A Comparative Review of the Adverse Effects of Anticonvulsants in Children with Epilepsy

Drug-Induced Hepatotoxicity

2003 • 1,591 citations

Valproic acid hepatic fatalities

1987 • 491 citations

Valproic acid hepatic fatalities. III. U.S. experience since 1986

1996 • 329 citations

Psychologic and Behavioral Effects of Antiepileptic Drugs in Children: A Double-Blind Comparison Between Phenobarbital and Valproic Acid

1987 • 270 citations

Exacerbation of Seizures in Children by Carbamazepine

1985 • 238 citations

Carbamazepine Side Effects in Children and Adults

1987 • 228 citations

Side effects of phenobarbital in toddlers; behavioral and cognitive aspects

1979 • 227 citations

Lamotrigine in Treatment of 120 Children with Epilepsy

1994 • 218 citations

THE HYPERKINETIC SYNDROME IN EPILEPTIC CHILDREN

1955 • 209 citations

Withdrawal of antiepileptic medication in children–effects on cognitive function

1993 • 200 citations

Antiepileptic Drugs, 4th Ed

1996 • 186 citations

Lamotrigine

1992 • 184 citations

Fatal Liver Failure in 16 Children with Valproate Therapy

1988 • 162 citations

Lamotrigine for the treatment of epilepsy in childhood

1995 • 153 citations

Clinical Side Effects of Phenobarbital, Primidone, Phenytoin, Carbamazepine, and Valproate During Monotherapy in Children

1988 • 149 citations

Behavioral Side Effects of Gabapentin in Children

1996 • 148 citations

Myoclonic, atonic, and absence seizures following institution of carbamazepine therapy in children

1983 • 146 citations

Severe Hepatotoxicity During Valproate Therapy: An Update and Report of Eight New Fatalities

1994 • 132 citations

Cognitive Impairment in New Cases of Epilepsy Randomly Assigned to Carbamazepine, Phenytoin and Sodium Valproate

1991 • 132 citations

Gabapentin

1995 • 132 citations

Gabapentin Toxicity in Children Manifesting as Behavioral Changes

1995 • 126 citations

Tiagabine: The Safety Landscape

1995 • 122 citations

Vigabatrin in Childhood Epilepsy

1991 • 115 citations

Valproate‐mediated disturbances of hemostasis

1994 • 102 citations

Felbamate in the Treatment of Lennox‐Gastaut Syndrome: Results of a 12‐Month Open‐Label Study Following a Randomized Clinical Trial

1993 • 101 citations

Efficacy and Adverse Effects of Established and New Antiepileptic Drugs*

1995 • 101 citations

Clinical and EEG response to anticonvulsants in neonatal seizures.

1989 • 100 citations

Fixed Drug Combinations and the Displacement of Bilirubin from Albumin

1971 • 93 citations

Comparison of Antiepileptic Drugs on Cognitive Function in Newly Diagnosed Epileptic Children: A Psychometric and Neurophysiological Study

1996 • 88 citations

Sodium Valproate, Platelet Dysfunction, and Bleeding

1981 • 87 citations

The potential for increasing seizure frequency, relapse, and appearance of new seizure types with vigabatrin.

1993 • 85 citations

Psychological effects of sodium valproate and carbamazepine in epilepsy.

1992 • 82 citations

International review of drugs in acute porphyria—1980

1980 • 72 citations

Pharmacokinetics of lorazepam in critically ill neonates with seizures

1992 • 66 citations

Effect of Sodium Valproate on Psychomotor Performance in Children as a Function of Dose, Fluctuations in Concentration, and Diagnosis

1987 • 65 citations

Behavioral and Cognitive Impairments in Children with Epilepsy: The Long-term Effects of Anticonvulsant Therapy

1985 • 60 citations

The role of vigabatrin in the management of infantile epileptic syndromes.

1993 • 60 citations

Felbamate

1995 • 52 citations

Lorazepam in the Treatment of Refractory Neonatal Seizures

1991 • 51 citations

Lorazepam in the Treatment of Refractory Neonatal Seizures

1986 • 45 citations

γ‐Vinyl‐GABA (Vigabatrin) in the Therapy of Lennox‐Gastaut Syndrome: An Open Study

1994 • 44 citations

Valproic acid and thrombocytopenia in children: A case-controlled retrospective study

1996 • 44 citations

Neurologic and neuro pathologic findings associated with marantic endo carditis in children and young adults

1980 • 42 citations

Gabapentin treatment of seizures in acute intermittent porphyria

1995 • 41 citations

Febrile convulsions: Intellectual progress in relation to anticonvulsant therapy and to recurrence of fits

1982 • 40 citations

Antipyrine metabolite kinetics in healthy human volunteers during multiple dosing of phenytoin and carbamazepine.

1985 • 38 citations

Carnitine-dependent changes of metabolic fuel consumption during long-term treatment with valproic acid

1994 • 38 citations

Phenytoin‐Induced Pseudolymphoma: Reevaluation Using Modern Molecular Biology Techniques

1996 • 36 citations

Abnormal metabolism of carnitine and valproate in a case of acute encephalopathy during chronic valproate therapy

1992 • 35 citations

Markedly Increased ω‐Oxidation of Valproate in Fulminant Hepatic Failure

1990 • 34 citations

Bromide treatment of pharmaco-resistant epilepsies with generalized tonic-clonic seizures: A clinical study

1992 • 32 citations

Effects of Phenytoin on Cognitive‐Motor Performance in Children as a Function of Drug Concentration, Seizure Type, and Time of Medication

1994 • 28 citations

Carbamazepine Therapy and LongTerm Prognosis in Epilepsy of Childhood

1989 • 20 citations

Reversal of the Adverse Chronic Effects of the Unsaturated Derivative of Valproic Acid—2-n-Propyl-4-Pentenoic Acid—on Ketogenesis and Liver Coenzyme A Metabolism by a Single Injection of Pantothenate, Carnitine, and Acetylcysteine in Developing Mice

1993 • 18 citations

Cyanosis, Cough, and Hypotension Following Intravenous Administration of Paraldehyde

1976 • 18 citations

Vigabatrin-Associated Reversible Acute Psychosis in a Child

1995 • 17 citations

Height in epilepsy.

1986 • 15 citations

Clonazepam in the Treatment of Children with Intractable Seizures

1977 • 14 citations

Unwanted Effects of Anti‐epileptic Drugs

1988 • 12 citations

American Academy of Pediatrics. Behavioral and cognitive effects of anticonvulsant therapy. Committee on Drugs.

1985 • 6 citations

Vigabatrin-induced myoclonus in four cases of partial epilepsy

1995 • 6 citations

Lamotrigine: Add-on therapy in children with refractory epilepsy

1995 • 2 citations