Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation

Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.

1993 • 2,370 citations

Simplified mammalian DNA isolation procedure

1991 • 1,508 citations

Deletion of a DNA Polymerase β Gene Segment in T Cells Using Cell Type-Specific Gene Targeting

1994 • 1,396 citations

Essential Role for TrkB Receptors in Hippocampus-Mediated Learning

1999 • 797 citations

An abundance of X-linked genes expressed in spermatogonia

2001 • 778 citations

Xist-deficient mice are defective in dosage compensation but not spermatogenesis.

1997 • 705 citations

Targeted oncogene activation by site-specific recombination in transgenic mice.

1992 • 687 citations

Hybrid vigor, fetal overgrowth, and viability of mice derived by nuclear cloning and tetraploid embryo complementation

2001 • 621 citations

Rapid Colorectal Adenoma Formation Initiated by Conditional Targeting of the Apc Gene

1997 • 580 citations

Y-encoded, species-specific DNA in mice: Evidence that the Y chromosome exists in two polymorphic forms in inbred strains

1984 • 233 citations

Trisomy eight in ES cells is a common potential problem in gene targeting and interferes with germ line transmission

1997 • 184 citations

Molecular cloning and sequence analysis of a mouse Y chromosome RNA transcript expressed in the test is

1987 • 115 citations

The Herpes Simplex Virus Type 1 Thymidine Kinase Is Expressed in the Testes of Transgenic Mice under the Control of a Cryptic Promoter

1991 • 84 citations

XO mice

1962 • 81 citations

The herpes simplex virus type 1 thymidine kinase is expressed in the testes of transgenic mice under the control of a cryptic promoter.

1991 • 73 citations

Karyotyping mouse chromosomes by multiplex-FISH (M-FISH).

2001 • 37 citations

Isolation, culture, and manipulation of embryonic stem cells

1994 • 16 citations

X-chromosome segregation, maternal age and aneuploidy in the XO mouse

1983 • 15 citations

Flp recombinase regulated lacZ expression at the ROSA26 locus

2002 • 12 citations