GTPase-activating protein interactions with the viral and cellular Src kinases.

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

ras GENES

1987 • 3,818 citations

A Cytoplasmic Protein Stimulates Normal N- ras p21 GTPase, But Does Not Affect Oncogenic Mutants

1987 • 1,197 citations

Requirement for ras proto-oncogene function during serum-stimulated growth of NIH 3T3 cells

1985 • 913 citations

Phosphorylation of GAP and GAP-associated proteins by transforming and mitogenic tyrosine kinases

1990 • 767 citations

Requirement for c-ras proteins during viral oncogene transformation

1986 • 680 citations

Cloning of bovine GAP and its interaction with oncogenic ras p21

1988 • 666 citations

Association between the PDGF receptor and members of the src family of tyrosine kinases

1990 • 650 citations

ras GTPase activating protein: Signal transmitter and signal terminator

1989 • 621 citations

PDGF β-receptor stimulates tyrosine phosphorylation of GAP and association of GAP with a signaling complex

1990 • 561 citations

Guanosine Triphosphatase Activating Protein (GAP) Interacts with the p21 ras Effector Binding Domain

1988 • 533 citations

Isolation of monoclonal antibodies that recognize the transforming proteins of avian sarcoma viruses

1983 • 518 citations

Molecular Cloning of Two Types of GAP Complementary DNA from Human Placenta

1988 • 492 citations

PDGF induction of tyrosine phosphorylation of GTPase activating protein

1989 • 478 citations

Signal transduction from membrane to cytoplasm: growth factors and membrane-bound oncogene products increase Raf-1 phosphorylation and associated protein kinase activity.

1988 • 458 citations

Binding of Transforming Protein, P47 ^gag-crk , to a Broad Range of Phosphotyrosine-containing Proteins

1990 • 433 citations

Cell Transformation by the Viral src Oncogene

1987 • 405 citations

The cytoplasmic protein GAP is implicated as the target for regulation by the ras gene product

1988 • 402 citations

Binding of GAP to Activated PDGF Receptors

1990 • 396 citations

Adp-Ribosylating Toxins and G Proteins: Insights into Signal Transduction

1990 • 285 citations

Non-catalytic domains of cytoplasmic protein-tyrosine kinases: regulatory elements in signal transduction.

1988 • 250 citations

Genetics of src: Structure and Functional Organization of a Protein Tyrosine Kinase

1989 • 197 citations

Phosphatidylinositol kinase activity associates with viral p60src protein.

1989 • 194 citations

ras and GAP—Who's controlling whom?

1990 • 185 citations

Stable Association of Activated pp60^src with Two Tyrosine-Phosphorylated Cellular Proteins

1989 • 168 citations

Regulation of Cell Growth and Transformation by Tyrosine-Specific Protein Kinases: The Search for Important Cellular Substrate Proteins

1983 • 164 citations

A C-terminal domain of GAP is sufficient to stimulate ras p21 GTPase activity.

1989 • 161 citations

Activation of the transforming potential of p60c-src by a single amino acid change.

1986 • 161 citations

Purification of the catalytically active phosphorylated form of insulin receptor kinase by affinity chromatography with O-phosphotyrosyl-binding antibodies

1985 • 124 citations

Oncogenes and Growth Control

1986 • 71 citations

Transformation of rat cells by fusion-infection with Rous sarcoma virus

1980 • 52 citations

Phosphatidylinositol Kinase Activity Associates with Viral p60^src Protein

1989 • 46 citations

Localization of conserved and nonconserved epitopes within the Rous sarcoma virus-encoded src protein

1986 • 34 citations

In vivo phosphorylation states and kinase activities of transforming p60c-src mutants.

1989 • 21 citations