Cholesterol-mediated Neurite Outgrowth Is Differently Regulated between Cortical and Hippocampal Neurons

Lipid rafts and signal transduction

2000 • 6,079 citations

The establishment of polarity by hippocampal neurons in culture

1988 • 1,820 citations

Tangles and plaques in nondemented aging and ?preclinical? Alzheimer's disease

1999 • 1,648 citations

CNS Synaptogenesis Promoted by Glia-Derived Cholesterol

2001 • 1,622 citations

Frequency of Stages of Alzheimer-Related Lesions in Different Age Categories

1997 • 1,599 citations

Cholesterol depletion inhibits the generation of β-amyloid in hippocampal neurons

1998 • 1,139 citations

Simvastatin strongly reduces levels of Alzheimer's disease β-amyloid peptides Aβ42 and Aβ40 in vitro and in vivo

2001 • 1,083 citations

Characterization of caveolin-rich membrane domains isolated from an endothelial-rich source: implications for human disease.

1994 • 912 citations

Essential role for cholesterol in synaptic plasticity and neuronal degeneration

2001 • 279 citations

Cholesterol and Alzheimer’s disease

2001 • 258 citations

Netrin requires focal adhesion kinase and Src family kinases for axon outgrowth and attraction

2004 • 257 citations

Neuronal polarity: Essential role of protein–lipid complexes in axonal sorting

1998 • 222 citations

Apolipoprotein E (ApoE) Isoform-dependent Lipid Release from Astrocytes Prepared from Human ApoE3 and ApoE4 Knock-in Mice

2002 • 207 citations

Altered Cholesterol Metabolism in Niemann-Pick Type C1 Mouse Brains Affects Mitochondrial Function

2005 • 202 citations

Glial Lipoproteins Stimulate Axon Growth of Central Nervous System Neurons in Compartmented Cultures

2004 • 185 citations

Deregulation of cdk5, Hyperphosphorylation, and Cytoskeletal Pathology in the Niemann–Pick Type C Murine Model

2002 • 182 citations

Neurofibrillary tangles in Niemann-Pick disease type C

1995 • 179 citations

A Regulatory Role for Sphingolipids in Neuronal Growth

1995 • 157 citations

Inhibition of Cholesterol Production but Not of Nonsterol Isoprenoid Products Induces Neuronal Cell Death

1999 • 142 citations

Cholesterol‐dependent modulation of dendrite outgrowth and microtubule stability in cultured neurons

2001 • 129 citations

Cholesterol‐dependent modulation of tau phosphorylation in cultured neurons

2001 • 128 citations

Maturation of the axonal plasma membrane requires upregulation of sphingomyelin synthesis and formation of protein-lipid complexes

1999 • 128 citations

Phosphorylation of DCC by Fyn mediates Netrin-1 signaling in growth cone guidance

2004 • 120 citations

Trafficking of Cholesterol from Cell Bodies to Distal Axons in Niemann Pick C1-deficient Neurons

2003 • 104 citations

Site-specific Phosphorylation of Tau Accompanied by Activation of Mitogen-activated Protein Kinase (MAPK) in Brains of Niemann-Pick Type C Mice

2001 • 97 citations

Lipid-dependent Recruitment of Neuronal Src to Lipid Rafts in the Brain

2003 • 92 citations

Modulation of Amyloid Precursor Protein Cleavage by Cellular Sphingolipids

2004 • 82 citations

Transmembrane phosphoprotein Cbp senses cell adhesion signaling mediated by Src family kinase in lipid rafts

2003 • 73 citations

Axonal Regeneration, but Not Myelination, Is Partially Dependent on Local Cholesterol Reutilization in Regenerating Nerve

2000 • 30 citations

Independent accumulations of tau and amyloid β-protein in the human entorhinal cortex

2005 • 25 citations