Regulation and control of compartmentalized glycolysis in bloodstream formTrypanosoma brucei

Enzyme structure and mechanism

1977 • 2,935 citations

Enzyme structure and mechanism

1978 • 2,897 citations

Transport and Diffusion Across Cell Membranes

1986 • 1,042 citations

Structure and mechanism

1989 • 843 citations

Metabolic control analysis: a survey of its theoretical and experimental development

1992 • 786 citations

Localization of nine glycolytic enzymes in a microbody‐like organelle in Trypanosoma brucei: The glycosome

1977 • 581 citations

Enzyme structure and mechanism (2nd edn)

1985 • 484 citations

Compartmentation of Carbohydrate Metabolism in Trypanosomes

1987 • 476 citations

Evolution of glycolysis

1993 • 448 citations

Thermodynamics and Control of Biological Free-Energy Transduction

1987 • 403 citations

Thermodynamics and control of biological free-energy transduction

1988 • 372 citations

Control of glucose utilization in working perfused rat heart.

1994 • 303 citations

Overproduction of glycolytic enzymes in yeast

1989 • 295 citations

Fermentation pathway kinetics and metabolic flux control in suspended and immobilized Saccharomyces cerevisiae

1990 • 243 citations

Glycolytic enzymes of Trypanosoma brucei. Simultaneous purification, intraglycosomal concentrations and physical properties

1986 • 216 citations

Respiration of Bloodstream Forms of the Parasite Trypanosoma brucei brucei Is Dependent on a Plant-like Alternative Oxidase

1989 • 200 citations

A Linear Steady-State Treatment of Enzymatic Chains. A Mathematical Model of Glycolysis of Human Erythrocytes

1974 • 197 citations

The regulatory principles of glycolysis in erythrocytes in vivo and in vitro. A minimal comprehensive model describing steady states, quasi-steady states and time-dependent processes

1976 • 189 citations

Control analysis of metabolic systems

1985 • 187 citations

Properties of <scp>l</scp>-α-glycerophosphate oxidase and its role in the respiration of Trypanosoma rhodesiense

1960 • 149 citations

Simultaneous purification of hexokinase, class-I fructose-bisphosphate aldolase, triosephosphate isomerase and phosphoglycerate kinase from Trypanosoma brucei

1984 • 126 citations

Glycolysis in Trypanosoma brucei

1980 • 124 citations

The mitochondrion in bloodstream forms of Trypanosoma brucei is energized by the electrogenic pumping of protons catalysed by the F₁F₀‐ATPase

1992 • 117 citations

Effects of overexpression of phosphofructokinase on glycolysis in the yeast Saccharomyces cerevisiae

1992 • 112 citations

Glucosephosphate isomerase from Trypanosoma brucei

1989 • 104 citations

Kinetics of metabolic pathways. A system in vitro to study the control of flux

1986 • 103 citations

Subcellular Compartmentation of Glycolytic Intermediates in Trypanosoma brucei

1981 • 101 citations

New approach to screening drugs for activity against African trypanosomes

1977 • 101 citations

Mitochondrial development in Trypanosoma brucei brucei transitional bloodstream forms

1991 • 100 citations

Kinetic properties of triose-phosphate isomerase from Trypanosoma brucei brucei. A comparison with the rabbit muscle and yeast enzymes

1987 • 98 citations

Regulation of glycolysis in Trypanosoma brucei: hexokinase and phosphofructokinase activity.

1982 • 93 citations

Stimulation of Trypanosoma brucei pyruvate kinase by fructose 2,6‐bisphosphate

1985 • 90 citations

Specificity and kinetics of hexose transport in Trypanosoma brucei

1989 • 83 citations

The enzymes of the classical pentose phosphate pathway display differential activities in procyclic and bloodstream forms of Trypanosoma brucei

1989 • 77 citations

The cytosolic and glycosomal glyceraldehyde‐3‐phosphate dehydrogenase from Trypanosoma brucei

1991 • 76 citations

Glucose uptake by Trypanosoma brucei. Rate-limiting steps in glycolysis and regulation of the glycolytic flux.

1991 • 69 citations

Phosphorous-31 NMR magnetization-transfer measurements of flux between inorganic phosphate and adenosine 5'-triphosphate in yeast cells genetically modified to overproduce phosphoglycerate kinase

1988 • 62 citations

Structure, function, and biogenesis of glycosomes in Kinetoplastida

1994 • 61 citations

Effects of various metabolic conditions and of the trivalent arsenical melarsen oxide on the intracellular levels of fructose 2,6‐bisphosphate and of glycolytic intermediates in Trypanosoma brucei

1987 • 61 citations

<scp>d</scp>‐Glucose Transport in Trypanosoma brucei

1978 • 60 citations

Cross-linking of the enzymes in the glycosome of Trypanosoma brucei.

1985 • 59 citations

Specificity of glucose transport in Trypanosoma brucei

1991 • 59 citations

The role of compartmentation and glycerol kinase in the synthesis of ATP within the glycosome of Trypanosoma brucei.

1985 • 59 citations

Enzyme Organization and the Direction of Metabolic Flow: Physicochemical Considerations

1992 • 58 citations

Glyceraldehyde‐phosphate dehydrogenase from Trypanosoma brucei

1987 • 55 citations

Glucose catabolism in African trypanosomes. Evidence that the terminal step is catalyzed by a pyruvate transporter capable of facilitating uptake of toxic analogs.

1993 • 55 citations

Purification and regulatory properties of phosphofructokinase from Trypanosoma (Trypanozoon) brucei brucei

1985 • 54 citations

Characterization of pyruvate kinase of Trypanosoma brucei and its role in the regulation of carbohydrate metabolism

1991 • 50 citations

Studies on glycerol kinase and its role in ATP synthesis in Trypanosoma brucei

1980 • 45 citations

Compartmentation of glycolysis in trypanosomes: a potential target for new trypanocidal drugs

1988 • 41 citations

The evolution of kinetoplastid glycosomes

1994 • 39 citations

Study of the flux and transition time control coefficient profiles in a metabolic system in vitro and the effect of an external stimulator

1989 • 37 citations

Functional reconstitution of the Trypanosoma brucei plasma‐membrane D‐glucose transporter

1993 • 31 citations

Schistosoma mansoni: Mechanisms in regulation of glycolysis

1982 • 30 citations

Improved metabolic properties of hexokinase-overloaded human erythrocytes

1988 • 29 citations

Pyruvate transport across the plasma membrane of the bloodstream form of Trypanosoma brucei is mediated by a facilitated diffusion carrier

1992 • 29 citations

The aerobic/anaerobic transition of glucose metabolism in Trypanosoma brucei

1985 • 29 citations

Kinetic studies on the reaction catalysed by phosphofructokinase from Trypanosoma brucei

1987 • 28 citations

Kinetic properties of fructose bisphosphate aldolase from Trypanosoma brucei compared to aldolase from rabbit muscle and Staphylococcus aureus

1991 • 28 citations

Some kinetic properties of pyruvate kinase from Trypanosoma brucei

1992 • 25 citations

The effect of increased phosphoglucose isomerase on glucose metabolism in Saccharomyces cerevisiae.

1994 • 21 citations

On the Physical Properties and Potential Roles of Intracellular Water

1986 • 18 citations

Control of glycolysis in rat liver by glucokinase and phosphofructokinase: influence of glucose concentration

1990 • 12 citations

Improved metabolic properties of hexokinase-overloaded human erythrocytes

1988 • 9 citations

Oligomycin‐sensitivity of hexose‐sugar catabolism in the bloodstream form of Trypanosoma brucei brucei

1994 • 8 citations

Cell metabolism: Organization in the cell soup

1985 • 6 citations