Use of Herpesvirus saimiri-immortalized macaque CD4+ T cell clones as stimulators and targets for assessment of CTL responses in macaque/AIDS models

Quantitation of HIV-1-Specific Cytotoxic T Lymphocytes and Plasma Load of Viral RNA

1998 • 1,426 citations

In vitro mutagenesis identifies a region within the envelope gene of the human immunodeficiency virus that is critical for infectivity

1988 • 754 citations

Major expansion of CD8+ T cells with a predominant Vβ usage during the primary immune response to HIV

1994 • 611 citations

A chimeric simian/human immunodeficiency virus expressing a primary patient human immunodeficiency virus type 1 isolate env causes an AIDS-like disease after in vivo passage in rhesus monkeys

1996 • 501 citations

Cytotoxic T cell responses to multiple conserved HIV epitopes in HIV-resistant prostitutes in Nairobi.

1998 • 431 citations

Decay Kinetics of Human Immunodeficiency Virus-Specific Effector Cytotoxic T Lymphocytes after Combination Antiretroviral Therapy

1999 • 350 citations

Stable growth transformation of human T lymphocytes by herpesvirus saimiri.

1992 • 299 citations

A New Look at T Cells

1998 • 269 citations

Chimeric simian/human immunodeficiency virus that causes progressive loss of CD4+ T cells and AIDS in pig-tailed macaques

1996 • 249 citations

An env gene derived from a primary human immunodeficiency virus type 1 isolate confers high in vivo replicative capacity to a chimeric simian/human immunodeficiency virus in rhesus monkeys

1996 • 238 citations

Induction of vigorous cytotoxic T-lymphocyte responses by live attenuated simian immunodeficiency virus

1997 • 142 citations

Epstein-Barr virus and the B cell: that's all it takes

1996 • 125 citations

Strong Human Immunodeficiency Virus (HIV)-Specific Cytotoxic T-Lymphocyte Activity in Sydney Blood Bank Cohort Patients Infected withnef-Defective HIV Type 1

1999 • 104 citations

Immortalization of human T cell clones by Herpesvirus saimiri. Signal transduction analysis reveals functional CD3, CD4, and IL-2 receptors.

1993 • 81 citations

Oral Immunization of Macaques with Attenuated Vaccine Virus Induces Protection against Vaginally Transmitted AIDS

1998 • 76 citations

Distinct Recognition of Non-Clade B Human Immunodeficiency Virus Type 1 Epitopes by Cytotoxic T Lymphocytes Generated from Donors Infected in Africa

1999 • 74 citations

Herpesvirus saimiri Transformed Human T Cell Lines: A Permissive System for Human Immunodeficiency Viruses

1993 • 34 citations

Antigenic Variation of Molecularly Cloned SIVmac239 during Persistent Infection in a Rhesus Macaque

1993 • 27 citations

Herpesvirus saimiri-transformed human CD4+ T cells can provide polyclonal B cell help via the CD40 ligand as well as the TNF-alpha pathway and through release of lymphokines.

1996 • 27 citations

Growth Transformation of Antigen-Specific T Cell Lines from Rhesus Monkeys byHerpesvirus saimiri

1997 • 25 citations

A Simple Method to Selectively Expand HIV-1 Specific Cytotoxic T Lymphocytes in Vitro

1995 • 12 citations

Herpesvirus Saimiri-Transformed Human CD4⁺T-Cell Lines: an Efficient Target Cell System for the Analysis of Human Immunodeficiency Virus-Specific Cytotoxic CD8⁺T-Lymphocyte Activity

1998 • 9 citations