Dopamine receptor polymorphisms and drug response in schizophrenia

Dopamine in schizophrenia: a review and reconceptualization

1991 • 1,963 citations

Does Fast Dissociation From the Dopamine D₂ Receptor Explain the Action of Atypical Antipsychotics?: A New Hypothesis

2001 • 1,113 citations

Twin studies of schizophrenia: From bow-and-arrow concordances to Star Wars Mx and functional genomics

2000 • 898 citations

Important Issues in the Drug Treatment of Schizophrenia

1980 • 286 citations

Dopamine D3-receptor gene variant and susceptibility to tardive dyskinesia in schizophrenic patients

1997 • 242 citations

Proposed Schizophrenia-Related Gene Polymorphism: Expression of the Ser9Gly Mutant Human Dopamine D3Receptor with the Semliki Forest Virus System

1996 • 233 citations

Relationship between homozygosity at the dopamine D3 receptor gene and schizophrenia

1994 • 179 citations

Polymorphisms in dopamine receptors: what do they tell us?

2000 • 174 citations

Linkage and associated studies of schizophrenia

2000 • 151 citations

Allelic association between a Ser-9-Gly polymorphism in the dopamine D3 receptor gene and schizophrenia

1996 • 144 citations

Association of Short-Term Response to Haloperidol Treatment With a Polymorphism in the Dopamine D₂Receptor Gene

2001 • 138 citations

Dopamine D3 receptor gene polymorphism and response to clozapine in schizophrenic Pakistani patients

1999 • 121 citations

Allelic Variation in the D4 Dopamine Receptor (DRD4) Gene Does Not Predict Response to Clozapine

1994 • 113 citations

The dopamine D3 receptor (DRD3) Ser9Gly polymorphism and schizophrenia: a haplotype relative risk study and association with clozapine response

1998 • 109 citations

Extreme discordant phenotype methodology: an intuitive approach to clinical pharmacogenetics

2000 • 107 citations

Recent progress in psychiatric genetics--some hope but no hype

2000 • 104 citations

The relationship between dopamine D2 receptor polymorphism at the Taq1 A locus and therapeutic response to nemonapride, a selective dopamine antagonist, in schizophrenic patients

2000 • 101 citations

Lack of association between schizophrenia and alleles in the dopamine D₃ receptor gene

1993 • 100 citations

Association of TaqI A polymorphism of dopamine D2 receptor gene and tardive dyskinesia in schizophrenia

1997 • 98 citations

Pharmacogenetics of antipsychotic treatment: lessons learned from clozapine

2000 • 94 citations

Efficacy and Side-Effects of Clozapine: Testing for Association with Allelic Variation in the Dopamine D4 Receptor Gene

1996 • 92 citations

Epidemiology of Schizophrenia: A European Perspective

1986 • 88 citations

Polymorphisms of the dopamine D 4 receptor and response to antipsychotic drugs

1999 • 81 citations

Dopamine D4 receptor 48-bp repeat polymorphism: no association with response to antipsychotic treatment, but association with catatonic schizophrenia

2000 • 78 citations

Dopamine D4 receptor gene polymorphisms and neuroleptic response in schizophrenia

1998 • 77 citations

Dopamine D3 receptor gene variants and substance abuse in schizophrenia

1998 • 76 citations

Dopamine D4 receptor gene polymorphisms: relation to ethnicity, no association with schizophrenia and response to clozapine in Israeli subjects

1997 • 75 citations

Association study of schizophrenia with dopamine D3 receptor gene polymorphisms: Probable effects of family history of schizophrenia?

1993 • 73 citations

No association between schizophrenia and homozygosity at the D₃ dopamine receptor gene

1993 • 71 citations

Lack of association between a polymorphism in the promoter region of the dopamine-2 receptor gene and clozapine response

1998 • 68 citations

Analysis of clozapine response and polymorphisms of the dopamine D4 receptor gene (DRD4) in schizophrenic patients

1995 • 65 citations

The use of single nucleotide polymorphisms in the isolation of common disease genes

2000 • 57 citations

Association study of dopamine D3 receptor gene and schizophrenia

1995 • 56 citations

Evidence for an Association between the Dopamine D3 Receptor Gene DRD3 and Schizophrenia

1997 • 53 citations

DRD3 and DAT1 genes in schizophrenia: an association study

2000 • 53 citations

Pharmacogenetics of schizophrenia

2000 • 52 citations

Association study of schizophrenia and the dopamine D3 receptor gene locus in two independent samples

1996 • 49 citations

Polymorphisms of dopamine D2-like (D2, D3, and D4) receptors in schizophrenia

1996 • 46 citations

Pharmacogenomics and schizophrenia

2000 • 45 citations

Assessment of association of D3 dopamine receptorMscI polymorphism with schizophrenia: Analysis of symptom ratings, family history, age at onset, and movement disorders

1996 • 44 citations

Application of pharmacogenetics to psychotic disorders: the first consensus conference1Participants (in alphabetical order): A. Breier, L.E. DeLisi, F. Henn, W. Kalow, R. Kerwin, J. Kurth, B. Lerer, A. Malhotra, M. Masellis, H.J. Möller, V. Ozdemir, J. Peuskens, N.R. Schooler, V.M. Steen.12Conference organizers: M. Rietschel, J.L. Kennedy, F. Macciardi, H.Y. Meltzer.23Section Chairs: J.M. Kane and H.Y. Meltzer, J.L. Kennedy and S. Marder, F. Macciardi and M.M. Nöthen, A.G. Awad.3

1999 • 34 citations

Homozygosity at the dopamine D3 receptor gene in schizophrenic patients

1996 • 26 citations

Future directions of research in statistical genetics

2000 • 17 citations

Variability in Response to Clozapine: Potential Role of Cytochrome P450 1A2 and the Dopamine D₄Receptor Gene

1999 • 17 citations

Functional neuroimaging and pharmacogenetic studies of clozapine's action at dopamine receptors.

1994 • 12 citations

Dopamine Receptors: Novel Insights from Biochemical and Genetic Studies

2000 • 8 citations