Pharmaco-behavioral effects of hypothalamic peptides in animals and man: focus on thyrotropin-releasing hormone and neurotensin

The Isolation of a New Hypotensive Peptide, Neurotensin, from Bovine Hypothalami

1973 • 1,501 citations

Amphetamine Psychosis: A "Model" Schizophrenia Mediated by Catecholamines

1973 • 590 citations

EFFECTS OF THYROTROPIN-RELEASING HORMONE IN DEPRESSION*1

1972 • 558 citations

The identity of chemical and hormonal properties of the thyrotropin releasing hormone and pyroglutamyl-histidyl-proline amide

1969 • 530 citations

Thyrotropin-Releasing Hormone: Regional Distribution in Rat Brain

1974 • 421 citations

The amino acid sequence of a hypothalamic peptide, neurotensin.

1975 • 415 citations

Regional distribution of neurotensin and somatostatin in rat brain

1977 • 408 citations

Enhancement of Imipramine Antidepressant Activity by Thyroid Hormone

1969 • 392 citations

Thyrotropin-Releasing Hormone in Specific Nuclei of Rat Brain

1974 • 378 citations

Neurotensin: immunohistochemical localization in rat central nervous system.

1977 • 341 citations

Hypothermia and intolerance to cold induced by intracisternal administration of the hypothalamic peptide neurotensin

1976 • 312 citations

The Effect of Glucocorticoid Administration on Human Pituitary Secretion of Thyrotropin and Prolactin

1976 • 303 citations

Bombesin: Potent Effects on Thermoregulation in the Rat

1977 • 300 citations

Distribution and Concentration of TRH in the Rat Brain¹²

1974 • 300 citations

Effects of thyrotropin-releasing hormone (TRH) on the actions of pentobarbital and other centrally acting drugs.

1975 • 292 citations

Thyrotropin Releasing Hormone: Enhancement of Dopa Activity by a Hypothalamic Hormone

1972 • 283 citations

Growth Hormone and Prolactin Release After Injection of Thyrotropin-Releasing Hormone in Patients with Depression

1975 • 266 citations

Neurotensin: Central nervous system effects of a hypothalamic peptide

1977 • 260 citations

Neurotensin: specific binding to synaptic membranes from rat brain.

1977 • 257 citations

Depressive Disease

1971 • 252 citations

Regional and subcellular distributions of brain neurotensin

1976 • 237 citations

Effect of Neurotensin, Substance P and Morphine Sulfate on the Secretion of Prolactin and Growth Hormone in the Rat

1977 • 230 citations

Enhancement of cerebral noradrenaline turnover by thyrotropin-releasing hormone

1974 • 221 citations

Thyrotropin releasing hormone: Antagonism of pentobarbital in rodents

1974 • 213 citations

Radioimmunoassay for neurotensin, a hypothalamic peptide.

1976 • 211 citations

Alcoholism and Depression

1973 • 211 citations

Neurotensin, a central nervous system peptide: apparent receptor binding in brain membranes

1977 • 209 citations

Thyrotropin releasing hormone (TRH): Apparent receptor binding in rat brain membranes

1975 • 205 citations

SUPPRESSION OF FEEDING AND DRINKING ACTIVITY IN RATS FOLLOWING INTRAVENTRICULAR INJECTION OF THYROTROPIN RELEASING HORMONE (TRH)¹¹

1977 • 202 citations

EFFECTS OF NEUROTENSIN AND SUBSTANCE P ON PLASMA INSULIN, GLUCAGON AND GLUCOSE LEVELS.

1976 • 189 citations

Antagonism of ethanol narcosis by thyrotropin releasing hormone

1974 • 170 citations

Evidence for a direct effect of LRF and TRF on single unit activity in the rostral hypothalamus

1974 • 165 citations

In vitro biosynthesis of TSH- and LH-releasing factors by the human placenta

1975 • 163 citations

Electrically Induced Convulsions

1940 • 150 citations

CENTRAL NERVOUS SYSTEM EFFECTS OF HYPOTHALAMIC PEPTIDES

1975 • 143 citations

Abnormal TSH, PRL and GH Response to TSH Releasing Factor in Chronic Renal Failure

1976 • 141 citations

Evidence for immunoreactive neurotensin in dog intestinal mucosa

1976 • 139 citations

Thyrotropin releasing hormone (TRH): depressant action on central neuronal activity

1975 • 139 citations

Thyroid-Hormone Enhancement of Imipramine in Nonretarded Depressions

1970 • 138 citations

Inhibition of gastric acid secretion in dogs by neurotensin

1976 • 137 citations

Distribution, localization and characteristics of neurotensin binding sites in the rat brain

1977 • 121 citations

Thyroid Function and the Response to Liothyronine in Depression

1972 • 116 citations

Thyrotropin-Releasing Hormone: Stimulation of Colonic Activity Following Intracerebroventricular Administration

1977 • 115 citations

TRH potentiates excitatory actions of acetylcholine on cerebral cortical neurones

1976 • 115 citations

TRH: a possible mediator of thermoregulation

1974 • 115 citations

Investigations into the mechanism of reduction of ethanol sleep by thyrotropin-releasing hormone (TRH).

1976 • 112 citations

Protirelin Stimulation Test and Thyroid Function During Treatment of Depression

1975 • 111 citations

A possible mechanism for the anti-depressant activity of thyrotropin releasing hormone

1974 • 110 citations

Enhancement of Imipramine by Thyroid Stimulating Hormone: Clinical and Theoretical Implications

1970 • 105 citations

Actions of bombesin, thyrotropin releasing factor, prostaglandin E2 and naloxone on thermoregulation in the rat

1977 • 103 citations

Neurotensin-induced hypothermia in the rat: Structure-activity studies

1978 • 98 citations

Hyperglycemic Effect of Neurotensin, a Hypothalamic Peptide*

1976 • 98 citations

Substance P and Neurotensin

1977 • 95 citations

Fasting Blunts the TSH Response to Synthetic Thyrotropin-Releasing Hormone (TRH)

1975 • 94 citations

Thyrotropin-Releasing Hormone Stimulation and Somatostatin Inhibition of Growth Hormone Secretion from Perfused Rat Adenohypophyses*

1974 • 89 citations

TRH potentiates behavioural changes following increased brain 5-hydroxytryptamine accumulation in rats

1974 • 88 citations

The role of TRH in the neoteny of the Mexican axolotl (Ambystoma mexicanum)

1974 • 85 citations

THR (Lopremone): Psychobiological Responses of Normal Women

1973 • 83 citations

Prostaglandin Levels in Tissues of the Male Reproductive System in Six Strains of Mice

1975 • 81 citations

Hyperglycemia and hyperglucagonemia following neurotensin administration

1976 • 80 citations

TRH-like immunoreactivity in urine, serum and extrahypothalamic brain: Non-identity with synthetic pyrogluhhist-pro-NH2 (TRH)

1978 • 76 citations

Subcellular distribution of thyrotropin-releasing hormone (TRH) in rat brain and hypothalamus

1977 • 74 citations

Thyrotropin releasing hormone (TRH): Distribution in the brain, blood and urine of the rat

1974 • 74 citations

THYROTROPHIN-RELEASING HORMONE IN SCHIZOPHRENIA

1973 • 71 citations

Modification of pentobarbital effects by natural and synthetic polypeptides: Dissociation of brain and pituirary effects

1975 • 68 citations

Peptides and the Central Nervous System

1978 • 68 citations

Hypothalamic Hypophysiotropic Hormones

1975 • 65 citations

Site of inactivation of thyrotropin-releasing hormone by human plasma

1971 • 64 citations

Thyrotropin releasing hormone: Enhancement of dopa activity in thyroidectomized rats

1974 • 61 citations

An Analysis of the Function of Drugs in the Stimulus Control of Operant Behavior

1971 • 61 citations

Action of two hypothalamic factors (TRH, MIF) and of angiotensin II on the behavioral effects of L-DOPA and 5-hydroxytryptophan in mice

1974 • 61 citations

Hypothalamic Releasing Factors and Parkinson Disease

1974 • 60 citations

Effects of thyrotropin-releasing hormone (TRH) microinjected into various brain areas of conscious and pentobarbital-pretreated rabbits

1976 • 57 citations

Thyroid stimulating hormone response after thyrotropin releasing hormone in depressed, schizophrenic and normal women

1977 • 56 citations

Thyrotropin-releasing hormone in schizophrenia

1975 • 54 citations

TRH-like immunoreactivity in rat pancreas and eye, bovine and sheep pineals, and human placenta: Non-identity with synthetic Pyroglu-His-Pro-NH2 (TRH)

1979 • 54 citations

Thyrotropin releasing hormone

1984 • 53 citations

Thyrotropin Responses to TRH in Depressive Illness: Relation to Clinical Subtypes and Prolonged Duration of Depressive Episode

1974 • 52 citations

Release of Luteinizing Hormone Releasing Hormone and Thyrotropin Releasing Hormone from a Synaptosome-Enriched Fraction of Hypothalamic Homogenates¹

1977 • 51 citations

Enhancement of cerebral noradrenaline turnover by thyrotropin-releasing hormone: Evidence by fluorescence histochemistry

1974 • 51 citations

Interactions of thyrotropin releasing hormone and morphine sulfate in rodents

1977 • 50 citations

Intensification of central catecholaminergic and serotonergic processes by the hypothalamic factors MIF and TRF and by angiotensin II

1975 • 49 citations

Norepinephrine metabolism in the rat brain following acute and chronic administration of thyrotropin releasing hormone

1974 • 46 citations

Neurotensin and substance-P: Effects on plasma insulin and glucagon levels

1976 • 45 citations

Transport of Thyrotropin-Releasing Hormone from Cerebrospinal Fluid to Hypophysial Portal Blood and the Release of Thyrotropin

1975 • 45 citations

Thyrotropin releasing hormone: antagonism of pentobarbital narcosis in the monkey

1976 • 45 citations

Thyrotropin-releasing hormone: differential antidepressant and endocrinological effects

1976 • 44 citations

Localization of Thyrotropin-Releasing Factor (TRF) in the Hypothalamus of the Rat

1974 • 43 citations

Tremorogenic effect of thyrotropin releasing hormone in rats

1974 • 42 citations

Growth Hormone Release in the Rat: Effects of Somatostatin and Thyrotropin- Releasing Factor

1975 • 41 citations

Plasma Growth Hormone Responses to Thyrotropin-Releasing Hormone in the Urethane-Anesthetized Rat

1975 • 40 citations

RADIOIMMUNOASSAY OF THYROTROPIN-RELEASING HORMONE (TRH) IN HUMAN PLASMA AND URINE

1974 • 40 citations

Profil de la T.R.H. en psychopharmacologie exp�rimentale

1975 • 39 citations

Pituitary responses to thyrotropin releasing hormone in depressed patients: A review

1976 • 39 citations

Thyrotropin-releasing hormone (TRH)-induced hyperthermia and behavioral excitation in rabbits.

1975 • 37 citations

CHARACTERIZATION OF HYPOTHALAMIC SUBCELLULAR PARTICLES CONTAINING LUTEINIZING HORMONE RELEASING HORMONE AND THYROTROPIN RELEASING HORMONE

1976 • 34 citations

The contrasting actions of TRH and cycloheximide in altering the effects of centrally acting drugs: Evidence for the non-involvement of dopamine sensitive adenylate cyclase

1976 • 34 citations

Neonatal treatment with TRH affects development, learning, and emotionality in the rat

1976 • 34 citations

Failure of thyrotropin releasing hormone to increase 125I uptake by the thyroid in Rana temporaria

1974 • 34 citations

The effects of thyrotropin-releasing hormone on the behaviour of rats pretreated with α-methyltyrosine

1975 • 30 citations

Thyrotropin releasing hormone (TRH): DOPA potentiation and biogenic amine studies

1975 • 28 citations

Studies on Pituitary Hormones and Releasing Hormones in Depression and Sexual Impotence

1975 • 26 citations

Preliminary studies on the use of thyrotropin releasing hormone in manic states, depression, and the dysphoria of alcohol withdrawal.

1975 • 24 citations

Effects of thyrotropin-releasing hormone in schizophrenia.

1975 • 22 citations

Evaluation of thyrotropin-releasing hormone as a potential antidepressant agent in the conscious dog

1973 • 20 citations

Effect of hypothalamic hormones on the concentration of adenosine 3′, 5′-monophosphate in incubated rat pineal glands

1976 • 19 citations

Thyrotropin releasing hormone (TRH): Restoration of oxotremorine tremor in mice

1976 • 19 citations

Synthetic thyroid releasing hormone (TRH) administered orally to chronic schizophrenic patients.

1975 • 16 citations

Effect of thyrotropin-releasing hormone (TRH) and antidepressant agents on brain stem and hypothalamic multiple unit activity in the cat

1976 • 16 citations

Distribution of Thyrotropin-Releasing Hormone in Human Brain

1976 • 15 citations

Inhibition of Pentobarbital-Induced Release of Growth Hormone by Thyrotropin Releasing Hormone

1975 • 15 citations

Electrophysiological Mapping of Brain Sites Sensitive to Corticosteroids, ACTH, and Hypothalamic Releasing Hormones

2015 • 15 citations

Effects of Thyrotropin-Releasing Hormone in Minimal Brain Dysfunction

1975 • 13 citations

Antagonism of isolation-induced aggression in mice by thyrotropin-releasing hormone (TRH)

1976 • 12 citations

Bioassay and Toxicology of TRH

2015 • 12 citations

Parameters of Alteration of Pentobarbital Response by Hypothalamic Polypeptides

1975 • 9 citations

Enhancement of noradrenaline responses by thyrotropine-releasing hormone

1975 • 8 citations

Lack of effect of chronically administered thyrotropin-releasing hormone (TRH) on regional rat brain tyrosine hydroxylase activity

1977 • 8 citations

Effects of administration of thyrotropin-releasing hormone in parkinsonism

1974 • 6 citations

Interaction of the Tripeptide Pyroglutamyl-Histidyl-Proline Amide (Thyrotropin-Releasing Hormone) with Brain Norepinephrine Metabolism: Evidence for an Extrahypophyseal Action of TRH on Central Nervous System Function

1975 • 6 citations

Monoiodotyrosine: Effects on Tissue Amines and Cold Survival

1976 • 5 citations

Microiontophoresis of Thyrotropin-Releasing Hormone (TRH). Effects on the Activity of Central Neurons

2015 • 3 citations