Stimulation of IFN-γ, TNF-α, and TNF-β secretion in IL-2-activated T cells: Costimulatory roles for LFA-1, LFA-2, CD44, and CD45 molecules

Adhesion receptors of the immune system

1990 • 6,585 citations

Lymphokine-activated killer cell phenomenon. Lysis of natural killer-resistant fresh solid tumor cells by interleukin 2-activated autologous human peripheral blood lymphocytes.

1982 • 2,228 citations

A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1.

1986 • 1,428 citations

The major human rhinovirus receptor is ICAM-1

1989 • 1,134 citations

Heterogeneity of Cytokine Secretion Patterns and Functions of Helper T Cells

1989 • 1,122 citations

A human leukocyte differentiation antigen family with distinct alpha-subunits and a common beta-subunit: the lymphocyte function-associated antigen (LFA-1), the C3bi complement receptor (OKM1/Mac-1), and the p150,95 molecule.

1983 • 888 citations

The LFA-1 ligand ICAM-1 provides an important costimulatory signal for T cell receptor-mediated activation of resting T cells.

1990 • 799 citations

Dissection of the lymphokine-activated killer phenomenon. Relative contribution of peripheral blood natural killer cells and T lymphocytes to cytolysis.

1986 • 698 citations

Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway

1990 • 466 citations

Human monocytes and U937 cells bear two distinct Fc receptors for IgG.

1986 • 337 citations

Lymphocyte interactions with extracellular matrix

1991 • 336 citations

LFA-3, CD44, and CD45: Physiologic Triggers of Human Monocyte TNF and IL-1 Release

1990 • 300 citations

Regulation of T‐Cell Activation; Differences among T‐Cell Subsets

1989 • 271 citations

Antibodies against the CD44 p80, lymphocyte homing receptor molecule augment human peripheral blood T cell activation.

1990 • 230 citations

The accessory function of murine intercellular adhesion molecule-1 in T lymphocyte activation. Contributions of adhesion and co-activation.

1991 • 197 citations

Triggering of co-mitogenic signals in T cell proliferation by anti-LFA-1 (CD18, CD11a), LFA-3, and CD7 monoclonal antibodies.

1988 • 121 citations

Remote T cell co‐stimulation via LFA‐1/ICAM‐1 and CD2/LFA‐3: Demonstration with immobilized ligand/mAb and implication in monocyte‐mediated co‐stimulation

1991 • 94 citations

Noncovalently bonded subunits of 22 and 28 kd are rapidly internalized by T cells reacted with anti-Leu-4 antibody.

1983 • 86 citations

Tumor targets stimulate IL-2 activated killer cells to produce interferon-gamma and tumor necrosis factor.

1989 • 79 citations

Complementary roles for CD2 and LFA‐1 adhesion pathways during T cell activation

1991 • 72 citations

The role of cell surface recognition structures in the initiation of MHC-unrestricted ‘promiscuous’ killing by T cells

1989 • 57 citations

Purified lymphocyte function-associated antigen-3 (LFA-3) activates human thymocytes via the CD2 pathway.

1988 • 50 citations

Signaling via the inositol phospholipid pathway by T cell antigen receptor is limited by receptor number.

1991 • 37 citations

CD45R gives immunofluorescence and transduces signals on mouse T cells

1988 • 30 citations

Phenotypic analyses of lymphokine-activated killer cells that release interferon γ and tumor necrosis factor α

1990 • 8 citations