Complement Peptides C3a- and C5a-Induced Mediator Release from Dissociated Human Skin Mast Cells

STUDIES ON THE MECHANISMS OF HYPERSENSITIVITY PHENOMENA

1964 • 663 citations

Demonstration of specific C5a receptor on intact human polymorphonuclear leukocytes.

1978 • 512 citations

Anaphylatoxin inactivator of human plasma: its isolation and characterization as a carboxypeptidase

1970 • 509 citations

THE DERIVATION OF TWO DISTINCT ANAPHYLATOXIN ACTIVITIES FROM THE THIRD AND FIFTH COMPONENTS OF HUMAN COMPLEMENT

1968 • 460 citations

ISOLATION OF A FRAGMENT (C3a) OF THE THIRD COMPONENT OF HUMAN COMPLEMENT CONTAINING ANAPHYLATOXIN AND CHEMOTACTIC ACTIVITY AND DESCRIPTION OF AN ANAPHYLATOXIN INACTIVATOR OF HUMAN SERUM

1969 • 430 citations

G protein activation: a receptor-independent mode of action for cationic amphiphilic neuropeptides and venom peptides

1990 • 428 citations

Tachykinin antagonists

1994 • 356 citations

Release of histamine from rat mast cells by the complement peptides C3a and C5a.

1975 • 290 citations

Human skin mast cells: their dispersion, purification, and secretory characterization.

1987 • 274 citations

Human mast cell heterogeneity: Histamine release from mast cells dispersed from skin, lung, adenoids, tonsils, and colon in response to IgE-dependent and nonimmunologic stimuli

1988 • 258 citations

Basophils in bronchial asthma with reference to reagin‐type allergy

1973 • 237 citations

Characterization of neuropeptide‐induced histamine release from human dispersed skin mast cells

1988 • 216 citations

Interleukin 3-dependent mediator release in basophils triggered by C5a.

1989 • 207 citations

COMPLEMENT AS A MEDIATOR OF INFLAMMATION

1967 • 193 citations

Differential release of histamine and eicosanoids from human skin mast cells activated by IgE‐dependent and non‐immunological stimuli

1989 • 165 citations

Characterization of histamine secretion from mechanically dispersed human lung mast cells: effects of anti-IgE, calcium ionophore A23187, compound 48/80, and basic polypeptides.

1982 • 163 citations

Interleukin 3 and granulocyte/macrophage-colony-stimulating factor render human basophils responsive to low concentrations of complement component C3a.

1990 • 160 citations

Human mast cell carboxypeptidase. Selective localization to MCTC cells.

1991 • 159 citations

Isolation of three separate anaphylatoxins from complement-activated human serum

1981 • 134 citations

Role of cell surface contact in the kinetics of superoxide production by granulocytes.

1983 • 126 citations

Complement-Mediated Release of Histamine from Human Leukocytes

1975 • 125 citations

On the actions of substance P, somatostatin, and vasoactive intestinal polypeptide on rat peritoneal mast cells and in human skin

1985 • 117 citations

Gross and ultrastructural observations on lesions produced by intradermal injection of human C3a in man.

1970 • 111 citations

Isolation of three separate anaphylatoxins from complement-activated human serum

1981 • 104 citations

Effects of ADP-ribosylation of GTP-binding protein by pertussis toxin on immunoglobulin E-dependent and -independent histamine release from mast cells and basophils.

1987 • 104 citations

Complement-induced histamine release from human basophils. II. Mechanism of the histamine release reaction.

1976 • 101 citations

Neuropeptide-Induced Secretion from Human Skin Mast Cells

1991 • 100 citations

Differential effects of the complement peptides, C5a and C5a des Arg on human basophil and lung mast cell histamine release.

1988 • 100 citations

Studies of human C5a as a mediator of inflammation in normal human skin.

1985 • 95 citations

Cutaneous responses to human C 3 anaphylatoxin in man.

1972 • 92 citations

Role of the N-terminal arginine in the histamine-releasing activity of substance P, bradykinin and related peptides

1989 • 83 citations

Complement-Induced Histamine Release from Human Basophils

1976 • 70 citations

The effect of pertussis toxin on mediator release from human basophils.

1987 • 65 citations

Characterization of the plasma membrane bound GTPase from rabbit neutrophils. I. Evidence for an Ni-like protein coupled to the formyl peptide, C5a, and leukotriene B4 chemotaxis receptors.

1986 • 57 citations

Human mast cell carboxypeptidase.

1990 • 49 citations

Methotrexate Inhibits the Human C5a-Induced Skin Response in Patients With Psoriasis

1987 • 48 citations

Histamine release induced by Arg-Pro-Lys-Pro(CH2)11CH3 from rat peritoneal mast cells.

1987 • 46 citations

A direct in vivo comparison of the inflammatory properties of human C5a and C5a des Arg in human skin.

1988 • 38 citations

Platelet Activation: a New Biological Activity of Guinea‐pig C3a Anaphylatoxin

1978 • 37 citations

Neutral proteases as indicators of human mast cell heterogeneity.

1990 • 28 citations

Complement Activation Requirements for Histamine Release from Human Leukocytes: Influence of Purified C3a<sub>hu</sub> and C5a<sub>hu</sub> on Histamine Release

1981 • 28 citations

The Effect of Human Anaphylatoxins and Neutrophils on Histamine Release from Isolated Human Skin Mast Cells

1992 • 23 citations

C5a, Cutaneous Mast Cells, and Inflammation: In Vitro and In Vivo Studies in a Murine Model

1991 • 18 citations

Inflammatory properties of human C5a and C5a des Arg/ in mast cell-depleted human skin

1989 • 17 citations

Human Skin Mast Cell Carboxypeptidase: Functional Characterization, cDNA Cloning, and Genealogy

1992 • 17 citations

Circulating immune complexes in dermatologic disease

1981 • 11 citations

Circulating Immune Complexes in Dermatologic Disease

1983 • 9 citations

Inflammatory Properties of Human C5a and C5a des Arg/ in Mast Cell-Depleted Human Skin.

1989 • 5 citations

The role of complement in urticaria and angioedema.

1981 • 3 citations