Functional conservation between Schizosaccharomyces pombe ste8 and Saccharomyces cerevisiae STE11 protein kinases in yeast signal transduction

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

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1984 • 4,231 citations

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1991 • 3,691 citations

Dideoxy sequencing method using denatured plasmid templates

1986 • 1,537 citations

The molecular biology of the yeast saccharomyces: Life cycle and inheritance

1982 • 1,361 citations

Laboratory course manual for methods in yeast genetics

1986 • 1,310 citations

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1991 • 1,225 citations

nmt1 of fission yeast. A highly transcribed gene completely repressed by thiamine.

1990 • 859 citations

The STE4 and STE18 genes of yeast encode potential β and γ subunits of the mating factor receptor-coupled G protein

1989 • 491 citations

Genetic engineering of Schizosaccharomyces pombe: A system for gene disruption and replacement using the ura4 gene as a selectable marker

1988 • 467 citations

Two genes required for cell fusion during yeast conjugation: evidence for a pheromone-induced surface protein.

1987 • 439 citations

The yeast SCG1 gene: A Gα-like protein implicated in the a- and α-factor response pathway

1987 • 431 citations

Four mating-type genes control sexual differentiation in the fission yeast.

1988 • 388 citations

Fission yeast genes that confer resistance to staurosporine encode an AP-1-like transcription factor and a protein kinase related to the mammalian ERK1/MAP2 and budding yeast FUS3 and KSS1 kinases.

1991 • 369 citations

Mutants of Saccharomyces cerevisiae unresponsive to cell division control by polypeptide mating hormone.

1980 • 368 citations

GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction

1987 • 365 citations

Schizosaccharomyces pombe ste11+ encodes a transcription factor with an HMG motif that is a critical regulator of sexual development.

1991 • 352 citations

Nucleotide sequences of STE2 and STE3 , cell type-specific sterile genes from Saccharomyces cerevisiae

1985 • 351 citations

The yeast α-factor receptor: structural properties deduced from the sequence of theSTE2gene

1985 • 318 citations

Evidence the yeast STE3 gene encodes a receptor for the peptide pheromone a factor: gene sequence and implications for the structure of the presumed receptor.

1986 • 305 citations

A putative protein kinase overcomes pheromone-induced arrest of cell cycling in S. cerevisiae

1989 • 298 citations

The product of the mei3+ gene, expressed under control of the mating-type locus, induces meiosis and sporulation in fission yeast.

1987 • 257 citations

Identification and regulation of a gene required for cell fusion during mating of the yeast Saccharomyces cerevisiae.

1987 • 253 citations

RAN1 + controls the transition from mitotic division to meiosis in fission yeast

1985 • 228 citations

Signal Transduction During Pheromone Response in Yeast

1991 • 225 citations

FUS3 represses CLN1 and CLN2 and in concert with KSS1 promotes signal transduction.

1991 • 211 citations

byr2, a Schizosaccharomyces pombe gene encoding a protein kinase capable of partial suppression of the ras1 mutant phenotype.

1991 • 208 citations

Two Genes Required for Cell Fusion During Yeast Conjugation: Evidence for a Pheromone-Induced Surface Protein

1987 • 205 citations

Nucleotide sequence of the yeast regulatory gene STE7 predicts a protein homologous to protein kinases.

1986 • 189 citations

Mutants of Schizosaccharomyces pombe which sporulate in the haploid state

1985 • 184 citations

STE11 is a protein kinase required for cell-type-specific transcription and signal transduction in yeast.

1990 • 178 citations

Occurrence in Saccharomyces cerevisiae of a gene homologous to the cDNA coding for the alpha subunit of mammalian G proteins.

1987 • 170 citations

Isolation and characterization of a gene encoding a G-protein alpha subunit from Schizosaccharomyces pombe: involvement in mating and sporulation pathways.

1991 • 156 citations

A gene which encodes a predicted protein kinase can restore some functions of the ras gene in fission yeast.

1988 • 153 citations

Mutants of the fission yeast Schizosaccharomyces pombe which alter the shift between cell proliferation and sporulation

1985 • 149 citations

Pheromone-dependent phosphorylation of the yeast STE12 protein correlates with transcriptional activation.

1991 • 148 citations

Mating pheromones of the fission yeast Schizosaccharomyces pombe: purification and structural characterization of M-factor and isolation and analysis of two genes encoding the pheromone.

1992 • 145 citations

The Schizosaccharomyces pombe mam2 gene encodes a putative pheromone receptor which has a significant homology with the Saccharomyces cerevisiae Ste2 protein.

1991 • 138 citations

Yeast peptide pheromones, a-factor and α-factor, activate a common response mechanism in their target cells

1986 • 137 citations

Overproduction of the yeast STE12 protein leads to constitutive transcriptional induction.

1990 • 133 citations

A specific inhibitor of the ran1+ protein kinase regulates entry into meiosis in Schizosaccharomyces pombe

1988 • 130 citations

Mutations in a gene encoding the alpha subunit of a Saccharomyces cerevisiae G protein indicate a role in mating pheromone signaling.

1988 • 121 citations

Commitment to meiosis in fission yeast

1973 • 116 citations

Physiological aspects of conjugation in fission yeast

1971 • 114 citations

Initiation of meiotic recombination by double-strand DNA breaks in S. pombe

1986 • 108 citations

Role of STE genes in the mating factor signaling pathway mediated by GPA1 in Saccharomyces cerevisiae.

1988 • 107 citations

Mating pheromone-like diffusible factor released by Schizosaccharomyces pombe

1986 • 92 citations

Yeast STE7, STE11, and STE12 genes are required for expression of cell-type-specific genes.

1988 • 92 citations

The ras1 function of Schizosaccharomyces pombe mediates pheromone-induced transcription.

1992 • 92 citations

Identification and Regulation of a Gene Required for Cell Fusion during Mating of the Yeast Saccharomyces cerevisiae

1987 • 90 citations

Common signal transduction system shared by STE2 and STE3 in haploid cells of Saccharomyces cerevisiae : autocrine cell-cycle arrest results from forced expression of STE2

1987 • 80 citations

Schizosaccharomyces pombe ras1 and byr1 are functionally related genes of the ste family that affect starvation-induced transcription of mating-type genes.

1990 • 79 citations

Sex appeal in fission yeast

1987 • 75 citations

Signal transduction in yeast mating: Receptors, transcription factors, and the kinase connection

1991 • 71 citations

Signal transduction in yeast mating: Receptors, transcription factors, and the kinase connection

1991 • 66 citations

Molecular cloning and characterization of the STE7 and STE11 genes of Saccharomyces cerevisiae.

1985 • 65 citations

The pat1 protein kinase controls transcription of the mating-type genes in fission yeast.

1990 • 59 citations

byr2, a Schizosaccharomyces pombe Gene Encoding a Protein Kinase Capable of Partial Suppression of the ras1 Mutant Phenotype

1991 • 56 citations

New vectors in fission yeast: application for cloning the his2 gene

1991 • 55 citations

Genetical Analysis of a Sterile Mutant by Protoplast Fusion in the Fission Yeast Schizosaccharomyces pombe

1980 • 48 citations

Sterile mutants of Schizosaccharomyces pombe: Analysis by somatic hybridization

1982 • 40 citations

Pheromone-induced meiosis in P-specific mutants of fission yeast

1989 • 38 citations

Novel sterile mutants of the fission yeast Schizosaccharomyces pombe which are defective in their response to starvation

1990 • 34 citations

Pheromone production and response in sterile mutants of fission yeast

1991 • 32 citations

Yeast STE7, STE11, and STE12 Genes Are Required for Expression of Cell-Type-Specific Genes

1988 • 30 citations

Sterility (ste) genes of Schizosaccharomyces pombe

1987 • 29 citations

Mutations in a Gene Encoding the α Subunit of a Saccharomyces cerevisiae G Protein Indicate a Role in Mating Pheromone Signaling

1988 • 29 citations

Molecular Cloning and Characterization of the STE7 and STE11 Genes of Saccharomyces cerevisiae

1985 • 18 citations

Sterile UGA nonsense mutants of fission yeast

1991 • 14 citations