Polymorphism in the P-glycoprotein drug transporter MDR1 gene: a possible link between environmental and genetic factors in Parkinson's disease.

Parkinsonism

1967 • 11,463 citations

Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo

2000 • 2,358 citations

Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs

1994 • 2,255 citations

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs.

1996 • 1,268 citations

The Prevention of Acute Gastric Ulcer in the Rat by α-Methyldopa

1967 • 784 citations

Frequency of single nucleotide polymorphisms in the P-glycoprotein drug transporter MDR1 gene in white subjects

2001 • 757 citations

The risk of Parkinson's disease with exposure to pesticides, farming, well water, and rural living

1998 • 630 citations

Environmental risk factors and Parkinson's disease

1997 • 605 citations

Expression of P-glycoprotein in human placenta: relation to genetic polymorphism of the multidrug resistance (MDR)-1 gene.

2001 • 538 citations

Role of P-Glycoprotein in Drug Disposition

2000 • 254 citations

Variability and validity of polymorphism association studies in Parkinson’s disease

2000 • 222 citations

P-Glycoprotein Deficiency in a Subpopulation of CF-1 Mice Enhances Avermectin-Induced Neurotoxicity

1997 • 203 citations

Expression polymorphism of the blood???brain barrier component P-glycoprotein (MDR1) in relation to Parkinson's disease

2002 • 179 citations

Candidate genes and Parkinson’s disease

1999 • 17 citations

N-acetyltransferase 2 polymorphism in sporadic Parkinson's disease in a Polish population

2002 • 14 citations

P-Glycoprotein, Multidrug-Resistance-Associated Protein and Parkinson’s Disease

2001 • 10 citations