Human hepatic low-density lipoprotein receptors: associations of receptor activities in vitro with plasma lipid and apolipoprotein concentrations in vivo

Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge

1972 • 31,801 citations

Binding and Degradation of Low Density Lipoproteins by Cultured Human Fibroblasts

1974 • 1,481 citations

The Metabolic Basis of Inherited Disease.

1972 • 1,407 citations

A comprehensive evaluation of the heparin–manganese precipitation procedure for estimating high density lipoprotein cholesterol

1978 • 1,300 citations

[16] Protein determination in membrane and lipoprotein samples: Manual and automated procedures

1981 • 765 citations

The metabolism of low density lipoprotein in familial type II hyperlipoproteinemia

1972 • 629 citations

Increased binding of low density lipoprotein to liver membranes from rats treated with 17 alpha-ethinyl estradiol.

1979 • 571 citations

Liver Transplantation to Provide Low-Density-Lipoprotein Receptors and Lower Plasma Cholesterol in a Child with Homozygous Familial Hypercholesterolemia

1984 • 442 citations

Two independent lipoprotein receptors on hepatic membranes of dog, swine, and man. Apo-B,E and apo-E receptors.

1981 • 378 citations

Cholestyramine Promotes Receptor-Mediated Low-Density-Lipoprotein Catabolism

1980 • 357 citations

Atherosclerosis: The low-density lipoprotein receptor hypothesis

1977 • 341 citations

On the metabolic conversion of human plasma very low density lipoprotein to low density lipoprotein

1973 • 339 citations

High-Density Lipoproteins and Atherosclerosis

1978 • 230 citations

COMMON DNA POLYMORPHISM WITHIN CODING SEQUENCE OF APOLIPOPROTEIN B GENE ASSOCIATED WITH ALTERED LIPID LEVELS

1986 • 217 citations

Cholesterol-lowering effect of mevinolin, an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme a reductase, in healthy volunteers.

1982 • 206 citations

Receptor-dependent and receptor-independent degradation of low density lipoprotein in normal rabbits and in receptor-deficient mutant rabbits.

1982 • 201 citations

The endocrine function of the human ovary

1977 • 201 citations

Immunoturbidimetric assays of apolipoproteins A, AI, AII, and B in serum.

1986 • 191 citations

Low Density Lipoprotein Receptors in Bovine Adrenal Cortex. II. Low Density Lipoprotein Binding to Membranes Prepared from Fresh Tissue*

1979 • 173 citations

FREQUENCY OF RISK FACTORS FOR ISCHÆMIC HEART-DISEASE IN A HEALTHY BRITISH POPULATION

1974 • 166 citations

The metabolism in vitro of human low-density lipoprotein by the human hepatoma cell line Hep G2

1983 • 130 citations

Radioiodination of human low density lipoprotein: A comparison of four methods

1976 • 128 citations

The epidemiology of gallstone disease in Rome, Italy. Part II. Factors associated with the disease

1988 • 126 citations

Kinetic mechanisms determining variability in low density lipoprotein levels and rise with age.

1985 • 124 citations

WHY DOES PLASMA LOW DENSITY LIPOPROTEIN CONCENTRATION IN ADULTS INCREASE WITH AGE?

1984 • 114 citations

A Guidebook to Lipoprotein Technique

1984 • 111 citations

Receptor-mediated catabolism of homologous low density lipoproteins in cultured pig hepatocytes.

1981 • 94 citations

Cultured human hepatocytes. Evidence for metabolism of low density lipoproteins by a pathway independent of the classical low density lipoprotein receptor.

1986 • 84 citations

EVOLUTION OF THE LDL RECEPTOR CONCEPT–FROM CULTURED CELLS TO INTACT ANIMALS *

1980 • 78 citations

Estrogens induce low-density lipoprotein receptor activity and decrease intracellular cholesterol in human hepatoma cell line Hep G2

1987 • 76 citations

Characterization of hepatic low density lipoprotein binding and cholesterol metabolism in normal and homozygous familial hypercholesterolemic subjects.

1984 • 65 citations

Effects of compactin, mevalonate and low-density lipoprotein on 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity and low-density-lipoprotein-receptor activity in the human hepatoma cell line Hep G2

1984 • 64 citations

Receptor-Mediated Uptake in the Liver

1986 • 59 citations

Receptor-independent catabolism of low density lipoprotein. Involvement of the reticuloendothelial system.

1982 • 50 citations

Detection and quantitation of low density lipoprotein (LDL) receptors in human liver by ligand blotting, immunoblotting, and radioimmunoassay. LDL receptor protein content is correlated with plasma LDL cholesterol concentration.

1986 • 50 citations

Regulation of plasma levels of low-density lipoprotein cholesterol: interpretation of data on low-density lipoprotein turnover in man.

1986 • 46 citations

Lipoprotein binding to cultured human hepatoma cells.

1987 • 40 citations

Renal water and sodium handling in compensated liver cirrhosis: mechanism of the impaired natriuresis after saline loading

1985 • 36 citations

LDL receptors in bovine tissues assayed as the heparin-sensitive binding of 125I-labeled LDL in homogenates: relation between liver LDL receptors and serum cholesterol in the fetus and post term

1985 • 35 citations

Activity and Regulation of Low Density Lipoprotein Receptors in a Human Hepatoblastoma Cell Line

1984 • 25 citations

Metabolism of low-density lipoproteins by cultured hepatocytes from normal and homozygous familial hypercholesterolemic subjects

1986 • 24 citations

Role of the liver for the receptor-mediated catabolism of low-density lipoprotein in the 17α-ethinylestradiol-treated rat

1987 • 23 citations

Regulation of low-density lipoprotein apolipoprotein B levels

1987 • 19 citations

Are plasma lipoprotein cholesteryl esters utilized for biliary cholesterol and bile acid production in man?

1985 • 12 citations

In vitro studies of lipid metabolism in human liver

1987 • 11 citations

Regulation of Low Density Lipoprotein Receptor Function in a Human Hepatoma Cell Line

1984 • 7 citations