Dissociation of proto‐oncogene induction from growth response in normal human fibroblasts

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

Virus interference. I. The interferon

1957 • 3,331 citations

Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene

1984 • 3,150 citations

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

1983 • 2,350 citations

Ribonucleic acid isolated by cesium chloride centrifugation

1974 • 2,263 citations

Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene

1985 • 1,836 citations

Induction of c-fos gene and protein by growth factors precedes activation of c-myc

1984 • 1,463 citations

Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and protein

1984 • 949 citations

Biochemistry of Interferons and Their Actions

1982 • 868 citations

Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma.

1983 • 764 citations

c-fos protein can induce cellular transformation: A novel mechanism of activation of a cellular oncogene

1984 • 601 citations

Functional role for c-myc in mitogenic response to platelet-derived growth factor

1984 • 578 citations

Induction of β2-interferon by tumor necrosis factor: A homeostatic mechanism in the control of cell proliferation

1986 • 577 citations

Repression of c- fos Transcription and an Altered Genetic Program in Senescent Human Fibroblasts

1990 • 478 citations

Expression of the c- fos Gene and of an fos -Related Gene Is Stimulated by Platelet-Derived Growth Factor

1984 • 445 citations

Quantitative studies on viral interference in suspended L cells

1962 • 395 citations

Microinjected c- myc as a Competence Factor

1985 • 361 citations

Close link between reduction of c-myc expression by interferon and G0/G1 arrest

1985 • 358 citations

Interferon-activated genes

1986 • 301 citations

c-myc gene is transcribed at high rate in G0-arrested fibroblasts and is post-transcriptionally regulated in response to growth factors

1985 • 300 citations

A Cytokine Network in Human Diploid Fibroblasts: Interactions of β-Interferons, Tumor Necrosis Factor, Platelet-Derived Growth Factor, and Interleukin-1

1987 • 261 citations

A unique set of polypeptides is induced by γ interferon in addition to those induced in common with α and β interferons

1983 • 234 citations

Autocrine β-related interferon controls c-myc suppression and growth arrest during hematopoietic cell differentiation

1986 • 206 citations

A cytokine network in human diploid fibroblasts: interactions of beta-interferons, tumor necrosis factor, platelet-derived growth factor, and interleukin-1.

1987 • 175 citations

Interferon regulates c-myc gene expression in Daudi cells at the post-transcriptional level.

1985 • 149 citations

Endogenous Regulation of Macrophage Proliferative Expansion by Colony-Stimulating Factor-Induced Interferon

1984 • 144 citations

In vivo antitumor activity of multiple injections of recombinant interleukin 2, alone and in combination with three different types of recombinant interferon, on various syngeneic murine tumors.

1988 • 131 citations

Increased human red cell cation passive permeability below 12 °C

1980 • 131 citations

Fibroblast interferon induces synthesis of four proteins in human fibroblast cells.

1979 • 118 citations

Interferon-induced gene expression in wild-type and interferon-resistant human lymphoblastoid (Daudi) cells

1986 • 85 citations

Transcriptional activation of immunoglobulin α heavy-chain genes by translocation of the c-myc oncogene

1983 • 84 citations

Prior Chronic Sun Exposure Decreases the Lifespan of Human Skin Fibroblasts in Vitro

1980 • 68 citations

Progress toward therapeutic application of interferons, 1979–1983

1984 • 63 citations

Induction of unique mRNAs by human interferons.

1982 • 59 citations

Effects of Alpha and Beta Interferons on Cultured Human Keratinocytes

1985 • 53 citations

Interferon nomenclature.

1980 • 49 citations

beta-Interferon alters the pattern of proteins secreted from quiescent and platelet-derived growth factor-treated BALB/c-3T3 cells.

1985 • 48 citations

Partial reversion of the transformed phenotype of murine sarcoma virus-transformed cells in the presence of interferon: A possible mechanism for the anti-tumour effect of interferon

1981 • 47 citations

c-myc and c-fos expression during interferon-alpha therapy for hairy cell leukemia

1986 • 36 citations

Cell cycle perturbations in normal and transformed fibroblasts caused by detachment from the substratum

1983 • 36 citations

Effects of epidermal growth factor and platelet-derived growth factor on c-fos and c-myc mRNA levels in normal human fibroblasts

1987 • 34 citations

Normal human epidermis contains an interferon-like protein.

1986 • 32 citations

Interferons as gene activators: Close linkage of two interferon-activatable murine genes

1988 • 26 citations

The c-fos proto-oncogene in murine 3LL carcinoma clones controls the expression of MHC genes.

1988 • 26 citations

Expression of c-myc oncogene in human fibroblasts during senescence

1986 • 22 citations

Influence of Increased Extracellular Calcium Concentration and Donor Age on Density-Dependent Growth Inhibition of Human Fibroblasts

1986 • 21 citations

Posttranscriptional changes in growth factor-inducible gene regulation caused by antiproliferative interferons.

1990 • 20 citations

Interferon-Mediated Regulation of myc and Ki-ras Oncogene Expression in Long-Term-Treated Murine Viral Transformed Cells

1985 • 18 citations

Comparison of combinations of interferons with tumor specific and nonspecific monoclonal antibodies as therapy for murine B- and T-cell lymphomas.

1988 • 12 citations

A role for T cell helper factors in antibody responses to "T-independent" antigens.

1982 • 8 citations

Influence of interferon-alpha on the expression of cellular oncogenes in primary chronic lymphocytic leukemia cells.

1988 • 7 citations

Effects of interferons alpha,beta,gamma alone or in combination on the phenotype of human colon carcinoma cells.

1988 • 7 citations

The pathobiology of proto-oncogenes.

1986 • 1 citations