The use of autoradiographic techniques for the identification and mapping of transmitter-specific neurones in the brain

The Cerebellum as a Neuronal Machine

1967 • 3,202 citations

The autoradiographic demonstration of axonal connections in the central nervous system

1972 • 1,596 citations

Evidence for the existence of monoamine neurons in the central nervous system

1965 • 1,538 citations

Handbook of Neurochemistry

1972 • 1,374 citations

Cellular localization of brain monoamines.

1962 • 1,141 citations

Characteristics of Excitatory and Inhibitory Synapses in the Central Nervous System of the Cat

1965 • 914 citations

Role of Transmitter Uptake Mechanisms in Synaptic Neurotransmission

1971 • 768 citations

The Uptake and Storage of Noradrenaline in Sympathetic Nerves

1967 • 706 citations

The uptake and storage of Noradrenaline in Sympathetic Nerves

1967 • 680 citations

EFFECTS OF 6‐HYDROXYDOPAMINE ON CATECHOLAMINE CONTAINING NEURONES IN THE RAT BRAIN

1970 • 653 citations

6-Hydroxydopamine and catecholamine neurons

1971 • 637 citations

THE UPTAKE OF [³H]GABA BY SLICES OF RAT CEREBRAL CORTEX

1968 • 543 citations

Kinetics of serotonin accumulation into slices from rat brain: relationship to catecholamine uptake.

1970 • 518 citations

In vitro studies on central and peripheral monoamine neurons at the ultrastructural level

1968 • 499 citations

On the projections from the locus coeruleus noradrenaline neurons: The cerebellar innervation

1971 • 477 citations

High affinity uptake systems for glycine, glutamic and aspartic acids in synaptosomes of rat central nervous tissues

1972 • 476 citations

Glial Cell Function: Uptake of Transmitter Substances

1971 • 460 citations

Catecholamine uptake by synaptosomes in homogenates of rat brain: stereospecificity in different areas.

1969 • 445 citations

Localizing Tritiated Norepinephrine in Sympathetic Axons by Electron Microscopic Autoradiography

1962 • 443 citations

GABA UPTAKE IN RAT CENTRAL NERVOUS SYSTEM: COMPARISON OF UPTAKE IN SLICES AND HOMOGENATES AND THE EFFECTS OF SOME INHIBITORS

1971 • 417 citations

The Distribution of Adrenergic Nerve Fibres to the Blood Vessels in Skeletal Muscle

1965 • 412 citations

Blockage of caudate-evoked inhibition of neurons in the substantia nigra by picrotoxin

1971 • 387 citations

AUTORADIOGRAPHY WITH THE ELECTRON MICROSCOPE

1964 • 375 citations

Studies of the uptake of3H-GABA and [3H]glycine in slices and homogenates of rat brain and spinal cord by electron microscopic autoradiography

1972 • 371 citations

The distribution of cholinesterase in cholinergic neurons demonstrated with the electron microscope

1966 • 351 citations

Pharmacological properties of the postsynaptic inhibition by Purkinje cell axons and the action of ?-aminobutyric acid on Deiters neurones

1967 • 346 citations

Monosynaptic inhibition of neurons of the substantia nigra by caudatonigral fibers

1971 • 344 citations

Localizing 3H-GABA in Nerve Terminals of Rat Cerebral Cortex by Electron Microscopic Autoradiography

1971 • 303 citations

The origin of cerebellar-induced inhibition of Deiters neurones I. Monosynaptic initiation of the inhibitory postsynaptic potentials

1966 • 300 citations

AN ARTEFACT IN RADIOAUTOGRAPHY DUE TO BINDING OF FREE AMINO ACIDS TO TISSUES BY FIXATIVES

1967 • 300 citations

Unique High Affinity Uptake Systems for Glycine, Glutamic and Aspartic Acids in Central Nervous Tissue of the Rat

1971 • 295 citations

Glutamate decarboxylase in inhibitory neurons

1970 • 294 citations

Studies on the GABA pathway—I

1961 • 287 citations

On the source of gaba-containing terminals in the substantia nigra. Electron microscopic autoradiographic and biochemical studies

1973 • 286 citations

Autoradiography of some suspected neurotransmitter substances: GABA glycine, glutamic acid, histamine, dopamine, and pl-dopa

1971 • 275 citations

Glutamate and γ-Aminobutyric Acid in Brain

1970 • 269 citations

Perspectives in Neuropharmacology

1973 • 261 citations

GLYCINE UPTAKE IN RAT CENTRAL NERVOUS SYSTEM SLICES AND HOMOGENATES: EVIDENCE FOR DIFFERENT UPTAKE SYSTEMS IN SPINAL CORD AND CEREBRAL CORTEX

1971 • 256 citations

The distribution of glutamate decarboxylase and aspartate transaminase in subcellular fractions of rat and guinea-pig brain

1968 • 249 citations

The characterisation of [3H]GABA uptake into the satellite glial cells of rat sensory ganglia

1974 • 246 citations

Further mapping out of central noradrenaline neuron systems: Projections of the ‘subcoeruleus’ area

1972 • 245 citations

The effect of potassium on neuronal differentiation in cultures of dissociated newborn rat cerebellum

1972 • 244 citations

Autoradiographic identification of cerebral and cerebellar cortical neurons accumulating labeled gamma-aminobutyric acid (3H-GABA)

1972 • 244 citations

Glutamic acid as a synaptic transmitter in the nervous system. A review

1972 • 243 citations

Amino Acid Transmitters

1970 • 235 citations

Projections ascendantes du locus coeruleus et d'autres neurones aminergiques pontiques au niveau du prosencéphale du rat

1972 • 232 citations

Pharmacological Properties of Excitatory Neuromuscular Synapses in the Locust

1968 • 225 citations

Neurotransmitter uptake: A tool in identifying neurotransmitter-specific pathways

1973 • 219 citations

Cholinergic Receptor Molecules and Cholinesterase Molecules at Mouse Skeletal Muscle Junctions

1971 • 212 citations

RELEASE OF γ‐AMINOBUTYRIC ACID INTO THE FOURTH VENTRICLE INDUCED BY STIMULATION OF THE CAT'S CEREBELLUM

1969 • 207 citations

Synapses on the purkinje cell spines in the mouse an electronmicroscopic study

1967 • 198 citations

A histochemical study of cholinergic fibres in the cerebral cortex.

1965 • 198 citations

Acetylcholine Receptors: Number and Distribution at Neuromuscular Junctions in Rat Diaphragm

1972 • 194 citations

The effect of bicuculline upon synaptic inhibition in the cerebral and cerebellar cortices of the cat

1971 • 193 citations

Effects of serotonin on central neurons: microiontophoretic administration.

1972 • 190 citations

MEASUREMENT OF γ‐AMINOBUTYRIC ACID IN ISOLATED NERVE CELLS OF CAT CENTRAL NERVOUS SYSTEM

1971 • 189 citations

Characterization and tissue localization of catecholamine synthesizing enzymes.

1972 • 186 citations

AN ELECTRON MICROSCOPIC CHARACTERIZATION OF CLASSES OF SYNAPTIC VESICLES BY MEANS OF CONTROLLED ALDEHYDE FIXATION

1970 • 186 citations

Localization of tritiated serotonin in rat brain by electron-microscopic autoradiography.

1967 • 179 citations

Autoradiographic Localization of 3H-GABA in Rat Retina

1972 • 170 citations

SUBCELLULAR DISTRIBUTION OF ENDOGENOUS AND [³H] γ‐AMINOBUTYRIC ACID IN RAT CEREBRAL CORTEX

1969 • 154 citations

The Uptake of [γ- ³ H] Aminobutyric Acid in the Goldfish Retina

1971 • 152 citations

New Concepts in Neurotransmitter Regulation

1974 • 148 citations

Noradrenergic axon terminals in the cerebral cortex of rat. II. Quantitative data revealed by light and electron microscope radioautography of the frontal cortex

1973 • 147 citations

Recent Developments on the Ultrastructural Aspect of Adrenergic Nerve Endings in Various Experimental Conditions

1969 • 146 citations

Cellular localization of labeled gamma-aminobutyric acid (3H_GABA) in rat cerebellar cortex: an autoradiographic study

1970 • 145 citations

LOCALIZATION OF THE SITES OF γ-AMINOBUTYRIC ACID (GABA) UPTAKE IN LOBSTER NERVE-MUSCLE PREPARATIONS

1971 • 139 citations

Effects of globus pallidus lesions and Parkinson's disease on brain glutamic acid decarboxylase

1971 • 139 citations

Immunohistochemical localization of aromatic L-amino acid decarboxylase (DOPA decarboxylase) in central dopamine and 5-hydroxytryptamine nerve cell bodies of the rat

1973 • 139 citations

GLUTAMATE UPTAKE BY A STIMULATED INSECT NERVE MUSCLE PREPARATION

1970 • 136 citations

Light and electron microscopic autoradiography on spinal cord slices after incubation with labeled glycine

1971 • 127 citations

Immunohistochemical studies on monoamine-containing cell systems

1973 • 125 citations

New Concepts in Neurotransmitter Regulation

1973 • 123 citations

INTRANEURAL DISTRIBUTION OF EXOGENOUS NOREPINEPHRINE IN THE CENTRAL NERVOUS SYSTEM OF THE RAT

1970 • 122 citations

Electron-Microscopic Autoradiography of Rat Hypothalamus after Intraventricular H ³ -Norepinephrine

1966 • 121 citations

Selective accumulation of [3H]GABA by stellate cells in rat cerebellar cortexin vivo

1972 • 117 citations

Cellular location of the uptake of some amino acids into the rabbit retina

1972 • 116 citations

THE HISTOCHEMICAL DEMONSTRATION OF γ‐AMINOBUTYRIC ACID METABOLISM BY REDUCTION OF A TETRAZOLIUM SALT*

1965 • 116 citations

CNS at the Cellular Level: Identity of Transmitter Agents

1970 • 113 citations

The uptake of [¹⁴C]glycine by slices of mammalian spinal cord

1971 • 112 citations

A carrier-mediated transfer model for the accumulation of 14C γ-aminobutyric acid by subcellular brain particles

1965 • 110 citations

Autoradiographic uptake patterns of [3H]GABA and [3H]-glycine in central nervous tissues with special reference to the cat spinal cord

1973 • 110 citations

QUANTITATIVE HISTOCHEMISTRY OF GLUTAMATE DECARBOXYLASE IN THE RAT HIPPOCAMPAL REGION

1971 • 109 citations

L-Glutamate at Insect Excitatory Nerve–Muscle Synapses

1968 • 103 citations

Cellular Localization of Dopamine-β-hydroxylase and Phenylethanolamine-N-methyl Transferase as Revealed by Immunohistochemistry

1971 • 101 citations

Autoradiographic localisation of tritiated glycine at ‘flat-vesicle’ synapses in spinal cord

1971 • 101 citations

THE BIOSYNTHESIS AND CONTENT OF GAMMA-AMINOBUTYRIC ACID IN THE GOLDFISH RETINA

1972 • 96 citations

Synaptosomes: Different Populations storing Catecholamines and Gamma-aminobutyric Acid in Homogenates of Rat Brain

1968 • 94 citations

Uptake of 14C Glycine by Spinal Cord

1969 • 90 citations

The uptake of ³H‐γ‐aminobutyric acid by the retina

1973 • 86 citations

Electron-microscopic localization of tritiated norepinephrine in rat brain: effect of drugs.

1967 • 86 citations

ULTRASTRUCTURAL IDENTIFICATION OF CATECHOLAMINE-CONTAINING CENTRAL SYNAPTIC TERMINALS

1973 • 83 citations

Autoradiographic identification of rabbit retinal neurons that take up GABA

1970 • 82 citations

Is Polyoxymethylene a Cosmopolymer?

1972 • 81 citations

Kinetic analysis of amino acid uptake by the rat retina in vitro.

1973 • 80 citations

Localization of [3H]GABA in tissue culture of rat cerebellum using electron microscopy radioautography

1972 • 76 citations

Photodetachment of Electrons from Major Negative Ions in the Lower D Region

1972 • 71 citations

Dopamine: a retinal neurotransmitter. II. Autoradiographic localization of H3-dopamine in the retina.

1971 • 70 citations

Accurate freehand injection into the lateral brain ventricle of the conscious mouse.

1968 • 68 citations

Uptake of [3H]noradrenaline and γ-[3H]Aminobutyric Acid in Isolated Tissues of Rat: An Autoradiographic and Fluorescence Microscopic Study

1971 • 67 citations

Uptake of the putative neurotransmitter, glycine, into the rabbit retina.

1972 • 65 citations

THE DISTRIBUTION OF LABELED NOREPINEPHRINE WITHIN SYMPATHETIC NERVE TERMINALS STUDIED WITH ELECTRON MICROSCOPE RADIOAUTOGRAPHY

1969 • 65 citations

Studies on uptake of intraventricularly administered tritiated noradrenaline and 5-hydroxytryptamine with combined fluorescence histochemical and autoradiographic techniques

1968 • 64 citations

EFFECTS OF AMINO‐OXYACETIC ACID ON [³H]GABA UPTAKE BY RAT BRAIN SLICES

1973 • 64 citations

Effect of inhibitors of γ‐aminobutyrate aminotransferase on the accumulation of H‐γ‐aminobutyric acid by the retina

1973 • 60 citations

Reduction in GAD I activity from the dorsal lateral region of the deafferented rat spinal cord

1973 • 58 citations

A COMPARISON OF γ‐AMINOBUTYRIC ACID METABOLISM IN RABBIT AND MOUSE NERVOUS TISSUE*

1965 • 58 citations

Localization of uptake of tritiated norepinephrine by rat brainin vivo andin vitro using electron microscopic autoradiography

1967 • 58 citations

Morphological and Cytochemical Studies on the Synapses in the Autonomic Nervous System

1969 • 57 citations

CATECHOLAMINE AND ACETYLCHOLINESTERASE DISTRIBUTION IN RELATION TO NORADRENALINE RELEASE. AN ENZYME HISTOCHEMICAL AND AUTORADIOGRAPHIC STUDY ON THE INNERVATION OF THE CAT NICTITATING MUSCLE

1968 • 55 citations

Neuronal uptake processes for amines and amino acids.

1970 • 54 citations

A Possible Enzyme Barrier for γ-Aminobutyric Acid in the Central Nervous System

1968 • 52 citations

Distribution and localization of sites of gamma aminobutyric acid metabolism in the adult rat brain.

1973 • 51 citations

AN EXAMINATION OF ADRENERGIC AXONS AROUND PANCREATIC ARTERIOLES OF THE CAT FOR THE PRESENCE OF ACETYLCHOLINESTERASE BY HIGH RESOLUTION AUTORADIOGRAPHIC AND HISTOCHEMICAL METHODS

1968 • 49 citations

Effect of amino-oxyacetic acid on the accumulation of 3H- -aminobutyric acid (3H-GABA) by rat retina.

1973 • 49 citations

Autoradiographic demonstration of uptake and accumulation of3H-6-hydroxydopamine in adrenergic nerves

1971 • 47 citations

The Role of Sheath Cells in Glutamate Uptake by Insect Nerve Muscle Preparations

1971 • 45 citations

An autoradiographic study of uptake of exogenous glycine by vertebrate spinal cord splicesin vitro

1972 • 45 citations

Localization of triated dopamine in the median eminence of the rat hypothalamus by electron microscope autoradiography

1973 • 44 citations

Selective Accumulation of 3H-Serotonin by Nerve Terminals of Raphe Neurones: An Autoradiographic Study

1973 • 42 citations

[3H]GABA uptake in growing cerebellar tissue: Autoradiography of intraocular transplants

1973 • 40 citations

Role of amino acids and peptides in synaptic transmission

1973 • 40 citations

LOCALIZATION OF TRITIATED NOREPINEPHRINE IN VASCULAR SYMPATHETIC AXONS OF THE RAT INTESTINE AND MESENTERY BY ELECTRON MICROSCOPE RADIOAUTOGRAPHY

1968 • 40 citations

HISTOCHEMICAL LOCALIZATION OF BRAIN SUCCINIC SEMIALDEHYDE DEHYDROGENASE-A γ-AMINOBUTYRIC ACID DEGRADATIVE ENZYME

1971 • 37 citations

IMMUNOCHEMICAL STUDIES ON GLUTAMIC ACID DECARBOXYLASE (EC 4.1.1.15) FROM MOUSE BRAIN¹

1973 • 37 citations

Ultrastructural Localization of Choline Acetyltransferase and Acetylcholinesterase in Central and Peripheral Nervous Tissue

1971 • 37 citations

The cerebellum as a neuronal machine

1969 • 35 citations

Autoradiographic investigation of the distribution of [14C]GABA in tissues of normal and aminooxyacetic acid-treated mice

1969 • 34 citations

Separation of catecholamine-storing synaptosomes in different regions of rat brain.

1969 • 32 citations

Properties of a Possible Superfluid State of 3He

1973 • 24 citations

Uptake of [14C]glutamate into dorsal and ventral roots of spinal nerves of the rat

1973 • 18 citations

Studies of neurotransmitters at the synaptic level

1972 • 17 citations

Studies of Neurotransmitters at the Synaptic Level.

1973 • 14 citations

Tissue binding of tritiated norepinephrine in pigmented nuclei of human brain

1968 • 12 citations

Uptake of tritiated glycine into neurons of the human retina

1972 • 11 citations

Distribution of 14C-Thiosemicarbazide in the Rat Brain: an Attempt to localize Sites of γ-Aminobutyric Acid Production

1970 • 9 citations

Distribution of a catecholamine-binding mechanism in rat brain

1967 • 8 citations

Uptake of [14C]-glycine by rat spinal cord.

1969 • 5 citations