Thyroid hormone modulates apolipoprotein B gene expression in HepG2 cells

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

The apolipoprotein B gene is constitutively expressed in HepG2 cells: regulation of secretion by oleic acid, albumin, and insulin, and measurement of the mRNA half-life.

1989 • 414 citations

Integrated regulation of very low density lipoprotein triglyceride and apolipoprotein-B kinetics in man: Normolipemic subjects, familial hypertriglyceridemia and familial combined hyperlipidemia

1981 • 301 citations

Growth hormone gene transcription is regulated by thyroid and glucocorticoid hormones in cultured rat pituitary tumor cells.

1982 • 280 citations

Insulin modulation of hepatic synthesis and secretion of apolipoprotein B by rat hepatocytes.

1990 • 251 citations

Kinetic bases of the primar hperlipidaemias: studies of apolipoprotein B turnover in geneticall defined subjects

1980 • 251 citations

Influence of mevinolin on metabolism of low density lipoproteins in primary moderate hypercholesterolemia.

1985 • 210 citations

Lovastatin therapy reduces low density lipoprotein apoB levels in subjects with combined hyperlipidemia by reducing the production of apoB-containing lipoproteins: implications for the pathophysiology of apoB production.

1990 • 210 citations

Apolipoprotein B is both integrated into and translocated across the endoplasmic reticulum membrane. Evidence for two functionally distinct pools.

1990 • 192 citations

Thyroid hormone modulates the introduction of a stop codon in rat liver apolipoprotein B messenger RNA.

1988 • 191 citations

Degradation of newly synthesized apolipoprotein B-100 in a pre-Golgi compartment.

1990 • 182 citations

Effects of oleate and insulin on the production rates and cellular mRNA concentrations of apolipoproteins in HepG2 cells.

1989 • 150 citations

Regulation of the production and catabolism of plasma low density lipoproteins in hypertriglyceridemic subjects. Effect of weight loss.

1985 • 125 citations

Apolipoprotein B messenger RNA editing in the rat liver. Modulation by fasting and refeeding a high carbohydrate diet.

1990 • 114 citations

Apolipoprotein gene expression in the rat is regulated in a tissue-specific manner by thyroid hormone

1988 • 110 citations

Transcriptional and posttranscriptional regulation of rat hepatic 3-hydroxy-3-methylglutaryl-coenzyme A reductase by thyroid hormones.

1988 • 74 citations

Synthesis of Carbamyl Phosphate Synthetase in Amphibian Liver in Vitro

1969 • 49 citations

Secretion of apolipoprotein B in serum‐free cultures of human hepatoma cell line, HepG2

1990 • 46 citations

Induction of brain tubulin by triidothyronine: dual effect of the hormone on the synthesis and turnover of the protein

1985 • 30 citations

A simple method for the preparation of extracts from animal cells which catalyze efficient in vitro protein synthesis.

1983 • 29 citations