Oligosaccharide structure and amino acid sequence of the major glycopeptides of mature human .beta.-hexosaminidase

ASSEMBLY OF ASPARAGINE-LINKED OLIGOSACCHARIDES

1985 • 4,790 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

LYSOSOMAL ENZYMES AND THEIR RECEPTORS

1986 • 915 citations

Biosynthesis of lysosomal enzymes in fibroblasts. Phosphorylation of mannose residues.

1980 • 404 citations

Fibroblasts from patients with I-cell disease and pseudo-Hurler polydystrophy are deficient in uridine 5'-diphosphate-N-acetylglucosamine: glycoprotein N-acetylglucosaminylphosphotransferase activity.

1981 • 323 citations

Cloning and sequence analysis of cDNA for human cathepsin D.

1985 • 318 citations

The substrate specificities of endo-β-N-acetylglucosaminidases CII and H

1977 • 197 citations

Cloning, sequencing, and expression of cDNA for human beta-glucuronidase.

1987 • 180 citations

Isolation of cDNA clones coding for the alpha-subunit of human beta-hexosaminidase. Extensive homology between the alpha- and beta-subunits and studies on Tay-Sachs disease.

1986 • 176 citations

[24] Techniques in enzymic hydrolysis

1967 • 166 citations

Lysosomal enzyme phosphorylation. Recognition of a protein-dependent determinant allows specific phosphorylation of oligosaccharides present on lysosomal enzymes.

1984 • 150 citations

The subunit and polypeptide structure of hexosaminidases from human placenta

1980 • 115 citations

Proteolytic processing of pro-alpha and pro-beta precursors from human beta-hexosaminidase. Generation of the mature alpha and beta a beta b subunits.

1988 • 79 citations

Molecular cloning of a cDNA for human alpha-L-fucosidase.

1985 • 78 citations

Identification of cDNA clones encoding a precursor of rat liver cathepsin B.

1985 • 73 citations

Determination of the structure of four glycopeptides from hen ovalbumin using 360-MHz proton magnetic resonance

1981 • 71 citations

Oligosaccharide units of lysosomal cathepsin D from porcine spleen. Amino acid sequence and carbohydrate structure of the glycopeptides.

1983 • 68 citations

Proteolytic processing of the alpha-chain of the lysosomal enzyme, beta-hexosaminidase, in normal human fibroblasts.

1988 • 63 citations

Nucleotide sequence of rat preputial gland beta-glucuronidase cDNA and in vitro insertion of its encoded polypeptide into microsomal membranes.

1986 • 61 citations

Fabry disease: isolation of a cDNA clone encoding human alpha-galactosidase A.

1985 • 59 citations

Novel carbohydrate structures of cathepsin B from porcine spleen.

1984 • 58 citations

Phosphorylation of the oligosaccharide of uteroferrin by UDP-GlcNAc:glycoprotein N-acetylglucosamine-1-phosphotransferases from rat liver, Acanthamoeba castellani, and Dictyostelium discoideum requires alpha 1,2-linked mannose residues.

1986 • 55 citations

Structure of the glycopeptides of a human γ₁-immunoglobulin G (Tem) myeloma protein as determined by 360-megahertz nuclear magnetic resonance spectroscopy

1982 • 45 citations

Recognition and receptor-mediated uptake of phosphorylated high mannose-type oligosaccharides by cultured human fibroblasts.

1983 • 32 citations

Localization of the pro‐sequence within the total deduced primary structure of human β‐hexosaminidase B

1988 • 20 citations

Application of high-field proton magnetic resonance spectroscopy in the structural determination of membrane-derived Sindbis virus glycopeptides

1981 • 16 citations

Characterization by nuclear magnetic resonance of the concanavalin A binding oligosaccharide on the β_b chain of placental β-hexosaminidase B: lectin binding to the separated polypeptide chains of hexosaminidases A and B

1985 • 10 citations