Involvement of O₂radicals in ‘autoimmune’ diabetes

Type I Diabetes Mellitus

1986 • 1,615 citations

Increased superoxide anion release from human endothelial cells in response to cytokines.

1986 • 365 citations

Human tumor necrosis factor potentiates human interleukin 1-mediated rat pancreatic beta-cell cytotoxicity.

1987 • 305 citations

Protection by superoxide dismutase, catalase, and poly(ADP-ribose) synthetase inhibitors against alloxan- and streptozotocin-induced islet DNA strand breaks and against the inhibition of proinsulin synthesis.

1982 • 251 citations

UCLA Symposia on Molecular and Cellular Biology

1983 • 203 citations

Alloxan toxicity to the pancreatic B-cell

1982 • 162 citations

Prevention of diabetes in BioBreeding/Worcester rats with monoclonal antibodies that recognize T lymphocytes or natural killer cells.

1986 • 156 citations

Regulation of proinsulin synthesis in pancreatic islets and a new aspect to insulin-dependent diabetes

1981 • 147 citations

Combined Treatment With Nicotinamide and Desferrioxamine Prevents Islet Allograft Destruction in NOD Mice

1986 • 110 citations

Immune attack on pancreatic islet transplants in the spontaneously diabetic BioBreeding/Worcester (BB/W) rat is not MHC restricted.

1985 • 59 citations

Islet Allografts Are Destroyed by Disease Occurrence in the Spontaneously Diabetic BB Rat

1986 • 56 citations

CHRONIC CYCLOSPORINE NEPHROTOXICITY A RODENT MODEL

1988 • 54 citations

EFFECT OF CYCLOSPORINE ON IMMUNOLOGICALLY MEDIATED DIABETES IN NONOBESE DIABETIC MICE1

1988 • 40 citations

Transplantation of cultured pancreatic islets to BB rats.

1986 • 40 citations

Islet allografts are destroyed by disease occurrence in the spontaneously diabetic BB rat

1986 • 26 citations

Effect of extracellularly generated free radicals on the plasma membrane permeability of isolated pancreatic B-cells

1986 • 23 citations