Identification and Characterization of Two Upstream Elements that Regulate Adrenocortical Expression of Steroid 11β-Hydroxylase

Rapid and efficient site-specific mutagenesis without phenotypic selection.

1985 • 7,573 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

Congenital Adrenal Hyperplasia

2003 • 1,390 citations

Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene

1987 • 1,364 citations

Human growth hormone as a reporter gene in regulation studies employing transient gene expression.

1986 • 667 citations

A High-Efficiency HeLa Cell Nuclear Transcription Extract

1988 • 612 citations

Naturally occurring poly(dA-dT) sequences are upstream promoter elements for constitutive transcription in yeast.

1985 • 526 citations

Characterization of two genes encoding human steroid 11 beta-hydroxylase (P-450(11) beta).

1989 • 440 citations

Tissue-specific enhancer of the human glycoprotein hormone alpha-subunit gene: dependence on cyclic AMP-inducible elements.

1987 • 409 citations

Interaction of a common cellular transcription factor, ATF, with regulatory elements in both E1a- and cyclic AMP-inducible promoters.

1988 • 290 citations

Human Growth Hormone as a Reporter Gene in Regulation Studies Employing Transient Gene Expression

1986 • 223 citations

Isolation of Aldosterone Synthase Cytochrome P-450 from Zona Glomerulosa Mitochondria of Rat Adrenal Cortex

1989 • 141 citations

Activation of yeast RNA polymerase II transcription by a thymidine-rich upstream element in vitro.

1989 • 116 citations

A cAMP-responsive Element Regulates Expression of the Mouse Steroid 11β-Hydroxylase Gene

1989 • 76 citations

Structural and Functional Analysis of the Promoter Region of the Gene Encoding Mouse Steroid 11β-Hydroxylase

1989 • 66 citations

The roles of cAMP and cAMP-dependent Protein Kinase in the Expression of Cholesterol Side Chain Cleavage and Steroid 11β-Hydroxylase Genes in Mouse Adrenocortical Tumor Cells

1989 • 62 citations

Expression of Two Kinds of Cytochrome P-450(11β) mRNA in Bovine Adrenal Cortex

1988 • 60 citations

Congenital Adrenal Hyperplasia

2013 • 2 citations