cases of Pernicious Malaria Caused by Plasmodium Falciparum in Macedonia

1919 • 30 citations

Death Due to Estivo-Autumnal Malaria

1944 • 30 citations

Malaria Hepatitis

1967 • 30 citations

Cerebral malaria — the quest for suitable experimental models in parasitic diseases of man

1976 • 29 citations

Part 2: Tropical Asia

1981 • 29 citations

Limitations of xylose tolerance test as a screening procedure in childhood coeliac disease.

1975 • 28 citations

Renal Failure Due to Acute Glomerulonephritis During Falciparum Malaria: Case Report

1972 • 27 citations

The Artificial Kidney in Malaria and Blackwater Fever

1962 • 27 citations

Pulmonary oedema in the falciparum malaria.

1979 • 27 citations

Cerebral Malaria

1974 • 24 citations

Pathological lesions produced in the brain by kallikrein (kininogenase) inMacaca mulatta, infected withPlasmodium knowlesi

1970 • 24 citations

Hypoglycaemia in falciparum malaria

1983 • 23 citations

The Cerebral Form of Malaria.

1944 • 23 citations

Renal involvement in malaria

1970 • 22 citations

Pulmonary Function Studies inPlasmodium falciparumMalaria1–4

1972 • 22 citations

Electron microscopy of cerebral malaria in golden hamsters (Mesocricetus auratus) infected with Plasmodium berghei

1979 • 22 citations

The effects of malaria on the heart

1946 • 21 citations

Coagulation Activation and Hyperviscosity in Infection

1979 • 20 citations

Medical Shock in the Pathogenesis of Algid Malaria 1

1946 • 17 citations

Malaria and Malarial Diseases

1885 • 17 citations

C-reactive protein in Gambian Africans with special reference to P. falciparum malaria

1971 • 15 citations

The Pulmonary Manifestations in Malaria

1919 • 15 citations

Induction of labor and abortion with quinine infusion in intrauterine fetal deaths

1968 • 13 citations

HEPATITIS OF MALARIAL ORIGIN

1954 • 12 citations

Malarial acute renal failure.

1983 • 12 citations

Attempts to Induce Blackwater Fever Experimentally

1947 • 11 citations

TREATMENT OF BLACKWATER FEVER WITH PREDNISONE

1956 • 10 citations

Hypoglycaemia in falciparum malaria--an unusual manifestation.

1985 • 8 citations

Effect of Islet-Activating Protein (IAP), Purified from the Culture Medium of Bordetella pertussis, on the Secretion of Immunoreactive Insulin and Glucagon in Normal, Alloxan-Treated, and Depancreatized Dogs

1981 • 8 citations

Malaria in pregnancy.

1972 • 7 citations

LABORATORY STUDIES IN TROPICAL MEDICINE

1923 • 6 citations

Studies in Blackwater Fever

1915 • 5 citations

Laboratory Studies in Tropical Medicine

1923 • 3 citations

Acute respiratory distress syndrome in an adult during pernicious malaria. Case report.

1980 • 3 citations

Complications Pulmonaires De La Malaria A Propos De Deux Cas

1984 • 2 citations

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