Central hypothermic effects of some analogues of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and 1-methyl-4-phenylpyridinium ion (MPP+)

Metabolism of the neurotoxic tertiary amine, MPTP, by brain monoamine oxidase

1984 • 1,092 citations

MPTP

1986 • 293 citations

MPTP: A neurotoxin producing a parkinsonian syndrome

1987 • 133 citations

The effects of selective dopamine receptor agonists and antagonists on body temperature in rats

1987 • 82 citations

Serotonergic mechanisms in the hypothalamus mediate thermoregulatory responses in rats

1983 • 63 citations

Neuropsychopharmacology of the Trace Amines

1985 • 61 citations

The monoamine oxidase inhibitors clorgyline and l-deprenyl also affect the uptake of dopamine, noradrenaline and serotonin by rat brain synaptosomal preparations

1980 • 61 citations

Mechanism of MPTP toxicity: more answers, more questions

1985 • 54 citations

Participation of brain monoamine oxidase B form in the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine: Relationship between the enzyme inhibition and the neurotoxicity

1985 • 53 citations

Effects of 1‐Methyl‐4‐Phenyl‐1,2,5,6‐Tetrahydropyridine and Related Compounds on the Uptake of [³H]3,4‐Dihydroxyphenylethylamine and [³H]5‐Hydroxytryptamine in Neostriatal Synaptosomal Preparations

1985 • 51 citations

The effects of pyridinium salts, structurally related compounds of 1-methyl-4-phenylpyridinium ion (MPP+), on tyrosine hydroxylation in rat striatal tissue slices

1986 • 43 citations

The toxic actions of MPTP and its metabolite MPP+ are not mimicked by analogues of MPTP lacking an N-methyl moiety

1985 • 35 citations

Behavioral and biochemical changes following acute administration of MPTP and MPP+

1987 • 28 citations

Inhibition of rat brain monoamine oxidase by some analogues of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and 1-methyl-4-phenylpyridinium ion

1986 • 25 citations

Intracerebroventricular administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and its metabolite 1-methyl-4-phenylpyridinium ion (MPP+) decrease dopamine and increase acetylcholine in the mouse neostriatum

1985 • 22 citations

Time-dependent inhibition of rat brain monoamine oxidase by an analogue of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP),4-(4-chlorophenyl)-1,2,3,6-tetrahydropyridine

1986 • 10 citations

Relations between MPTP (1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine), the Neurotoxin MPP+ (1-Methyl-4-Phenylpyridinium Ion), and MAO in Rat Brain

1985 • 5 citations