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Present status of drugs as teratogens in man

Data up to Jan 2025

Published1973
Citations89
References99

Total Citations Per Year

Abstract

References (99)

Adenocarcinoma of the Vagina

1971 • 2,464 citations

Surgery of urethral stricture.

1948 • 429 citations

Therapeutic Abortions with a Folic Acid Antagonist, 4-Aminopteroylglutamic Acid (4-Amino P. G. A.) Administered by the Oral Route

1952 • 402 citations

Associations between Drugs Administered during Pregnancy and Congenital Abnormalities of the Fetus

1971 • 359 citations

Production of congenital defects in the off-spring of pregnant mice treated with cortisone; progress report.

1951 • 354 citations

PRODUCTION OF CONGENITAL DEFECTS IN THE OFFSPRING OF PREGNANT MICE TREATED WITH CORTISONE

1951 • 340 citations

Vaginal Cancer after Maternal Treatment with Synthetic Estrogens

1971 • 337 citations

Methotrexate-induced congenital malformations

1968 • 319 citations

Pharmacokinetics of Salicylate Elimination in Man

1965 • 283 citations

CYTOTOXIC DRUGS IN PREGNANCY

1968 • 250 citations

Steroids During Pregnancy and Possible Fetal Consequences

1960 • 240 citations

MASCULINIZATION OF FEMALE FETUS DUE TO USE OF ORALLY GIVEN PROGESTINS

1960 • 240 citations

B. M. A. and the Green-Paper.

1969 • 233 citations

INSULIN SUPPRESSION

1974 • 226 citations

Anticonvulsant Drugs and Congenital Abnormalities

1968 • 218 citations

Experimental production of congenital malformations in rats by salicylate poisoning.

1959 • 198 citations

The Effects of Androgens on Fetal Sexual Development

1960 • 190 citations

INTRAVENOUS FEEDING

1974 • 188 citations

Congenital Anomalies Probably Induced by Cyclophosphamide

1964 • 184 citations

Attempted Abortion with Aminopterin (4-Amino-Pteroylglutamic Acid)

1959 • 170 citations

EFFECTS OF CANCER CHEMOTHERAPEUTIC AGENTS ON THE HUMAN FETUS

1960 • 165 citations

Trimethadione and human teratogenesis

1970 • 163 citations

Studies on metabolism and identification of the causative agent in aspirin teratogenesis in rats

1971 • 160 citations

Congenital malformations and environmental influences in pregnancy.

1969 • 155 citations

LSD and Genetic Damage

1971 • 144 citations

Relation of dosage and time of administration of diphenylhydantoin to its teratogenic effect in mice

1969 • 141 citations

DANFA PROJECT

1974 • 139 citations

Ciba Foundation Symposium on Congenital Malformations

1961 • 123 citations

Hearing Loss in Infants of Tuberculous Mothers Treated with Streptomycin during Pregnancy

1964 • 118 citations

Fetal Damage Due to ECT, Insulin Coma, Chlorpromazine, or Reserpine

1960 • 105 citations

TRANSPLACENTAL TRANSMISSION OF BUSULFAN (MYLERAN®) IN A MOTHER WITH LEUKEMIA

1960 • 104 citations

Transplacental transmission of busulfan (myleran) in a mother with leukemia. Production of fetal malformation and cytomegaly.

1960 • 103 citations

Possible Teratogenic Effect of Chlorambucil on a Human Fetus

1963 • 100 citations

Embryopathic Activity of Drugs.

1966 • 100 citations

CONGENITAL ANOMALIES DUE TO ATTEMPTED ABORTION WITH 4-AMINOPTEROGLUTAMIC ACID

1956 • 92 citations

Congenital Abnormalities and Anticonvulsant Drugs

1970 • 92 citations

Use of rhesus monkeys in teratological studies.

1971 • 91 citations

MASCULINIZATION OF THE FEMALE INFANT ASSOCIATED WITH ESTROGENIC THERAPY ALONE DURING GESTATION: FOUR CASES*

1959 • 90 citations

Teratology: Principles and techniques

1965 • 84 citations

DEXAMPHETAMINE: A POSSIBLE ENVIRONMENTAL TRIGGER IN CARDIOVASCULAR MALFORMATIONS

1970 • 81 citations

Aminopterin-Induced Fetal Malformation

1968 • 81 citations

Evaluation of the teratogenic effect of meclizine in man

1965 • 79 citations

Salicylate‐Induced Malformations in Mouse Embryos1

1963 • 76 citations

TERATOGENIC INTERACTION OF CHEMICAL AGENTS IN THE RAT

1964 • 75 citations

Maternal Exposure to Potential Teratogens

1967 • 68 citations

An evaluation of aminopterin as an abortifacient

1962 • 64 citations

THE CONTROL OF REPRODUCTION IN RATS WITH THE AID OF ANTIMETABOLITES and EARLY EXPERIENCES WITH ANTIMETABOLITES AS ABORTIFACIENT AGENTS IN MAN

1956 • 61 citations

Imipramine in pregnancy.

1972 • 59 citations

Experimental and Clinical Chemoteratogenesis

1966 • 58 citations

THE TERATOGENIC ACTION OF DRUGS

1963 • 57 citations

Cortisone and Pregnancy*†*Aided by a grant from the National Institutes of Health, United states Public Health Service (RG 2522), to the Rheumatoid Arthritis Research Group of Michael Reese Hospital.†Presented by invitation, at the Seventy-fifth Annual Meeting of the American Gynecologic Society, Hot Springs, Va., May 12 to 14, 1952.

1952 • 55 citations

Imipramine in pregnancy.

1972 • 54 citations

MALFORMATIONS IN MICE INDUCED BY DEXAMPHETAMINE SULPHATE

1965 • 53 citations

Phenmetrazine and Foetal Abnormalities

1962 • 52 citations

Does LSD induce chromosomal damage and malformations? A review of the literature

1972 • 52 citations

Amphetamine ingestion with biliary atresia

1971 • 50 citations

Congenital malformation due to attempted abortion with aminopterin

1962 • 49 citations

Neonatal thrombocytopeniaand congenital malformations associated with administration of tolbutamide to the mother

1970 • 47 citations

Drugs in the first trimester of pregnancy and the fetal life of Homo sapiens

1964 • 45 citations

Congenital Defects among Children Born to Women under Supervision or Treatment for Pulmonary Tuberculosis

1964 • 45 citations

Foetal Defects Following Insulin Coma Therapy in Early Pregnancy

1954 • 40 citations

Congenital Malformations.

1965 • 39 citations

Failure of large doses of ethinyl estradiol to interfere with early embryonic development in the human species

1970 • 37 citations

ARE ANTICONVULSANTS TERATOGENIC?

1971 • 37 citations

Placental transfer and neonatal elimination of diphenylhydantoin

1971 • 36 citations

POSSIBLE TERATOGENIC EFFECT OF TOLBUTAMIDE IN PREGNANCY

1961 • 34 citations

Imipramine and pregnancy.

1972 • 33 citations

DEXAMPHETAMINE SULPHATE AND HUMAN MALFORMATIONS

1967 • 33 citations

Meclozine and Fetal Malformations: a Prospective Study

1964 • 31 citations

THE PRODUCTION OF FŒTAL ABNORMALITIES IN RABBITS BY IMIPRAMINE

1963 • 29 citations

Masculinization of the female fetus associated with norethindrone-mestranol therapy during pregnancy

1967 • 29 citations

ON THE EFFECT EXERTED BY FIRST-LINE TUBERCULOSIS MEDICINES ON THE FOETUS.

1964 • 25 citations

Book Review: Chemistry and Prevention of Congenital Anomalies

1964 • 24 citations

Ethionamide treatment and pregnancy.

1966 • 24 citations

Malformed infant.

1972 • 20 citations

Chlorpropamide and Foetal Damage

1963 • 18 citations

CONGENITAL EFFECTS OF BROMISM?

1972 • 18 citations

USE OF ANTIDEPRESSANT DRUGS DURING THE FIRST TRIMESTER

1969 • 17 citations

FETAL AND NEONATAL HAZARDS FROM DRUGS ADMINISTERED DURING PREGNANCY.

1964 • 16 citations

ANTICONVULSANT DRUGS AND CONGENITAL ABNORMALITIES

1969 • 15 citations

Antibiotics in Early Pregnancy and Congenital Malformations

1965 • 15 citations

POSSIBLE TERATOGENIC EFFECT OF TOLBUTAMIDE IN THE PREGNANT PREDIABETIC

1961 • 14 citations

ANTIDIABETIC DRUGS AND TERATOGENICITY

1963 • 14 citations

Chemistry and Prevention of Congenital Anomalies

1964 • 14 citations

Quinine and congenital injuries of ear and eye of the foetus.

1948 • 14 citations

Teratogenic effects of anticonvulsants.

1971 • 13 citations

Increased Incidence of Malformations—Chance or Change?

1964 • 12 citations

Phenmetrazine and Foetal Abnormalities

1962 • 11 citations

Drugs and Congenital Anomalies.

1962 • 10 citations

Fetal Pharmacology

1972 • 10 citations

Chromosome studies in pregnant rhesus macaque given LSD-25.

1970 • 9 citations

Tolbutamide in pregnancy and diabetes.

1969 • 9 citations

Hormone therapy during pregnancy: effects on the fetus and newborn.

1958 • 7 citations

Metabolic influences of pregnancy and acidosis on bone electrolytes

1962 • 7 citations

Multiple Severe Malformations in a Child of a Diabetic Mother Treated with Insulin and Dibein1 During Pregnancy

1970 • 6 citations

[Malformations caused by follicular hormones in humans].

1959 • 4 citations

[Carbutamide and malformations in children].

1970 • 3 citations

An Address ON THE OPSONIC THEORY AND ITS PRACTICAL APPLICATION TO MEDICINE AND SURGERY: Given before the University of Birmingham Medical Society, January 26th, 1906

1906 • 1 citations

Remarks on Cases of Multiple Synovitis, following Injuries to Joints

1883 • 1 citations

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