Expression of multidrug resistance in response to differentiation in the K562 human leukaemia cell line

BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTER

1993 • 3,515 citations

THE PROTEIN KINASE C FAMILY: HETEROGENEITY AND ITS IMPLICATIONS

1989 • 739 citations

Retinoids in cancer therapy.

1992 • 505 citations

Phorbol esters induce multidrug resistance in human breast cancer cells.

1988 • 241 citations

Clinical significance of P-glycoprotein in multidrug resistance malignancies [editorial] [see comments]

1993 • 231 citations

DETECTION OF A MULTIDRUG RESISTANT PHENOTYPE IN ACUTE NON-LYMPHOBLASTIC LEUKAEMIA

1987 • 223 citations

Modulation of the expression of a multidrug resistance gene (mdr-1/P-glycoprotein) by differentiating agents

1989 • 222 citations

Characterization of the human MDR3 P-glycoprotein and its recognition by P-glycoprotein-specific monoclonal antibodies.

1991 • 212 citations

Clinical significance of P-glycoprotein in multidrug resistance malignancies [editorial] [see comments]

1993 • 172 citations

The MTT cell viability assay for cytotoxicity testing in multidrug-resistant human leukemic cells

1992 • 167 citations

Expression of a drug resistance gene in human neuroblastoma cell lines: modulation by retinoic acid-induced differentiation.

1989 • 162 citations

Regulation of mdr RNA levels in response to cytotoxic drugs in rodent cells.

1990 • 155 citations

Identification of specific sites in human P-glycoprotein phosphorylated by protein kinase C.

1993 • 154 citations

Inducers of erythroid differentiation in K562 human leukemia cells.

1981 • 151 citations

Transfection with Protein Kinase Cα Confers Increased Multidrug Resistance to MCF-7 Cells Expressing P-Glycoprotein

1991 • 146 citations

Expression of the multidrug resistance gene in myeloid leukemias

1990 • 124 citations

Activation of MDR1 (P-glycoprotein) gene expression in human cells by protein kinase C agonists.

1992 • 118 citations

Differentiation of K562 leukemia cells along erythroid, macrophage, and megakaryocyte lineages.

1986 • 108 citations

Modulation of P-glycoprotein phosphorylation and drug transport by sodium butyrate

1992 • 85 citations

Atypical multidrug resistance in a therapy-induced drug-resistant human leukemia cell line (LALW-2): resistance to Vinca alkaloids independent of P-glycoprotein.

1989 • 83 citations

Transient protection of cultured human cells against antitumor agents by 12-O-tetradecanoylphorbol-13-acetate.

1987 • 64 citations

Multipotent human hematopoietic cell line K562: Lineage-specific constitutive and inducible antigens

1987 • 58 citations

Sensitivity of K562 human chronic myelogenous leukemia blast cells transfected with a human multidrug resistance cDNA to cytotoxic drugs and differentiating agents.

1993 • 40 citations

Transient enhancement of multidrug resistance by the bile acid deoxycholate in murine fibrosarcoma cells in vitro

1991 • 37 citations

Rapid functional assay for the detection of multidrug-resistant cells using the fluorescent dye rhodamine 123 [letter; comment]

1991 • 34 citations

Differentiating agents in the treatment of leukemia

1990 • 29 citations

Inhibition by erythroid differentiation factor (activin A) of P-glycoprotein expression in multidrug-resistant human K562 erythroleukemia cells.

1991 • 24 citations

In vitro effect of P-glycoprotein (P-gp) modulators on drug sensitivity of leukemic progenitors (CFU-L) in acute myelogenous leukemia (AML).

1992 • 24 citations

Cross-resistance to tumour promoters in human cancer cell lines resistant to adriamycin or cisplatin

1990 • 23 citations

Development of extended multidrug resistance in HL60 promyelocytic leukaemia cells

1994 • 22 citations

Differentiation and multidrug resistance in response to drug treatment in the K562 human leukaemia cell line

1993 • 21 citations

12-O-tetradecanoylphorbol-13-acetate and staurosporine induce increased retinoblastoma tumor suppressor gene expression with megakaryocytic differentiation of leukemic cells.

1993 • 20 citations

Effects of inducers of erythroid differentiation of human leukemia K562 cells on vincristine-resistant K562/VCR cells

1983 • 15 citations

Increase in the Level of P‐Glycoprotein mRNA Expression in Multidrug‐resistant K562 Cell Lines Treated with Sodium Butyrate Is Not Accompanied with Erythroid Differentiation

1990 • 11 citations