Human Fetal Hemoglobin Expression Is Regulated by the Developmental Stage-Specific Repressor BCL11A

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FOG, a Multitype Zinc Finger Protein, Acts as a Cofactor for Transcription Factor GATA-1 in Erythroid and Megakaryocytic Differentiation

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Genome-wide association study shows BCL11A associated with persistent fetal hemoglobin and amelioration of the phenotype of β-thalassemia

2008 • 620 citations

DNA polymorphisms at the BCL11A , HBS1L-MYB , and β- globin loci associate with fetal hemoglobin levels and pain crises in sickle cell disease

2008 • 526 citations

A QTL influencing F cell production maps to a gene encoding a zinc-finger protein on chromosome 2p15

2007 • 507 citations

Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes

2007 • 488 citations

Three functional variants of IFN regulatory factor 5 ( IRF5 ) define risk and protective haplotypes for human lupus

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Control of globin gene expression during development and erythroid differentiation

2005 • 391 citations

Bcl11a is essential for normal lymphoid development

2003 • 335 citations

The locus control region is required for association of the murine β-globin locus with engaged transcription factories during erythroid maturation

2006 • 314 citations

FOG-1 recruits the NuRD repressor complex to mediate transcriptional repression by GATA-1

2005 • 252 citations

Haemoglobin switching in human embryos: asynchrony of ζ → α and ε → γ-globin switches in primitive and definitive erythropoietic lineage

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Regulation of human fetal hemoglobin: new players, new complexities

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BCL11A is a major HbF quantitative trait locus in three different populations with β-hemoglobinopathies

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BCL11B functionally associates with the NuRD complex in T lymphocytes to repress targeted promoter

2005 • 160 citations

Rb intrinsically promotes erythropoiesis by coupling cell cycle exit with mitochondrial biogenesis

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A Conserved 12-Amino Acid Motif in Sall1 Recruits the Nucleosome Remodeling and Deacetylase Corepressor Complex

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Molecular therapies in β‐thalassaemia

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Developmental Specificity of the Interaction between the Locus Control Region and Embryonic or Fetal Globin Genes in Transgenic Mice with an HS3 Core Deletion

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Functional studies of BCL11A: characterization of the conserved BCL11A-XL splice variant and its interaction with BCL6 in nuclear paraspeckles of germinal center B cells

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Synthesis of acetylated human fetal hemoglobin.

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