Inhibitory effect of the angiogenesis inhibitor TNP-470 on tumor growth and metastasis in nude mice bearing human hepatocellular carcinoma

Tumor Angiogenesis and Metastasis — Correlation in Invasive Breast Carcinoma

1991 • 5,657 citations

Synthetic analogues of fumagillin that inhibit angiogenesis and suppress tumour growth

1990 • 1,308 citations

PROTOCOLS FOR SCREENING CHEMICAL AGENTS AND NATURAL PRODUCTS AGAINST ANIMAL TUMORS AND OTHER BIOLOGICAL SYSTEMS

1972 • 1,130 citations

The implications of angiogenesis for the biology and therapy of cancer metastasis

1994 • 1,120 citations

Tumor Angiogenesis

1985 • 1,038 citations

Quantitative relationships of intravascular tumor cells, tumor vessels, and pulmonary metastases following tumor implantation.

1974 • 775 citations

Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules.

1988 • 680 citations

The prognostic significance of tumor vascularity in intermediate-thickness (0.76-4.0 mm thick) skin melanoma. A quantitative histologic study.

1988 • 538 citations

Potent anti-angiogenic action of AGM-1470: comparison to the fumagillin parent

1991 • 324 citations

Inhibitory effect of angiogenesis inhibitor TNP-470 on tumor growth and metastasis of human cell lines in vitro and in vivo.

1993 • 207 citations

Inhibition of tumor growth and metastasis of rodent tumors by the angiogenesis inhibitor O-(chloroacetyl-carbamoyl)fumagillol (TNP-470; AGM-1470).

1993 • 164 citations

Angiogenesis inhibitor TNP-470 (AGM-1470) potently inhibits the tumor growth of hormone-independent human breast and prostate carcinoma cell lines.

1993 • 163 citations

Establishment of a metastatic model of human hepatocellular carcinoma in nude mice via orthotopic implantation of histologically intact tissues

1996 • 159 citations

Prevention of hepatic metastasis of human colon cancer by angiogenesis inhibitor TNP-470.

1995 • 105 citations

Enhanced suppression of tumor growth by combination of angiogenesis inhibitor O-(chloroacetyl-carbamoyl)fumagillol (TNP-470) and cytotoxic agents in mice.

1994 • 98 citations

Suppression of pulmonary metastasis by angiogenesis inhibitor TNP‐470 in murine osteosarcoma

1995 • 75 citations

Chemosensitivity testing of fresh human gastric cancer with highly purified tumour cells using the MTT assay

1992 • 72 citations

Antitumor effects of angiogenesis inhibitor TNP-470 in rabbits bearing VX-2 carcinoma by arterial administration of microspheres and oil solution.

1993 • 50 citations

Clinical trials of antiangiogenic agents

1995 • 45 citations

Antitumour effect of a synthetic analogue of fumagillin on murine renal carcinoma

1994 • 35 citations

The role of angiogenesis in the tumor growth of Syrian hamster pancreatic cancer cell line HPD-NR

1995 • 31 citations