Expression of human full-length and minidystrophin in transgenic mdx mice: implications for gene therapy of Duchenne muscular dystrophy

Manipulating the mouse embryo: A laboratory manual

1986 • 4,548 citations

X chromosome-linked muscular dystrophy (mdx) in the mouse.

1984 • 1,678 citations

Primary structure of dystrophin-associated glycoproteins linking dystrophin to the extracellular matrix

1992 • 1,381 citations

Deficiency of a glycoprotein component of the dystrophin complex in dystrophic muscle

1990 • 996 citations

The molecular basis for Duchenne versus Becker muscular dystrophy: correlation of severity with type of deletion.

1989 • 940 citations

The mdx mouse diaphragm reproduces the degenerative changes of Duchenne muscular dystrophy

1991 • 892 citations

Very mild muscular dystrophy associated with the deletion of 46% of dystrophin

1990 • 578 citations

Association of dystrophin-related protein with dystrophin-associated proteins in mdx mouse muscle

1992 • 489 citations

Human dystrophin expression in mdx mice after intramuscular injection of DNA constructs

1991 • 486 citations

Efficient adenovirus-mediated transfer of a human minidystrophin gene to skeletal muscle of mdx mice

1993 • 455 citations

Dystrophin-associated proteins are greatly reduced in skeletal muscle from mdx mice.

1991 • 424 citations

Dystrophin-related protein is localized to neuromuscular junctions of adult skeletal muscle

1991 • 368 citations

THE mdx MOUSE SKELETAL MUSCLE MYOPATHY: I. A HISTOLOGICAL, MORPHOMETRIC AND BIOCHEMICAL INVESTIGATION

1988 • 343 citations

Quantitative analysis of the human alpha-skeletal actin gene in transgenic mice.

1993 • 169 citations

Dystrophin in skeletal muscle I. Western blot analysis using a monoclonal antibody

1989 • 167 citations

Multiple regulatory elements contribute differentially to muscle creatine kinase enhancer activity in skeletal and cardiac muscle.

1993 • 143 citations

Disruption of the dystrophin-glycoprotein complex in the cardiomyopathic hamster

1993 • 127 citations

Direct retroviral-mediated transfer of a dystrophin minigene into mdx mouse muscle in vivo

1993 • 120 citations

Human dystrophin expression corrects the myopathic phenotype in transgenic mdx mice

1992 • 69 citations

Human dystrophin gene transfer: production and expression of a functional recombinant DNA-based gene

1991 • 44 citations