Conformational flexibility: a new concept for explaining binding and biological properties of iduronic acid-containing glycosaminoglycans

Structure-activity relationship in heparin: A synthetic pentasaccharide with high affinity for antithrombin III and eliciting high anti-factor Xa activity

1983 • 651 citations

Further characterization of the antithrombin-binding sequence in heparin

1982 • 450 citations

Structure and Biological Activity of Heparin

1985 • 431 citations

Biosynthesis of heparin

1986 • 245 citations

Evidence for conformational equilibrium of the sulfated L-iduronate residue in heparin and in synthetic heparin mono- and oligo-saccharides: NMR and force-field studies

1986 • 228 citations

STRUCTURAL STUDIES ON A BIOLOGICALLY ACTIVE HEXASACCHARIDE OBTAINED FROM HEPARIN

1981 • 225 citations

Structure and function of cell-associated proteoglycans

1987 • 197 citations

Studies on the Conformation of Heparin by ¹H and ¹³C NMR Spectroscopy

1979 • 121 citations

Mono- and bidimensional 500 MHz 1H-NMR spectra of a synthetic pentasaccharide corresponding to the binding sequence of heparin to antithrombin-III: Evidence for conformational peculiarity of the sulfated iduronate residue

1985 • 113 citations

Periodate oxidation and the shapes of glycosaminoglycuronans in solution

1978 • 104 citations

A force‐field study of the conformational characteristics of the iduronate ring

1986 • 94 citations

Conformational equilibria of α-L-iduronate residues in disaccharides derived from heparin

1987 • 90 citations

Conformational analysis of synthetic heparin‐like oligosaccharides containing α‐L‐idopyranosyluronic acid

1987 • 77 citations

Heparin-polypeptide interactions in aqueous solution

1973 • 63 citations

Structural factors in cation binding to anionic polysaccharides of connective tissue

1964 • 49 citations

Binding of heparin fractions and other polysulfated polysaccharides to plasma fibronectin: effects of molecular size and degree of sulfation of polysaccharides.

1985 • 35 citations

Resolution-enhanced 1H-n.m.r. spectra of dermatan sulfate and chondroitin sulfates: conformation of the uronic acid residues

1979 • 35 citations

Conformation of the pentasaccharide corresponding to the binding site of heparin to Antithrombin-III

1987 • 34 citations

Controversial glycosaminoglycan conformations

1985 • 33 citations

Binding of heparin fractions and other polysulfated polysaccharides to plasma fibronectin: effects of molecular size and degree of sulfation of polysaccharides

1985 • 25 citations

Conformational equilibrium of unsulphated iduronate in heparan sulphate tetrasaccharides

1985 • 24 citations

N.M.R. studies of the disulphated disaccharide obtained by degradation of bovine lung heparin with nitrous acid

1985 • 22 citations

Solid-state 13C NRM and X-ray diffraction of dermatan sulfate

1986 • 14 citations