Polyphosphoinositide synthesis in platelets stimulated with low concentrations of thrombin is enhanced before the activation of phospholipase C

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

INOSITOL TRISPHOSPHATE AND DIACYLGLYCEROL: TWO INTERACTING SECOND MESSENGERS

1987 • 3,302 citations

Release of Ca2+ from a nonmitochondrial intracellular store in pancreatic acinar cells by inositol-1,4,5-trisphosphate

1983 • 2,596 citations

Inositol phospholipids and cell surface receptor function

1975 • 2,458 citations

PDGF-dependent tyrosine phosphorylation stimulates production of novel polyphosphoinositides in intact cells

1989 • 933 citations

Specific interaction between phosphatidylinositol 4,5-bisphosphate and profilactin

1985 • 824 citations

Selective assay of monomeric and filamentous actin in cell extracts, using inhibition of deoxyribonuclease I

1978 • 564 citations

Thrombin-induced phosphodiesteratic cleavage of phosphatidylinositol bisphosphate in human platelets.

1983 • 394 citations

Phosphoinositides in mitogenesis: Neomycin inhibits thrombin-stimulated phosphoinositide turnover and initiation of cell proliferation

1985 • 332 citations

Isoform-specific induction of actin reorganization by platelet-derived growth factor suggests that the functionally active receptor is a dimer.

1989 • 191 citations

Specificity of the interaction between phosphatidylinositol 4,5‐bisphosphate and the profilin:actin complex

1988 • 168 citations

Evidence that the phosphatidylinositol cycle is linked to cell motility

1988 • 131 citations

Characterization of platelet extracts before and after stimulation with respect to the possible role of profilactin as microfilament precursor

1981 • 100 citations

Tight coupling of thrombin-induced acid hydrolase secretion and phosphatidate synthesis to receptor occupancy in human platelets

1984 • 85 citations

Neomycin inhibits inositol phosphate formation in human platelets stimulated by thrombin but not other agonists

1986 • 42 citations

Stimulation of phosphate uptake in human platelets by thrombin and collagen. Changes in specific 32P labeling of metabolic ATP and polyphosphoinositides.

1987 • 22 citations