Interleukin‐12 Antagonist Activity of Mouse Interleukin‐12 p40 Homodimer in Vitro and in Vivo

Development of T _H 1 CD4 ⁺ T Cells Through IL-12 Produced by Listeria -Induced Macrophages

1993 • 3,140 citations

Production of natural killer cell stimulatory factor (interleukin 12) by peripheral blood mononuclear cells.

1992 • 1,168 citations

Interleukin-12: a cytokine produced by antigen-presenting cells with immunoregulatory functions in the generation of T-helper cells type 1 and cytotoxic lymphocytes

1994 • 1,066 citations

Recombinant interleukin 12 cures mice infected with Leishmania major.

1993 • 776 citations

Resolution of cutaneous leishmaniasis: interleukin 12 initiates a protective T helper type 1 immune response.

1993 • 738 citations

Cloning and expression of murine IL-12.

1992 • 474 citations

Mouse interleukin‐12 (IL‐12) p40 homodimer: a potent IL‐12 antagonist

1995 • 441 citations

Administration of recombinant IL-12 to normal mice enhances cytolytic lymphocyte activity and induces production of IFN-γ in vivo

1994 • 373 citations

B7 and interleukin 12 cooperate for proliferation and interferon gamma production by mouse T helper clones that are unresponsive to B7 costimulation.

1994 • 367 citations

Expression cloning of a human IL-12 receptor component. A new member of the cytokine receptor superfamily with strong homology to gp130.

1994 • 309 citations

IL-12 receptor. II. Distribution and regulation of receptor expression.

1992 • 298 citations

Interleukin 12 is produced in vivo during endotoxemia and stimulates synthesis of gamma interferon

1994 • 223 citations

Cloning and characterization of a mouse IL-12 receptor-beta component.

1995 • 155 citations

IL‐12‐Deficient Mice Are Defective but Not Devoid of Type 1 Cytokine Responses

1996 • 115 citations

Role of IL-12 in human B lymphocyte proliferation and differentiation.

1995 • 89 citations

Characterization of anti-mouse IL-12 monoclonal antibodies and measurement of mouse IL-12 by ELISA

1996 • 38 citations

IL12 receptors and receptor antagonists

1995 • 27 citations