Prognostic values of matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 expression in bladder cancer

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1979 • 22,482 citations

TNM Classification of Malignant Tumours

1987 • 16,209 citations

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

1991 • 2,774 citations

A matrix metalloproteinase expressed on the surface of invasive tumour cells

1994 • 2,561 citations

Metastatic potential correlates with enzymatic degradation of basement membrane collagen

1980 • 1,778 citations

Tumor invasion and metastases--role of the extracellular matrix: Rhoads Memorial Award lecture.

1986 • 1,408 citations

H-ras oncogene-transformed human bronchial epithelial cells (TBE-1) secrete a single metalloprotease capable of degrading basement membrane collagen.

1988 • 1,050 citations

Chapter 1: Interferons (IFNs)

1986 • 793 citations

Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction.

1990 • 736 citations

Loss of basement membrane components by invasive tumors but not by their benign counterparts.

1983 • 497 citations

Antisense RNA-Induced Reduction in Murine TIMP Levels Confers Oncogenicity on Swiss 3T3 Cells

1989 • 459 citations

Tissue inhibitor of metalloproteinases-2 (TIMP-2) mRNA expression in tumor cell lines and human tumor tissues.

1990 • 428 citations

Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion.

1993 • 428 citations

Matrix metalloprotease 2 (MMP-2) and matrix metalloprotease 9 (MMP-9) type IV collagenases in colorectal cancer.

1996 • 325 citations

Degradation of basement membrane type IV collagen and lung subendothelial matrix by rat mammary adenocarcinoma cell clones of differing metastatic potentials.

1987 • 315 citations

Inhibition by human recombinant tissue inhibitor of metalloproteinases of human amnion invasion and lung colonization by murine B16-F10 melanoma cells.

1988 • 312 citations

Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro.

1996 • 278 citations

Expression of membrane-type matrix metalloproteinase in human gastric carcinomas

1995 • 267 citations

Activation of the precursor of gelatinase A/72 kda type IV collagenase/MMP‐2 in lung carcinomas correlates with the expression of membrane‐type matrix metalloproteinase (MT‐MMP) and with lymph node metastasis

1995 • 267 citations

Increased gelatinase A (MMP-2) and cathepsin B activity in invasive tumor regions of human colon cancer samples.

1994 • 242 citations

Membrane-type matrix metalloproteinase 1 is a gelatinolytic enzyme and is secreted in a complex with tissue inhibitor of metalloproteinases 2.

1996 • 232 citations

High levels of tissue inhibitor of metalloproteinase-2 (TIMP-2) expression are associated with poor outcome in invasive bladder cancer.

1996 • 188 citations

Enhanced production of matrix metalloproteinases and activation of matrix metalloproteinase 2 (gelatinase A) in human gastric carcinomas

1996 • 170 citations

High level of MT-MMP expression is associated with invasiveness of cervical cancer cells

1996 • 165 citations

Overexpression of tissue inhibitor of metalloproteinases-2 retroviral-mediated gene transfer in vivo inhibits tumor growth and invasion.

1996 • 134 citations

Processing of a precursor of 72-kilodalton type IV collagenase/gelatinase A by a recombinant membrane-type 1 matrix metalloproteinase.

1996 • 110 citations

Over‐expression of tissue inhibitor of matrix metalloproteinases (TIMP1 and TIMP2) suppresses extravasation of pulmonary metastasis of a rat bladder carcinoma

1995 • 69 citations

gelatinase A/TIMP‐2 imbalance in lymph‐node‐positive breast carcinomas, as measured by RT‐PCR

1995 • 65 citations

Prognosis of Transitional Cell Bladder Cancer: A Multivariate Prognostic Score for Improved Prediction

1991 • 58 citations

Gelatinase A (MMP-2) and Its mRNA Detected in Both Neoplastic and Stromal Cells of Tumors with Different Invasive and Metastatic Properties

1994 • 42 citations

GENE EXPRESSIONS OF TYPE IV COLLAGENASE AND TISSUE INHIBITOR OF METALLOPROTEINASES (TIMP) IN HUMAN BLADDER CANCERS

1993 • 14 citations