Crystal‐induced endogenous pyrogen production. A further look at gouty inflammation

Interleukin-1

1984 • 1,625 citations

An interleukin 1 like factor stimulates bone resorption in vitro

1983 • 1,017 citations

Stimulation of rheumatoid synovial cell collagenase and prostaglandin production by partially purified lymphocyte-activating factor (interleukin 1).

1981 • 614 citations

Chemoattractant Receptors on Phagocytic Cells

1984 • 236 citations

Clinical Science

1962 • 225 citations

Induction of interleukin 1 secretion and enhancement of humoral immunity by binding of human C5a to macrophage surface C5a receptors.

1982 • 217 citations

Chemotactic cytokines: the role of leukocytic pyrogen and epidermal cell thymocyte-activating factor in neutrophil chemotaxis.

1984 • 215 citations

Human leukocytic pyrogen induces release of specific granule contents from human neutrophils.

1978 • 206 citations

The inhibitory effect of polymyxin B on endotoxin-induced endogenous pyrogen production

1982 • 179 citations

CRYSTAL-INDUCED INFLAMMATION IN CANINE JOINTS

1966 • 175 citations

APATITE ASSOCIATED DESTRUCTIVE ARTHRITIS

1984 • 126 citations

In vitro activation of human chondrocytes and synoviocytes by a human interleukin‐1‐like factor

1984 • 125 citations

A Functional Differentiation of Human Neutrophil Granules: Generation of C5a by a Specific (Secondary) Granule Product and Inactivation of C5a by Azurophil (Primary) Granule Products

1977 • 117 citations

Stimulation of neutrophil oxygen-dependent metabolism by human leukocytic pyrogen.

1979 • 114 citations

The pathology of gout.

1957 • 112 citations

A comparison of the duration of local anti-inflammatory effect of several adrenocorticosteroid esters--a bioassay technique.

1963 • 88 citations

A Modified Calcium Phosphate for Column Chromatography of Polynucleotides and Proteins¹

1959 • 87 citations

Suppression of urate crystal‐induced canine joint inflammation by heterologous anti‐polymorphonuclear leukocyte Serum

1968 • 84 citations

Mechanism of Action of Colchicine in Acute Urate Crystal-Induced Arthritis

1979 • 77 citations

The detection of endotoxin by in vitro production of endogenous pyrogen: Comparison with limulus amebocyte lysate gelation

1982 • 74 citations

The old and new concepts of acute gouty arthritis

1962 • 72 citations

Milwaukee shoulder syndrome: Eleven additional cases with involvement of the knee in seven (basic calcium phosphate crystal deposition disease)

1984 • 65 citations

Plasma Protein Binding by Monosodium Urate Crystals

1983 • 64 citations

Macrophage Factor that Induces Neutral Protease Secretion by Normal Rabbit Chondrocytes

1980 • 63 citations

The action of colchicine in acute gouty arthritis

1975 • 61 citations

Self-associating IgG rheumatoid factors stimulate monocytes to release prostaglandins and mononuclear cell factor that stimulates collagenase and prostaglandin production by synovial cells

1983 • 54 citations

Hydroxyapatite for chromatography

1978 • 47 citations

Clearance of calcium pyrophosphate dihydrate crystals in vivo

1979 • 45 citations

Acute polyarticular gout.

1983 • 43 citations

The fever of gout: urate crystals activate endogenous pyrogen production from human and rabbit mononuclear phagocytes.

1983 • 42 citations

Clearance of calcium pyrophosphate dihydrate crystals in vivo

1979 • 40 citations

Membrane properties and esterase activity of synovial lining cells: further evidence for a mononuclear phagocyte subpopulation.

1982 • 34 citations

Further comparisons of endogenous pyrogens and leukocytic endogenous mediators

1983 • 22 citations

Stimulation of secretion of collagenase and prostaglandin E2 by synovial fibroblasts in response to crystals of monosodium urate monohydrate: a model for joint destruction in gout.

1981 • 16 citations

The search for an endogenous activator.

1985 • 3 citations