Local Release of Highly Loaded Antibodies from Functionalized Nanoporous Support for Cancer Immunotherapy

Triblock Copolymer Syntheses of Mesoporous Silica with Periodic 50 to 300 Angstrom Pores

1998 • 11,268 citations

Enhancement of Antitumor Immunity by CTLA-4 Blockade

1996 • 3,585 citations

Functionalized Monolayers on Ordered Mesoporous Supports

1997 • 1,555 citations

CTLA-4: new insights into its biological function and use in tumor immunotherapy

2002 • 923 citations

Monoclonal antibodies against the 4-1BB T-cell activation molecule eradicate established tumors

1997 • 886 citations

Ipilimumab (Anti-CTLA4 Antibody) Causes Regression of Metastatic Renal Cell Cancer Associated With Enteritis and Hypophysitis

2007 • 673 citations

Influence of pore size of MCM-41 matrices on drug delivery rate

2004 • 544 citations

Entrapping Enzyme in a Functionalized Nanoporous Support

2002 • 515 citations

Catalytic Activity in Organic Solvents and Stability of Immobilized Enzymes Depend on the Pore Size and Surface Characteristics of Mesoporous Silica

2000 • 482 citations

Mesoporous Silicate Sequestration and Release of Proteins

1999 • 349 citations

Mechanistic and Structural Features of Protein Adsorption onto Mesoporous Silicates

2002 • 264 citations

Enzyme immobilisation using siliceous mesoporous molecular sieves

2001 • 189 citations

Gene therapy for cancer using single-chain Fv fragments specific for 4-1BB

2002 • 162 citations

Molecular Assembly in Ordered Mesoporosity: A New Class of Highly Functional Nanoscale Materials

2000 • 130 citations

Characterization of functionalized nanoporous supports for protein confinement

2006 • 111 citations

Ordered Hierarchical Porous Materials: Towards Tunable Size- and Shape-Selective Microcavities in Nanoporous Channels The Pacific Northwest National Laboratory is operated by Battelle for the U.S. Department of Energy under Contract DE-AC06-76RL0 1830. This work is supported by the Office of Basic Energy Sciences, Division of Materials Sciences, of the U.S. Department of Energy.

2000 • 75 citations

Probing mechanisms for enzymatic activity enhancement of organophosphorus hydrolase in functionalized mesoporous silica

2009 • 34 citations

Vaccines to treat cancer‐an old approach whose time has arrived

2007 • 9 citations