Chemical Evidence for Production of Hydroxyl Radicals During Microsomal Electron Transfer

The Biology of Oxygen Radicals

1978 • 3,361 citations

Pharmacological implications of microsomal enzyme induction.

1967 • 2,883 citations

Fenton's reagent revisited

1975 • 2,778 citations

The cellular production of hydrogen peroxide

1972 • 1,526 citations

A compilation of specific bimolecular rate constants for the reactions of hydrated electrons, hydrogen atoms and hydroxyl radicals with inorganic and organic compounds in aqueous solution

1967 • 981 citations

The Generation of Hydrogen Peroxide, Superoxide Radical, and Hydroxyl Radical by 6-Hydroxydopamine, Dialuric Acid, and Related Cytotoxic Agents

1974 • 894 citations

Superoxide‐dependent production of hydroxyl radical catalyzed by iron—EDTA complex

1978 • 876 citations

Hepatic Microsomal Ethanol-oxidizing System

1970 • 824 citations

Superoxide‐dependent formation of hydroxyl radicals in the presence of iron chelates

1978 • 748 citations

A Mechanism for the Production of Ethylene from Methional

1970 • 668 citations

Evidence that Peroxidation of Lysosomal Membranes Is Initiated by Hydroxyl Free Radicals Produced during Flavin Enzyme Activity

1973 • 663 citations

Hepatic Microsomal Ethanol Oxidation

1972 • 603 citations

Superoxide and superoxide dismutases

1993 • 518 citations

The oxidation of drugs by liver microsomes: on the role of TPNH and oxygen.

1957 • 399 citations

Studies on hydroperoxide-dependent substrate hydroxylation by purified liver microsomal cytochrome P-450

1976 • 339 citations

Reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent formation and breakdown of hydrogen peroxide during mixed function oxidation reactions in liver microsomes

1975 • 330 citations

Evidence for hydroxyl radical production by human neutrophils.

1977 • 257 citations

A new spectral intermediate associated with cytochrome P-450 function in liver microsomes

1971 • 240 citations

Evidence for superoxide generation by NADPH-cytochrome C reductase of rat liver microsomes

1972 • 193 citations

COMPARATIVE STUDY OF OXIDATION OF NUCLEIC ACID COMPONENTS BY HYDROXYL RADICALS, SINGLET OXYGEN AND SUPEROXIDE ANION RADICALS

1978 • 193 citations

Hydrogen peroxide formation and stoichiometry of hydroxylation reactions catalyzed by highly purified liver microsomal cytochrome P-450

1977 • 187 citations

Ethylene formation from methional

1978 • 156 citations

701. Electron spin resonance studies of oxidation. Part II. Aliphatic acids and substituted acids

1964 • 152 citations

Evidence for hydroxyl radical generation by human Monocytes.

1977 • 152 citations

Hydroxyl radical production involved in lipid peroxidation of rat liver microsomes

1977 • 151 citations

CURRENT CONCEPTS CONCERNING RADIOPROTECTIVE AND CRYOPROTECTIVE PROPERTIES OF DIMETHYL SULFOXIDE IN CELLULAR SYSTEMS*

1975 • 123 citations

Kinetics of the Decomposition of Hydrogen Peroxide Catalyzed by Ferric Ethylenediaminetetraacetate Complex

1975 • 112 citations

Destruction of sympathetic nerve terminals by 6-hydroxydopamine: protection by 1-phenyl-3-(2-thiazolyl)-2-thiourea, diethyldithiocarbamate, methimazole, cysteamine, ethanol and n-butanol.

1976 • 110 citations

The effect of dimethylsulfoxide and other hydroxyl radical scavengers on the oxidation of ethanol by rat liver microsomes

1977 • 101 citations

Role of vitamin E in glutathione-induced oxidant stress: methemoglobin, lipid peroxidation, and hemolysis

1977 • 100 citations

Effect of hydroxyl radical scavengers on microsomal oxidation of alcohols and on associated microsomal reactions

1978 • 82 citations

Further Studies on Ethylene Formation from α-Keto-γmethylthiobutyric Acid or β-Methylthiopropionaldehyde by Peroxidase in the Presence of Sulfite and Oxygen

1969 • 77 citations

Trapping of Short-Lived Free Radicals as Nitroxide Radicals Detectable by ESR Spectroscopy. The Radicals Formed in the Reaction between OH-Radicals and Some Sulphoxides and Sulphones.

1969 • 72 citations

The reaction of superoxide radical with iron complexes of EDTA studied by pulse radiolysis

1977 • 70 citations

STUDIES ON THE NADPH OXIDASE REACTION OF NADPH‐CYTOCHROME C REDUCTASE. I. THE ROLE OF SUPEROXIDE ANION*

1973 • 57 citations

The effect of pargyline and other monoamine oxidase inhibitors on blood acetaldehyde levels in ethanol-intoxicated mice.

1976 • 47 citations

Reactions of oxygen radical species with methional: A pulse radiolysis study

1976 • 45 citations

Ethanol metabolism by a transplantable hepatocellular carcinoma. Role of microsomes and mitochondria.

1976 • 18 citations

Free radicals in NADPH-microsomes-triphenyltetrazolium chloride system as evidenced by initiation of sulfite oxidation

1967 • 17 citations

Cytochrome P-450: An Oxygenase, Peroxidase and Oxidase

1975 • 11 citations